UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

SCHEDULE 14A

(Rule14a-101)

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

 

Filed by the Registrant                              Filed by a Party other than the Registrant  

Check the appropriate box:

 

Preliminary Proxy Statement

Preliminary Proxy Statement

Confidential, For Use of the Commission Only (as permitted by Rule14a-6(e)(2))

Definitive Proxy Statement

Definitive Additional Materials

Soliciting Material Pursuant to §240.14a-12

ENANTA PHARMACEUTICALS, INC.

(Name of Registrant as Specified in Its Charter)

 

(Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

Payment of filing fee (Check the appropriate box):

No fee required

Fee computed on table below per Exchange Act Rules14a-(6) (i) (1) and0-11.

(1)

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(2)

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(3)

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(4)

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(5)

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Fee paid previously with preliminary materials.

Check box if any part of the fee is offset as provided by Exchange Act Rule0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the form or schedule and the date of its filing.

(1)

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(2)

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(3)

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ENANTA PHARMACEUTICALS, INC.

500 Arsenal Street

Watertown, Massachusetts 02472

(617)607-0800

NOTICE OF ANNUAL MEETING OF STOCKHOLDERS TO BE HELD FEBRUARY 28, 2019MARCH 2, 2021

The 20192021 Annual Meeting of Stockholders (the “2021 Annual Meeting”) of Enanta Pharmaceuticals, Inc. (“Enanta”), a Delaware corporation, will be held at The Charles Hotel, 1 Bennett Street, Cambridge, Massachusetts 02138,virtually at 4:3000 p.m. local time on Thursday, February 28, 2019,Tuesday, March 2, 2021 via live audio webcast at www.proxydocs.com/ENTA for the following purposes:

 

1.

To elect two Class IIIII directors to serve until the 20222024 Annual Meeting of Stockholders.

 

2.

To approve thean amendment to Enanta’s 2019 Equity Incentive Plan which will replaceto increase the 2012 Equity Incentive Plan.number of shares of Common Stock reserved for issuance under the plan by 950,000 shares.

 

3.

To approve, on an advisory basis, the frequency of holding an advisory vote on the compensation paid to our named executive officers.3.

4.

To approve, on an advisory basis, the compensation paid to our named executive officers, as disclosed in thisthe accompanying proxy statement.

 

5.

4.

To ratify the appointment of PricewaterhouseCoopers LLP as Enanta’s independent registered public accounting firm for the 20192021 fiscal year.

 

6.

5.

To transact any other business that may properly come before the meeting or any adjournment thereof.

The record date for the 20192021 Annual Meeting is January 4, 2019.8, 2021. Accordingly, only stockholders of record at the close of business on that date may vote at the meeting or any adjournment thereof.

It is importantYou may vote on these matters in person (virtually), by proxy or via the internet or telephone. In light of the coronavirus (COVID-19) pandemic, to provide our stockholders with a means to attend the annual meeting in a manner that does not endanger the health and well-being of our stockholders and our employees, we have elected to hold our annual meeting via remote communication. You may attend the virtual annual meeting and vote your shares be representedduring the meeting by visiting our annual meeting website at the meeting. Therefore, whetherwww.proxydocs.com/ENTA.

Whether or not you plan to attend the virtual meeting, pleasewe ask that you promptly complete and return your proxy card by mail or vote via the internet or telephone, so that your shares will be represented and return itvoted at the meeting in accordance with your wishes.

You are entitled to participate in and submit questions in writing during the annual meeting if you were a stockholder as of the close of business on January 8, 2021. To participate in the enclosed envelope, which requires no postage if mailed2021 Annual Meeting virtually via the Internet, please visit www.proxydocs.com/ENTA. In order to attend, you must register in advance at www.proxydocs.com/ENTA prior to the United States. Ifdeadline of February 26, 2021 at 5:00 pm Eastern Time. Upon completing your registration, you attendwill receive further instructions via email, including your unique links that will allow you access to the meeting and wishwill permit you to vote in person, your proxysubmit questions. You will not be used.

By orderable to attend the 2021 Annual Meeting in person. For instructions on how to vote your shares, please refer to the instructions on the Notice of Internet Availability of Proxy Materials you received in the mail, the section titled “How do I Vote” in the Proxy Statement or, if you requested to receive printed proxy materials, your enclosed proxy card. A list of our registered holders as of the Boardclose of Directors,business on the record date will be made available to stockholders during the meeting at www.proxydocs.com/ENTA.

By order of the Board of Directors,

January 21, 2021

Nathaniel S. Gardiner

Secretary

Nathaniel S. Gardiner

Secretary

January 18, 2019

IMPORTANT NOTICE REGARDING THE AVAILABILITY OF PROXY MATERIALS FOR THE

ANNUAL MEETING OF STOCKHOLDERS TO BE HELD ON FEBRUARY 28, 2019MARCH 2, 2021

This proxy statement and our Annual Report are available online at the “Investors – 2021 Annual Meeting Materials” section of our website atwww.enanta.com. To obtain directionsFor more information about how to The Charles Hotel in order to attend the annualaccess our virtual meeting, in person, please visit the “Investors – 2021 Annual Meeting Materials” section of our website atwww.enanta.comor contact Investor Relations at (617)607-0710.



 


PROXY STATEMENT

 

INFORMATION CONCERNING SOLICITATION AND VOTING

We are soliciting proxies from our stockholders to vote at our 20192021 Annual Meeting of Stockholders, or at any continuation, postponement or adjournment thereof, for the purposes discussed in this proxy statement. The annual meeting will be held virtually at 4:3000, p.m. local time on Thursday, February 28, 2019Tuesday, March 2, 2021 at The Charles Hotel, 1 Bennett Street, Cambridge, Massachusetts 02138. www.proxydocs.com/ENTA. For directionsmore information on how to The Charles Hotel in order to attendaccess the annualvirtual meeting, in person, please visit the “Investors – 20192021 Annual Meeting Materials” section of our website atwww.enanta.comor contact Investor Relations at (617)607-0710.

The proxy materials, including this proxy statement and our 20182020 annual report to stockholders, are being distributed and made available on the Internetinternet at the “Investors – 20192021 Annual Meeting Materials” section of our website atwww.enanta.comon or about January 18, 2019.21, 2021.

This proxy statement contains important information for you to consider when deciding how to vote on the matters brought before the meeting. Please read it carefully.

All references in this proxy statement to a particular year, e.g. 2018,2020, refer to our twelve-month fiscal year ended on September 30 of that year, e.g. September 30, 2018,2020, unless the context indicates otherwise.

QUESTIONS AND ANSWERS ABOUT THE ANNUAL MEETING AND VOTING

Why did I receive these materials?

We are soliciting proxies for our annual meeting of stockholders to be held on Thursday, February 28, 2019.Tuesday, March 2, 2021. You are receiving a proxy statement because you owned shares of our common stock on January 4, 2019,8, 2021, the record date for the specialannual meeting, and that ownership entitles you to vote at the meeting. By use of a proxy, you can vote, whether or not you attend the meeting.meeting at www.proxydocs.com/ENTA.

When and where is the Annual Meeting?

The annual meeting will be held at The Charles Hotel located at 1 Bennett Street, Cambridge, Massachusetts 02138virtually at 4:3000 p.m. on Thursday, February 28, 2019,Tuesday, March 2, 2021, or at any future date and time following an adjournment or postponement of the meeting.meeting, at www.proxydocs.com/ENTA. In order to attend, you must register in advance at www.proxydocs.com/ENTA prior to the deadline of February 26, 2021 at 5:00 pm Eastern Time. Upon completing your registration, you will receive further instructions via email, including your unique links that will allow you access to the meeting and will permit you to submit questions.

What proposals will be voted on at the Annual Meeting?

The fivefour proposals to be considered and voted on at the annual meeting, as set forth in the accompanying Notice of Annual Meeting of Stockholders, are:

 

(i)

the election of two Class IIIII directors;

 

(ii)

(ii)

an amendment to increase the approvalnumber of  shares reserved for issuance under the 2019 Equity Incentive Plan;

 

(iii)

an advisory vote on the frequency of advisory votes on executive compensation;(iii)

(iv)

an advisory vote on executive compensation; and

 

(v)

(iv)

the ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the 20192021 fiscal year.

As far as we know, the only matters to be brought before the annual meeting are those referred to in this proxy statement. If any additional matters are presented at the annual meeting, the persons named as your proxies may vote your shares in their discretion.

Do

How do I have to attendvote?

Beneficial Owner: Shares Registered in the meeting to vote?Name of a Broker or Bank.

No.If on January 8, 2021 your shares were held in an account at a brokerage firm, bank, dealer, or other similar organization, then your shares are held in “street name” and you are the beneficial owner and not the record owner of the shares. If you wantare a beneficial owner of shares registered in the name of your broker, bank, or other agent, you

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should have received a notice and proxy card with voting instructions from that organization rather than from us. If you are a beneficial owner, you can vote in the following ways:

By Mail: To vote using the proxy card supplied by your broker or bank, please complete and mail that proxy card to haveensure that your vote count atis counted.

By Internet/Telephone: To vote over the meeting, but not actually attendinternet, or by telephone, please follow any instructions provided by your broker or bank if either alternative is made available to you.  

At Virtual Meeting: If you have followed the meetingprocedures described in person,this proxy statement for obtaining credentials for the meeting, you may vote by granting a proxy or,online while attending the meeting virtually at www.proxydocs.com/ENTA and following the instructions for shares heldstockholder voting. In order to attend, you must register in street name, by submitting votingadvance at www.proxydocs.com/ENTA prior to the deadline of February 26, 2021 at 5:00 pm Eastern Time. Upon completing your registration, you will receive further instructions via email, including your unique links that will allow you access to your broker or nominee. The following summary outlines the various procedures for voting:meeting and will permit you to submit questions.

Stockholder of Record: Shares Registered in Your Name.

If on January 4, 20198, 2021 your shares were registered directly in your name with our transfer agent, then you are a stockholder “of record.” If you are a stockholder of record, you may vote in person at the annual meeting or by mail. Whether or not you plan to attend the meeting, we urge you to vote by proxy to ensure your vote is counted. You may still attend the meeting and vote in person if you have already voted by proxy. Voting in person will revoke your proxy. There are threefour ways for you to vote:

To vote in person, please come to the annual meeting and we will give you a ballot when you arrive.

By Mail:To vote using the proxy card, please complete, sign and date the proxy card furnished to you with the notice of this meeting and return it promptly in the envelope provided. If you return your signed proxy card to us before the annual meeting, we will vote your shares as you direct.

By Internet: To vote via the internet, access the website for our meeting at: www.proxypush.com/enta using the voter control number printed on the proxy card furnished to you with the notice of this meeting. Your shares will be voted in accordance with your instructions. You must specify how you want your shares voted or your internet vote cannot be completed and you will receive an error message. If you vote on the internet, you may also request electronic delivery of future proxy materials.

To vote via the internet, access the website for our meeting at:www.proxypush.com/enta using the voter control number printed on the proxy card furnished to you with the notice of this meeting. Your shares will be voted in accordance with your instructions. You must specify how you want your shares voted or your Internet vote cannot be completed and you will receive an error message. If you vote on the Internet, you may also request electronic delivery of future proxy materials.

Beneficial Owner: Shares RegisteredBy Telephone: If you live in the Name of a BrokerUnited States or Bank.

If on January 4, 2019 your shares were held not in your name, but rather in an account at a brokerage firm, bank, dealer, or other similar organization, then your shares are held in “street name” and you are the beneficial owner and not the record owner of the shares. If you are a beneficial owner of shares registered in the name of your broker, bank, or other agent, you should have received a proxy card and voting instructions with these proxy materials from that organization rather than from us. Please complete and mail that proxy card to ensure that your vote is counted. Alternatively,Canada, you may vote overby proxy by calling toll-free 1-866-892-1702 and by following the Internet, if instructed by your broker or bank that you may do so. To vote in person atinstructions provided on the annual meeting,proxy card. When voting, you must obtain a validhave the voter control number printed on the proxy from your broker, bank or other agent. Followcard furnished to you with the notice of this meeting.

At Virtual Meeting: You may vote online while attending the meeting virtually at www.proxydocs.com/ENTA and following the instructions fromfor stockholder voting. In order to attend, you must register in advance at www.proxydocs.com/ENTA prior to the deadline of February 26, 2021 at 5:00 pm Eastern Time. Upon completing your broker or bank included with these proxy materials or contactregistration, you will receive further instructions via email, including your broker or bankunique links that will allow you access to request such a proxy form.the meeting and will permit you to submit questions.

Who can vote at the Annual Meeting?

Only stockholders of record at the close of business on January 4, 2019,8, 2021, the record date, are entitled to notice of, and to vote at, the annual meeting or any adjournment or postponement of the meeting. On the record date, we had outstanding 19,435,12820,142,806 shares of common stock, each of which is entitled to one vote upon each of the matters to be presented at the meeting.

You may contact our Secretary and General Counsel, Nathaniel S. Gardiner, at (617) 607-0800 to make arrangements to review a copy of the stockholder list at our offices in Watertown, MA, between the hours of 9:00 a.m. and 5:00 p.m., Eastern time, on any business day from February 19, 2021 to the time of the annual meeting. Please understand that we are complying with COVID-19 rules promulgated by the Commonwealth of Massachusetts. You will need to comply with our COVID-19 protocols for these rules, including confirming that you do not have symptoms of COVID-19 or any recent exposure to it and wearing a mask and adhering to social distancing requirements. It will also be necessary to plan a meeting time and place to provide access to our facility where the stockholder list is maintained.

See “DoHow do I have to attend the meeting to vote” above for more information regarding voting.

2


What is the quorum requirement?

A quorum of stockholders is necessary to hold a valid meeting. A quorum will be present if at least a majority of the outstanding shares are represented by stockholders present at the meeting or present by proxy. On

the record date, there were 19,435,12820,142,806 shares outstanding and entitled to vote. Thus, 9,717,56510,071,404 shares must be represented by stockholders present at the meeting in person or by proxy to have a quorum.

Your shares will be counted towards the quorum only if you submit a valid proxy (or one is submitted on your behalf by your broker, bank or other nominee) or if you vote in person at the meeting. Abstentions and brokernon-votes will be counted towards the quorum requirement. If there is no quorum, a majority of the votesshares present at the meeting may vote to adjourn the meeting to another date.

How are votes counted?

Votes will be counted by the inspector of election appointed for the meeting, who will separately count “For” and “Withhold” and, with respect to proposals other than the election of directors, “Against” votes, abstentions and brokernon-votes. Abstentions and brokernon-votes have no effect and will not be counted towards the vote total for any proposal.

If your shares are held by your broker in “street name”, you will need to obtain a proxy form from the institution that holds your shares and follow the instructions included on that form regarding how to instruct your broker to vote your shares. If you do not give instructions to your broker, your broker can vote your shares with respect to “discretionary” items, but not with respect to“non-discretionary” “non-discretionary” items. Discretionary items are proposals considered routine on which your broker may vote shares held in street name in the absence of your voting instructions.Non-discretionary items are matters such as mergers, stockholder proposals, executive compensation and elections of directors. Onnon-discretionary items for which you do not give your broker instructions, the shares will be treated as broker non-votes. non-votes.If your shares are held by a broker, bank or other nominee and you wish to vote online while virtually attending the meeting, you will need to access the live audio webcast of the meeting at www.proxydocs.com/ENTA and follow the instructions for stockholder voting. In order to attend, you must register in advance at www.proxydocs.com/ENTA prior to the deadline of February 26, 2021 at 5:00 pm Eastern Time. Upon completing your registration, you will receive further instructions via email, including your unique links that will allow you access to the meeting and will permit you to submit questions.

What if I return a proxy card but do not make specific choices?

If you return a signed and dated proxy card without marking any voting selections, your shares will be voted

“For” our two nominees for director;

“For” approvalthe amendment to increase the number of shares reserved for issuance under the 2019 Equity Incentive Plan;

“For” the frequency of an advisory vote on executive compensation every year;

“For” the approval, on an advisory basis, of the compensation paid to our named executive officers; and

“For” ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for our 20192021 fiscal year.

Can I change my vote after submitting my proxy?

Yes. You can revoke your proxy at any time before the final vote at the meeting. IfYes, if you are thea record holder of your shares, you maycan revoke your proxy in any one of four ways:

You may submit another properly completed proxy vote with a later date which must be delivered in person atyour revocation by telephone prior to the meeting or by mail or any other method specified byclose of the record holder if your shares are held in street name.telephone voting facility.

You may submit your revocation over the Internet or by telephoneinternet prior to the close of the Internet voting facility or the telephoneinternet voting facility.

You may send a written notice that you are revoking your proxy to our Secretary, Nathaniel S. Gardiner, c/o Enanta Pharmaceuticals, Inc., 500 Arsenal Street, Watertown, Massachusetts 02472.

You may attend the annual meeting virtually and vote in person. Simply attendingonline during the meeting will not, by itself, revoke your proxy.meeting.

If you are a beneficial owner and your shares are held by your broker or bank as a nominee or agent, you should follow the instructions provided by your broker or bank.bank for revoking your proxy.

What is the vote required for a proposal to pass?

Proposal 1. Directors are elected by a plurality of the votes cast by the holders of a plurality of the shares represented in person or by proxy is required for the election of directors. Broker non-votes and proxies marked to withhold authority with respect to the election of one or more Class II directors will not be voted with respect to the director indicated. The two director nominees receiving the highest number of votes will be elected.

3


Proposal 2. The affirmative vote of the holders of a majority of the votes cast at the meeting is required for approval of the proposed amendment to increase the number of shares reserved for issuance under the 2019 Equity Incentive Plan. Abstentions and broker non-votes will have no effect on the voting outcome.

Proposal 3. The affirmative vote of the holders of a majority of the votes cast at the meeting is required for approval of the advisory resolution to approve the compensation of our named executive officers. Abstentions and broker non-votes will have no effect on the voting outcome.

Proposal 4. The affirmative vote of the holders of a majority of the votes cast at the meeting is required for approval of the vote to ratify the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the 2021 fiscal year. Abstentions and broker non-votes will have no effect on the voting outcome.

Proposal 1. The affirmative vote of the holders of a plurality of the shares represented in person or by proxy is required for the election of directors. Brokernon-votes and proxies marked to withhold authority with respect to the election of one or more Class III directors will not be voted with respect to the director indicated. The two director nominees receiving the highest number of votes will be elected.

Proposal 2. The affirmative vote of the holders of a majority of the votes cast at the meeting is required for approval of the resolution to approve the 2019 Equity Incentive Plan. Abstentions and brokernon-votes will have no effect on the voting outcome.

Proposal 3. Because stockholders have several voting choices with respect to the advisory resolution on the frequency of future advisory votes on executive compensation, it is possible that no single choice will receive a majority vote. The board of directors will consider the outcome of the vote when determining the frequency of future advisory votes on executive compensation. While the board is making a recommendation with respect to Proposal 3, stockholders are being asked to vote on the choices specified on the proxy card, and not whether they agree or disagree with the board’s recommendation. Abstentions and brokernon-votes will have no effect on the voting outcome.

Proposal 4. The affirmative vote of the holders of a majority of the votes cast at the meeting is required for approval of the advisory resolution to approve the compensation of our named executive officers. Abstentions and brokernon-votes will have no effect on the voting outcome.

Proposal 5. The affirmative vote of the holders of a majority of the votes cast at the meeting is required for approval of the vote to ratify the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the 2019 fiscal year. Proxies marked as abstentions on such matter will not be voted, although they will be counted for purposes of determining whether there is a quorum at the meeting. Abstentions and brokernon-votes will have no effect on the voting outcome.

How can I find out the results of the voting at the Annual Meeting?

Preliminary voting results will be announced at the annual meeting. Final voting results will be published in a Current Report on Form8-K, or Form8-K, that we expect to file with the Securities and Exchange Commission, or SEC, within four business days after the annual meeting. If final voting results are not available to us in time to file a Form8-K within four business days after the annual meeting, we intend to file a Form8-K to publish preliminary results and, within four business days after the final results are known to us, file an additional Form8-K to publish the final results.

Who is paying for this proxy solicitation?

We will pay for the entire cost of soliciting proxies. In addition to mailing the proxy materials, our officers, directors and employees may also solicit proxies in person, by telephone, or by other means of communication. Officers, directors and employees will not be paid any additional compensation for soliciting proxies. We maywill also utilizerequest brokerage houses, custodians, nominees, and fiduciaries to forward copies of the assistance of third parties in connection with our proxy solicitation effortsmaterial to those persons for whom they hold shares, and we would compensate such third partieswill reimburse those record holders for their efforts.reasonable expenses in transmitting this material. In addition, we have engaged The Proxy Advisory Group, LLC to assist in the solicitation of proxies and provide related advice for a services fee and reimbursement of customary disbursements, which are not expected to exceed $18,000, in total.

Householding of Annual Meeting Materials

Some banks, brokers and other nominee record holders may be “householding” our proxy statements and annual reports. This means that only one copy of our proxy statement and annual report to stockholders may have been sent to multiple stockholders in your household. We will promptly deliver a separate copy of either

document to you if you call or write us at our principal executive offices, 500 Arsenal Street, Watertown, Massachusetts 02472, Attn: Investor Relations, telephone: (617)607-0710. In the future, if you want to receive separate copies of the proxy statement or annual report to stockholders, or if you are receiving multiple copies and would like to receive only one copy per household, you should contact your bank, broker, or other nominee record holder, or you may contact us at the above address and telephone number.

No Appraisal Rights

There are no appraisal rights associated with any of the proposals being considered at the annual meeting.

BENEFICIAL OWNERSHIP OF COMMON STOCK

The following table and footnotes set forth certain information regarding the beneficial ownership of our common stock as of December 1, 201815, 2020 by (i) persons known by us to be beneficial owners of more than 5% of our common stock, (ii) each of our current executive officers named in the Summary Compensation Table included in “Executive Compensation” below, (iii) our current directors and (iv) all our current executive officers and directors as a group. The percentage of shares beneficially owned is computed on the basis of 19,427,63620,141,923 shares of our common stock outstanding as of December 1, 2018.15, 2020.

Beneficial ownership is determined in accordance with the rules and regulations of the SEC and includes voting or investment power with respect to our common stock. Shares of our common stock that a person has the right to acquire within 60 days of December 1, 201815, 2020 are deemed outstanding for purposes of computing the percentage ownership of the person holding such rights but are not deemed outstanding for purposes of computing the percentage ownership of any other person, except with respect to the percentage ownership of all directors and executive officers as a group. Except as otherwise indicated in the footnotes below, we believe the persons and entities in this table have sole voting and investing power with respect to all of the shares of our common stock beneficially owned by them, subject to

4


community property laws, where applicable. Except as otherwise indicated in the footnotes below, the address of the beneficial owner is c/o Enanta Pharmaceuticals, Inc., 500 Arsenal Street, Watertown, MA 02472.

 

  Beneficially Owned Number
of Shares
 

 

Beneficially Owned Number of Shares

 

Beneficial Owner

  Shares     Percent 

 

Shares

 

 

Percent

 

BlackRock Inc.(1)

   2,397,739    12.34

 

 

3,215,507

 

 

 

15.96

%

Shionogi & Co., Ltd(2)

   1,599,760    8.23

Farallon Capital Management, LLC (2)

 

 

1,775,000

 

 

 

8.81

%

The Vanguard Group, Inc.(3)

   1,426,791    7.34

 

 

1,720,890

 

 

 

8.54

%

State Street Corp(4)

   1,199,167    6.17

Alan J. Dworsky and affiliates(5)

   1,175,233    6.05

T. Rowe Price Associates(6)

   1,063,084    5.47

Alan J. Dworsky and affiliates(4)

 

 

1,209,773

 

 

 

6.01

%

Renaissance Technologies LLC (5)

 

 

1,029,000

 

 

 

5.11

%

Jay R. Luly, Ph.D.

   1,024,301   (7)  5.16

 

 

1,269,713

 

(6)

 

6.12

%

Yat Sun Or, Ph.D.

   495,640   (8)  2.53

 

 

524,368

 

(7)

 

2.58

%

Nathalie Adda, M.D.

 

 

177,739

 

(8)

*

 

Paul J. Mellett

   262,704   (9)  1.35

 

 

159,724

 

(9)

*

 

Nathalie Adda, M.D.

   96,395   (10)  * 

Nathaniel S. Gardiner, J.D.

   155,027   (11)  * 

Stephen Buckley, Jr.

   39,436    (12 )   * 

Nathaniel S. Gardiner, J.D

 

 

215,879

 

(10)

 

1.06

%

Bruce L. A. Carter, Ph.D.

   28,155    (13 )   * 

 

 

41,166

 

(11)

*

 

George S. Golumbeski, Ph.D.

   28,155    (14 )   * 

Mark G. Foletta

 

 

3,305

 

(12)

*

 

George Golumbeski, Ph.D.

 

 

27,666

 

(13)

*

 

Kristine Peterson

   1,389    (15 )   * 

 

 

30,416

 

(14)

*

 

Lesley Russell, MBChB, MRCP

   4,859    (16 )   * 

 

 

34,166

 

(15)

*

 

Terry C. Vance

   44,610    (17 )   * 

Terry Vance

 

 

66,901

 

(16)

*

 

All current directors and executive officers as a group (12 persons)

   2,356,506   (18)  11.35

 

 

2,534,398

 

(17)

 

11.74

%

*Less than 1%

*

Less than 1%

Excludes all shares that may be issuable after December 1, 201815, 2020 under outstanding performance share units or relative total stockholder return units issued to management, as none of such shares were issuable within 60 days after December 1, 2018.15, 2020.

(1)

BlackRock Inc. reports that it holds, directly or through one or more of its subsidiaries, sole investment power with respect to all these shares, and sole voting power with respect to 2,341,8273,123,255 of these shares and no voting power with respect to the remainder. This information is as of September 30, 2018,2020, based solely on a Schedule13F-HR filed by BlackRock Inc. on November 9, 2018.6, 2020. The address listed for BlackRock Inc. is 55 East 52nd Street, New York, New YorkNY 10055.

(2)

VotingFarallon Capital Management, LLC reports that it holds sole voting and investmentdispositive power over the shares held by Shionogi & Co., Ltd. is exercised by its Representative Directors (i.e., Motozo Shiono and Isao Teshirogi) or Vice Presidentall of Finance & Accounting Department (i.e., Yuji Hosogai).these shares. This information is based solely on a Schedule 13G13F-HR filed by Shionogi & Co., Ltd.Farallon Capital Management, LLC on January 29, 2014.November 16, 2020. The address listed for Shionogi & Co., Ltd. and for the individuals listed aboveFarallon Capital Management, LLC is c/o Shionogi & Co., Ltd.1-8, Doshomachi3-chome,Chuo-ku, Osaka541-0045, Japan.One Maritime Plaza, Suite 2100, San Francisco, CA 94111.

(3)

Vanguard Group, Inc. reports that it holds, directly or through one or more of its subsidiaries, (i) sole investment power and no voting power with respect to 1,391,0721,688,577 of these shares, (ii) sole investment and voting power with respect to 1,439125 of these shares, (iii)  shared investment power and sole voting power with respect 1,204to 19,499 of these shares and (iv) shared investment power and no voting power with respect to 33,07612,689 of these shares. This information is based solely on a Schedule13F-HR/A 13F-HR filed by Vanguard Group, Inc. on December 13, 2018.November 16, 2020. The address listed for Vanguard Group, Inc. is P.O. Box 2600, V26, Valley Forge, PA 19482-2600.

(4)

State Street Corp. reports that it holds, directly or through one or more or one of its subsidiaries, sole investment power with respect to all these shares, and sole voting power with respect to 1,136,183 of these shares and no voting power with respect to the remainder. This information is based solely on a Schedule13F-HR filed by State Street Corp. on November 9, 2018. The address listed for State Street Corp. is 1 Lincoln Street, Boston, MA 02111.

(5)

Mr. Dworsky reports that he hasbeneficially owns an aggregate of 1,209,773 shares of Common Stock comprised of (i) shared voting and dispositive power over 809,117325,386 shares held by the Alan J. Dworsky 1988 Trust u/d/t dated January 6, 1988, as amended, of which Mr. Dworsky is a trustee and over which shares Mr. Dworsky has shared voting and dispositive power, (ii) 516,298 shares held by the Dworsky Family 2017 Retained Annuity Trust, of which Mr. Dworsky is a trustee and over which shares Mr. Dworsky has sole voting and dispositive power, over 227,198(iii) 219,100 shares held by the Alan J. Dworsky Grandchildren’s Trusts u/d/t dated July 14, 1995, as amended, of which Mr. Dworsky is a trustee and (iii)over which shares Mr. Dworsky has sole voting and dispositive power, over 138,918and (iv) 148,989 shares held by the Popplestone Foundation u/d/t dated August 15, 2000, of which Mr. Dworsky is a trustee.trustee and has shared voting and dispositive power. This information is based solely on a Schedule 13G/A filed by Mr. Dworsky with the SEC on January 22, 2018.23, 2020. The address listed for Mr. Dworsky is 8 Mercer Circle, Cambridge, MA 02138.

(6)

(5)

T. Rowe Price Associates Inc.Renaissance Technologies, LLC reports that it holds sole investmentvoting and dispositive power with respect toover all these shares, and sole voting power with respect to 132,097 of these shares and no voting power with respect to the remainder.shares. This information is based solely on a Schedule 13F-HR filed by T. Rowe Price Associates Inc.Renaissance Technologies, LLC on November 14, 2018.13, 2020. The address listed for T. Rowe Price Associates Inc.Renaissance Technologies, LLC is 100 East Pratt Street, Baltimore, MD 21289.800 Third Avenue, New York, NY 10022.

5


(7)

(6)

Consists of (i) 601,524654,988 shares of common stock and (ii) 422,777614,725 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(8)

(7)

Consists of (i) 309,920309,625 shares of common stock and (ii) 185,720214,743 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(9)

(8)

Consists of (i) 80,41819,344 shares of common stock and (ii) 182,286158,395 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020. 

(10)

(9)

Consists of 96,395(i) 48,159 shares of common stock and (ii) 111,565 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020. Pursuant to a qualifying domestic relations order issued on November 19, 2019, one half of all Enanta securities held by Mr. Mellett on September 30, 2019 were transferred to his former spouse.

(11)

(10)

Consists of (i) 13,82734,648 shares of common stock held directly by Mr. Gardiner, (ii) 16,645 shares of common stock held by a grantor retained annuity trusts of which Mr. Gardiner is a trustee and (ii) 141,200the primary beneficiary, and (iii) 164,586 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(12)

(11)

Consists of (i) 2,000 shares of common stock and (ii) 44,31141,166 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(13)

(12)

Consists of 35,0303,305 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(14)

(13)

Consists of 35,03027,666 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(15)

(14)

Consists of 8,68030,416 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(16)

(15)

Consists of 15,27634,166 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(17)

(16)

Consists of (i) 15,295 shares of common stock and (ii) 36,19051,606 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

(18)

(17)

See Notes 76 through 17.16. Consists of (i) 1,029,1111,082,059 shares of common stock and (ii) 1,327,3951,452,339 shares of common stock issuable upon exercise of outstanding options that were exercisable within the60-day period following December 1, 2018.15, 2020.

Delinquent Section 16(a) Beneficial Ownership Reporting ComplianceReports

Our executive officers and directors and persons who own beneficially more than 10% of our equity securities are required under Section 16(a) of the Securities Exchange Act of 1934 to file reports of ownership and changes in their ownership of our securities with the SEC. They must also furnish copies of these reports to us. Based solely on a review of the copies of reports furnished to us and written representations that no other reports were required, we believe that for our 20182020 fiscal year our executive officers, directors and 10% beneficial owners complied with all applicable Section 16(a) filing requirements except that Drs. Carter, GolumbeskiLuly, Adda and Russell,Or, and Messrs. BuckleyMellett and Vance and Ms. PetersonGardiner each filed one late Form 4 on March 5, 2018January 6, 2020 with respect to a grant of optionsrestricted stock units that settled and issued on February 28, 2018.

December 18, 2019.

6


PROPOSALPROPOSAL 1

ELECTION OF DIRECTORS

Our Board of Directors has fixed the number of directors at seven.six. Under our charter, our Board is divided into three classes, with each class having as nearly as possible an equal number of directors. The term of one class expires, with their successors being subsequently elected to a three-year term, at each annual meeting of stockholders. At the 2019 annual meeting,2021 Annual Meeting, the two nominees named in this proxy statement as Class IIIII Directors will be elected to hold office for three years until their successors are elected and qualified. The Board has nominated Lesley Russell, MBChB, MRCPKristine Peterson and Stephen Buckley, Jr.Terry C. Vance forre-election as Class IIIII Directors at the upcoming annual meeting. Dr. RussellAs previously reported, George Golumbeski decided not to stand for re-election after he completes his second term as an independent director at the 2021 Annual Meeting. Ms. Peterson and Mr. BuckleyVance are independent directors as defined by applicable Nasdaq Stock Market standards governing the independence of directors. Each nominee has consented to serve, if elected. If any nominee is unable to serve, proxies will be voted for any replacement candidate nominated by our Board of Directors.

Votes Required

Directors will be elected by a plurality of the votes cast by the stockholders entitled to vote on this proposal at the meeting. Brokernon-votes and proxies marked to withhold authority with respect to one or more Class IIIII directors will not be treated as votes cast for this purpose and, therefore, will not affect the outcome of the election.

Nominees for Director and Current Directors

The following table contains biographical information as of December 1, 201815, 2020 about the nominees for Class IIIII Directors and current directors whose terms of office will continue after the annual meeting. The table includes information provided by the directors individually as to their age, current position, principal occupation and experience for the past five years, and the names of other publicly-held companies for which they currently serve as a director or have served as a director during the past five years.

Current SEC rules require us to discuss briefly the specific experience, qualifications, attributes or skills that led the Board to conclude that each director or nominee for director should serve on our Board of Directors. We have provided this discussion in a separate paragraph immediately below the biographical information provided for each director.

As you read the disclosure, please keep in mind that any specific qualification, attribute or skill that is attributed to one director should not necessarily imply that other directors do not possess that qualification, attribute or skill. Furthermore, this disclosure does not impose on any director any duties, obligations or liability that are greater than the duties, obligations, and liability imposed on each other member of the Board.

Because the discussion of the specific experience, qualifications, attributes or skills of a director is to be made each year in light of Enanta’s business and structure at that time, the content of this discussion may change for one or more directors in future years.

7


Name and Age

Business Experience During Past Five Years

and Other Directorships


Director

Since


Class III Directors (present term expires in 2019)

Lesley Russell, MBChB, MRCP

Age: 58

Lesley Russell, MBChB, MRCP, was elected to our board of directors in November 2016. Dr. Russell served as Chief Medical Officer of Innocoll Holdings Plc., a public biotechnology company, from April 2016 until November 2017. Dr. Russell previously served as Chief Operating Officer and Chief Medical Officer of TetraLogic Pharmaceuticals, another public biotechnology company, from August 2013, and prior to that during 2013 she operated as an independent consultant. Dr. Russell was a medical executive with Cephalon, Inc. from January 2000 to 2011, most recently as Executive Vice President and Chief Medical Officer from September 2006 until October 2011, when Cephalon was acquired by Teva Pharmaceuticals. Dr. Russell served as a Senior Vice President and Global Head, Research and Development for Global Branded Products from the acquisition until July 2012. Dr. Russell previously held positions in medical research at US Bioscience, Eli Lilly and Amgen. Dr. Russell serves as an independent director of AMAG Pharmaceuticals, Inc., a public specialty pharmaceutical company, and Endocyte Pharmaceuticals, Inc., a public biotechnology company. Dr. Russell holds a Bachelor of Medicine, Bachelor of Surgery (MBChB) from the University of Edinburgh and is a member of the Royal College of Physicians (MRCP), UK.

We believe that Dr. Russell is qualified to serve on our board of directors due to her business and drug development experience, her service on other public company boards and her knowledge of our industry.

2016

Stephen Buckley, Jr.

Age: 69

Stephen Buckley, Jr., was elected to our board of directors in September 2012. Mr. Buckley was for 25 years a partner of Ernst & Young, where he led assurance and advisory teams serving public and private companies in life sciences and other technologies. Mr. Buckley led Ernst & Young’s Life Sciences Industry Practice of New England from 1991 to 2006, and was Director of its New England Entrepreneurial Services Group from 1991 to 2001. He was previously a partner in the Boston, Massachusetts office of Arthur Young until its merger into Ernst & Young in 1989. Mr. Buckley is a member of the American Institute of CPAs. Mr. Buckley received an A.B. from Bowdoin College and a Master of Science in Accounting from Northeastern University.

We believe that Mr. Buckley is qualified to serve on our board of directors due to his experience working with public and private companies in our industry on corporate finance and accounting matters.

2012
Class I Directors (present term expires in 2020)

Bruce L. A. Carter, Ph.D.

Age: 75

Bruce L.A. Carter, Ph.D.,has served on our Board of Directors since November 2013 and as ournon-executive Chairman of the Board since December 2015. Dr. Carter is an Affiliate Professor in the Department of Biochemistry at the University of Washington, Seattle, Washington since 1986. He served as Executive Chairman of Immune Design Corp., a privately held biotechnology company, from November 2009 to November 2011 and he served as a director from 2000 to January 2009. From 1998 to 2009, Dr. Carter served as President and Chief Executive Officer of ZymoGenetics, Inc., a publicly-held biotechnology company, and as its Chairman of the Board from 2005 until it was acquired by Bristol-Myers Squibb in October 2010.2013

From 1994 to 1998, Dr. Carter was the Chief Scientific Officer of Novo Nordisk, a publicly-held pharmaceutical company. Previously he held positions in research at ZymoGenetics and G.D. Searle & Co. Ltd. Dr. Carter serves as a director of Dr. Reddy’s Laboratories Limited, a publicly-held pharmaceutical company, and Mirati Therapeutics, a publicly-held biopharmaceutical company. Dr. Carter holds a Ph.D. in microbiology from Queen Elizabeth College, University of London and a B.Sc. with Honors in botany from the University of Nottingham, England.

We believe that Dr. Carter is qualified to serve on our board of directors due to his business and scientific experience as a pharmaceutical executive in Europe and the United States and as chief executive officer of a biotechnology company, in addition, to his experience as a director of several companies in our industry.

Jay R. Luly, Ph.D.

Age: 62

Jay R. Luly, Ph.D., has served as our President and Chief Executive Officer and as a member of our board of directors since July 2003. Prior to joining Enanta, Dr. Luly was an Entrepreneur in Residence at Oxford Bioscience Partners. Before joining Oxford in March 2002, Dr. Luly held the positions of Senior Vice President, Research and Development Operations and Senior Vice President, Discovery Strategy and Operations at Millennium Pharmaceuticals following Millennium’s merger with LeukoSite, Inc., where he had served as Senior Vice President, Drug Discovery and Preclinical Development. Prior to joining LeukoSite, he held a number of senior drug discovery positions at Abbott Laboratories from 1983 to 1997. Dr. Luly received a B.S. from the University of Illinois, Urbana/Champaign and a Ph.D. in synthetic organic chemistry from the University of California, Berkeley.

We believe that Dr. Luly is qualified to serve on our board of directors due to his service as our President and Chief Executive Officer and his extensive knowledge of our company and industry.

2003
Class II Directors (present term expires in 2021)

George S. Golumbeski, Ph.D.

Age: 61

George S. Golumbeski, Ph.D.,has served as a member of our board of directors since February 2014. Dr. Golumbeski has served as President of GRAIL, Inc., a privately-held biotechnology company, since August 2018. From 2017 until April 2018, Dr. Golumbeski was the Executive Vice President for Innovation for Celgene Corporation, a biotechnology company, where he was previously Executive Vice President of Business Development since 2009, responsible for the full array of business development activities and focused primarily within the therapeutic areas of oncology and inflammation. From 2008 to 2009, Dr. Golumbeski served as the CEO of Nabriva Therapeutics AG. Prior to Nabriva, Dr. Golumbeski served as Vice President of Business Development, Licensing and Strategy for Novartis-Oncology. Earlier in his career, Dr. Golumbeski held senior positions at Elan Pharmaceuticals and at Schwarz Pharma. He currently serves on the board of directors of MorphoSys AG, a public biotechnology company. Dr. Golumbeski received a BA in biology from the University of Virginia and a Ph.D. in genetics from the University of Wisconsin-Madison.

 

We believe that Dr. Golumbeski is qualified to serve on our board of directors due to his experience in business development and drug development as an executive in the biotechnology and pharmaceutical industries.

2014

Kristine Peterson

Age: 5961

Kristine Petersonhas served as a member of our board of directors since September 2017. Ms. Peterson has over 2530 years of senior executive experience in commercial and business leadership roles in the pharmaceutical and biotechnology industry. From 2009 to 2016, Ms. Peterson served as Chief Executive Officer of Valeritas, Inc., a commercial-stage medical technology company where, under her leadership, the organization evolved from a research stage company to a commercial enterprise. Previously she held executive global marketing and commercial roles at Johnson & Johnson from 2004 to 2009, most recently as Company Group Chair, Biotech Sector, where she was responsible for commercial, R&D, and biologics manufacturing for biotech, oncology, immunology and cell therapy. From 2003 to 2004, she served as Senior Vice President, Commercial Operations for Biovail Corporation and President of Biovail Pharmaceuticals. Earlier in her career, she spent 20 years at Bristol-Myers Squibb Company in senior sales and marketing roles of increasing responsibility in a broad range of therapeutic areas that included Cardiovascular, Metabolic, Anti-infective, Virology, Neuroscience, Immunology/Inflammation, Pulmonary, and Oncology. Ms. Peterson currently serves on the Boards of Directors of Amarin Corporation plc, ImmunoGen, Inc., and Paratek Pharmaceuticals, Inc. and pSivida Corp., all of which are public biopharmaceutical companies. She received a Master of Business Administration and a Bachelor of Science from the University of Illinois at Urbana-Champaign.

 

We believe that Ms. Peterson is qualified to serve on our board of directors due to her executive management and sales and marketing experience in large pharmaceutical companies and smaller biotechnology companies and her other public company board experience.

2017

Terry C. Vance

Age: 6264

Terry C. Vancehas served as a member of our board of directors since June 2011. From June 2013 until November 2018, Mr. Vance was Chief Business Officer of BioMotiv, LLC, a drug development company affiliated with The Harrington Project. Until January 2018, Mr. Vance was a Managing Member of EGS Healthcare, a late-stage venture capital fund that heco-founded in 2000. Before starting EGS Healthcare, Mr. Vance was a founding partner in Eagle Advisors, which provided strategic advice to emerging biotechnology companies. Prior to Eagle, Mr. Vance was an investment banker, first with Salomon Brothers and then with Goldman Sachs, where he was a vice president in the Capital Markets Division. Mr. Vance received an AB from Princeton University and an MBA from Stanford University.

2011

 

We believe that Mr. Vance is qualified to serve on our board of directors due to his business and financial experience as a venture capital investor and investment banker in our industry.

2011

8


Class III Directors (present term expires in 2022)

Lesley Russell, MBChB, MRCP

Age: 60

Lesley Russell, MBChB, MRCP, was elected to our board of directors in November 2016. Dr. Russell served as Chief Medical Officer of Innocoll Holdings Plc., a public biotechnology company, from April 2016 until November 2017, prior to which Dr. Russell served as Chief Operating Officer and Chief Medical Officer of TetraLogic Pharmaceuticals, another public biotechnology company, from August 2013. Dr. Russell was a medical executive with Cephalon, Inc. from January 2000 to 2011, most recently as Executive Vice President and Chief Medical Officer from September 2006 until October 2011, when Cephalon was acquired by Teva Pharmaceuticals. Dr. Russell served as a Senior Vice President and Global Head, Research and Development for Global Branded Products from the acquisition until July 2012. Dr. Russell previously held positions in medical research at US Bioscience, Eli Lilly and Amgen. Dr. Russell is an independent director of Imugene Limited, an Australian public biotechnology company, Chimeric Therapeutics Limited, an Australian public biotechnology company, and Scopus Biopharma, a public biotechnology company. Dr. Russell holds a Bachelor of Medicine, Bachelor of Surgery (MBChB) from the University of Edinburgh and is a member of the Royal College of Physicians (MRCP), UK.

We believe that Dr. Russell is qualified to serve on our board of directors due to her business and drug development experience, her service on other public company boards and her knowledge of our industry.

2016

Mark G. Foletta,

Age 59

Mark G. Foletta was elected to our board of directors in June 2020. Mr. Foletta had been the Chief Financial Officer and Executive Vice President of Tocagen, Inc., a publicly-traded biotechnology company, from February 2017 until its merger with Forte Biosciences in June 2020. Mr. Foletta previously served as Senior Vice President, Finance and Chief Financial Officer of Amylin Pharmaceuticals, Inc., a publicly traded pharmaceutical company, from March 2006 through Amylin’s acquisition by Bristol Myers-Squibb Company in August 2012, and as Vice President, Finance and Chief Financial Officer of Amylin from 2000 to 2006. Previously, Mr. Foletta held a number of management positions with Intermark, Inc. and Triton Group Ltd. from 1986 to 2000 and served as an Audit Manager with Ernst & Young. From August 2015 to July 2016, Mr. Foletta served as the interim CFO of Biocept, Inc., a public diagnostics company. Mr. Foletta is an independent director of DexCom, Inc., a public medical device company where he also serves as Lead Director, and AMN Healthcare Services, Inc., a public healthcare services company. Mr. Foletta received a B.A. in Business Economics from the University of California, Santa Barbara.

We believe that Mr. Foletta’s considerable audit and financial experience in the biotechnology and healthcare sectors qualifies him to serve on our board of directors.

9


Class I Directors (present term expires in 2023)

Bruce L. A. Carter, Ph.D.

Age: 77

Bruce L.A. Carter, Ph.D., has served on our Board of Directors since November 2013 and as our non-executive Chairman of the Board since December 2015. Dr. Carter is an Affiliate Professor in the Department of Biochemistry at the University of Washington, Seattle, Washington since 1986. He served as Executive Chairman of Immune Design Corp., a privately held biotechnology company, from November 2009 to November 2011 and he served as a director from 2000 to January 2009. From 1998 to 2009, Dr. Carter served as President and Chief Executive Officer of ZymoGenetics, Inc., a public biotechnology company, and as its Chairman of the Board from 2005 until it was acquired by Bristol-Myers Squibb in October 2010.

From 1994 to 1998, Dr. Carter was the Chief Scientific Officer of Novo Nordisk, a public pharmaceutical company. Previously he held positions in research at ZymoGenetics and G.D. Searle & Co. Ltd. Dr. Carter serves as a director of Dr. Reddy’s Laboratories Limited, a public pharmaceutical company, and Mirati Therapeutics, a public biopharmaceutical company. Dr. Carter holds a Ph.D. in microbiology from Queen Elizabeth College, University of London and a B.Sc. with Honors in botany from the University of Nottingham, England.

We believe that Dr. Carter is qualified to serve on our board of directors due to his business and scientific experience as a pharmaceutical executive in Europe and the United States and as chief executive officer of a biotechnology company, in addition, to his experience as a director of several companies in our industry.

Jay R. Luly, Ph.D.

Age: 64

Jay R. Luly, Ph.D., has served as our President and Chief Executive Officer and as a member of our board of directors since July 2003. Prior to joining Enanta, Dr. Luly was an Entrepreneur in Residence at Oxford Bioscience Partners. Before joining Oxford in March 2002, Dr. Luly held the positions of Senior Vice President, Research and Development Operations and Senior Vice President, Discovery Strategy and Operations at Millennium Pharmaceuticals following Millennium’s merger with LeukoSite, Inc., where he had served as Senior Vice President, Drug Discovery and Preclinical Development. Prior to joining LeukoSite, he held a number of senior drug discovery positions at Abbott Laboratories from 1983 to 1997. Dr. Luly received a B.S. from the University of Illinois, Urbana/Champaign and a Ph.D. in synthetic organic chemistry from the University of California, Berkeley.

We believe that Dr. Luly is qualified to serve on our board of directors due to his service as our President and Chief Executive Officer and his extensive knowledge of our company and industry.

Recommendation

We recommend a vote “FOR” each of our two Class IIIII director nominees.

10


PROPOSALPROPOSAL 2

AMENDMENT TO 2019 EQUITY INCENTIVE PLAN

We are asking stockholders to approve a new equity planan amendment to replace the existing 2012 Equity Incentive Plan, which we refer to herein as the 2012 Equity Plan. The newour 2019 Equity Incentive Plan, which we refer to herein as the 2019 Equity Plan, will provide 1,600,000 new shares of common stock for equity awards to our employees, directors and consultants, in addition to any shares still available, or that may hereafter become available through forfeitures of prior equity awards, under the 2012 Equity Plan and its predecessor, the 1995 Equity Incentive Plan. Approval of the 2019 Equity Plan will also terminate theincrease so-called “evergreen provision”, which was a feature of our 2012 Equity Plan, that provided for automatic annual increases to the number of reserved shares. If Proposal 2 is approved by the requisite voteshares of stockholders, the Company intends to register subsequently the additional sharesour common stock reserved for issuance under the 2019 Equity Incentive Planplan by filing a registration statement onForm S-8.950,000 shares.  

Reasons for Adopting a New Plan and for Seeking Stockholder Approval

Equity Awards are a Key Part of our Compensation Program for Employees Generally

Our Compensation Committee believes that equity compensation has been, and will continue to be, a critical component of our compensation program because it develops a culture of ownership among our employees and aligns their interests with the interests of our stockholders. Unlike many companies, we have a practice of granting equity-based awards broadly throughout our organization, believing that we will succeed if all our employees feel invested in us, our business and our future. From January 2013September 30, 2018 to December 15, 2018,September 30, 2020, we have almost tripledincreased our employee headcount (from 39115 employees to 115)141). In 2019,2021, we anticipate that we will continue to build our research and development team with plans to hire approximately 40 additional employees to support clinical development of our most advanced compounds. To date, we have successfully competed for top talent, often in direct competition with much larger pharmaceutical companies with greater resources, in part because of our use of equity-based compensation. In addition, we have to compete with other biotechnology companies, all of which use equity-based compensation as a key component of their compensation programs. We believe that equity awards are central to our employment value proposition and are necessary for us to continue competing for top talent as we grow.

As of December 15, 2018, after the annual addition under the “evergreen provision” on October 1, 2018 and the aggregate annual equity awards for year end 2018 had been determined,31, 2020, there were 469,463539,087 shares available for grant under the 20122019 Equity Plan. As part of the proposed 2019 Equity Plan, we are proposing to terminate the “evergreen provision. Accordingly, without the proposed addition to the reserve in the 2019 Equity Plan, and assuming we would otherwise terminate the “evergreen provision” of the 2012 Equity Plan (If the 2019 Equity Plan is not approved by stockholders at the 2019 annual meeting, the 2012 Equity Plan will remain in place with its “evergreen provision” still operative.), our ability to provide equity incentives for our planned new hires, as well as our existing employees and management team, would be severely limited. In turn, this would place us at a competitive disadvantage because our ability to attract, motivate and retain key personnel would be compromised during a critical growth period.

Our Equity Program is Designed to Incentivize Performance

As noted above, our broad-based equity program generally provides for stock option awards to all employees, which awards are designed to incentivize performance because no value is created unless our stock price increases from the date the options are granted. We grant stock options to new employees that are subject to 25% vesting on the first anniversary of employment with the balance vesting quarterly over the subsequent three years. In addition, we provide annual awards of stock options to all employees that are subject to quarterly vesting over four years from the date of grant.  In the most recent annual equity awards to our employees, which were made in November 2020 during the first quarter of our 2021 fiscal year, our Compensation Committee chose to grant a portion of the annual equity award as restricted stock units that are subject to annual vesting over four years from the date of grant.  The number of restricted stock units was determined by reducing the number of stock options by one third and then calculating the Black-Scholes value of the shares eliminated from the option awards and dividing that quotient by a 30-day average of the equity value of our common stock.

In the case of our management team, the Compensation Committee has made awards of stock options, and most recently restricted stock units, in line with awards to our other employees described above, as well as performance share units. The performance share units are divided into

two types with one half, the PSUs, tied to corporate goals and one half, the rTSRUs, tied to relative stock performance. Specifically, the PSUs are subject to research and development goals based on advancement of our priorityclinical programs in NASH/PBC, RSV, HCV and HCV;NASH and our other earlier stage research; and the rTSRUs are based on the relative performance of our common stock against the other component companies in the NASDAQ Biotech Index, or ^NBI, over the same60-day calendar periods two years apart, with no units vesting unless our stock is in at least the 65th65th percentile of component companies at the end of the performance period.period and there is an absolute increase in our stock value. The performance share units can expire unvested or vest in an amount up to 200% (150% for unit awards granted since 2017)150% of the target number of units, depending on the company’scompany's performance.

Our Compensation Committee believes that the program of stock options and performance units provides management and our employees appropriate incentives to build the value of our company.

We Have Managed Our Equity Burn Rate Efficiently

In settingdetermining the proposed number of new shares to be reservedadded to the reserve for issuance under the 2019 Equity Plan and for which stockholder approval is being sought, the Compensation Committee considered the historical amounts of common stock underlying equity awards granted by the Company in the past three years and our projections for the coming year based on the Company’sCompany's current employee headcount.headcount and projected additions. In our fiscal years 2016, 20172018, 2019 and 2018,2020, the Company made equity awards, including a targeted number of shares reserved for

11


performance-based unit awards, representing a total of 564,930, 814,079655,695, 694,300 and 655,695875,084 shares, respectively. The weighted average numbers of shares of our common stock outstanding in 2016, 20172018, 2019 and 20182020 were 18,928,641, 19,065,96319,254,736, 19,583,625 and 19,254,73619,940,376 shares, respectively.

The Company’sfollowing table sets forth information regarding historical awards granted for the 2018 through 2020 period, and the corresponding annual net burn rate, which is defined as the number of shares covered by awards granted, net of forfeitures, divided by the weighted-average number of shares of common stock outstanding for that year, for each of the last five fiscal years:

 

 

Fiscal Year Ended September 30,

 

Share Element

 

2020

 

 

2019

 

 

2018

 

Time-based Stock Options and Restricted Stock Units Granted, Net of Forfeitures

 

 

619,832

 

 

 

560,926

 

 

 

553,226

 

Shares Reserved for Performance-Based Full Value Unit Awards Granted, at Target, Net of Forfeitures

 

 

33,456

 

 

 

22,500

 

 

 

44,800

 

Total Time-Based Awards Granted and Performance-Based Awards Granted

 

 

653,288

 

 

 

583,426

 

 

 

598,026

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Weighted-Average Common Shares Outstanding During the Fiscal Year

 

 

19,940,376

 

 

 

19,583,625

 

 

 

19,254,736

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Annual Net Burn Rate

 

 

3.3

%

 

 

3.0

%

 

 

3.1

%

3-Year Average Net Burn Rate

 

 

3.1

%

 

 

 

 

 

 

 

 

Without deducting forfeitures, our three-year average burn rate is 3.55%, including a burn rate of 3.41% in 2018. The reduction infor the burn rate in 2018 occurred despite the fact that during thefiscal 2018-2020 period from March 2013 to December 15, 2018, we almost tripled our employee headcount (from 39 employees to 115)was 3.8%.

Our Equity Award Overhang Reflects 7+ Years Without Dilutive Equity Financings

In addition,making its determinations, the Compensation Committee also considered the total amount of stock options and other equity awards outstanding under existing grants. Weawards. As of December 31, 2020, we had outstanding equity awards covering a total of 3,310,804 equity awards as of December 15, 20184,090,794 shares (commonly referred to as the “overhang”), consisting of stock options to purchase a total of 3,063,3033,789,348 shares, restricted stock units for 108,701123,046 shares, and performance unit awards targeting a total 138,800 shares, which in the aggregate represent approximately 17%178,400 shares. Our overhang is higher than many of our outstanding shares as of that date. Our burn rate and overhang are calculated as percentages of our outstanding shares of common stock and may be higher than some of our peers primarily due to the fact that we have not issued any shares of our common stock in an equity financing since the closing of our IPO in March 2013. Most biotechnology companies in that period of time would have done several rounds of follow-on equity financings, substantially reducing the percentage of shares represented by outstanding equity awards. In Enanta’s case this dilution was avoided because we have received an aggregate of $915 million in milestone payments and royalties on sales of products containing our HCV protease inhibitors since our 2013 IPO and we had $419 million in our cash and cash equivalent reserves at September 30, 2020.

The Proposed Increase Will Enable Needed Recruitment and Retention into 2022

After a review of our historical practices and in the context of our current and expected future growth and based on the recommendation of the Compensation Committee has determined that the proposed increase of 950,000 shares, which represents the equivalent of 4.7% of our shares of common stock outstanding as of December 31, 2020, is appropriate to cover our anticipated requirements for recruitment of new employees and retention of our personnel until at least the 2022 annual meeting of stockholders. The proposed increase is made in the context of our need to recruit more senior level employees in chemistry, manufacturing and controls (“CMC”), clinical development, medical affairs and business development as our clinical-stage pipeline expands and advances into larger clinical trials. The Compensation Committee believes that the proposed share reserve under the 2019 Equity Plan, in addition to the shares available undershare reserve is essential to the 2012 Equity Plan, would facilitate the Company’sCompany's ability to continue to grant equity incentives for at least the next two years,year, which is vital to our efforts to attract and retain the highly skilled individuals required to support our continued growth in the extremely competitive labor markets in which we compete.

The closing price of our common stock on the Nasdaq Global Select Market on December 14, 201831, 2020 was $73.76$42.10 per share, compared to $31.88 on December 15, 2016 and $17.18 at the close of our first day of trading in March 2013.share.  Based solely on the closing price of our common stock on December 14, 2018 of $73.76 per share,31, 2020, the aggregate intrinsic value of the proposed additional 1,600,000950,000 shares of common stock, which would be newly reserved for issuance under the 2019 Equity Plan, is $118,016,000.$39,995,000.

12


Stockholder Approval Requirements

Approval of the proposed amendment to the 2019 Equity Plan by our stockholders is required under the listing rules of the Nasdaq Stock Market. Stockholder approval will also ensure favorable federal income tax treatment for any awards of incentive stock options that may be made under Section 422 of the Internal Revenue Code of 1986, as amended (the “Code”"Code").

General Description of 2019 Equity Plan

The purpose of the 2019 Equity Plan is to attract and retain employees, directors and consultants and to provide an incentive for these individuals to achieve long-range performance goals. If approved, theThe 2019 Equity Plan will permitpermits us, under the direction of the Compensation Committee, to grant equity awards to our employees, directors and consultants, including incentive andnon-statutory stock options, stock appreciation rights, restricted stock, restricted stock units and other stock-based and cash-based awards.  Approximately 115Under the 2019 Plan to date, we have awarded only non-statutory stock options, time-based restricted stock units, performance share units and relative total stockholder return units.

As of December 31, 2020, 139 employees and 6six non-employee directors will bewere eligible to participate in the 2019 Equity Plan.As of that date, a total of 1,471,265 shares were reserved under the 2019 Equity Plan for outstanding stock options, and 123,046 shares were reserved for outstanding restricted stock unit awards. In addition, as of that date a total of 178,400 shares were reserved for potential issuance pursuant to performance-based and market-based stock unit awards. The Company has issued no shares of common stock upon option holders exercising options or vesting of restricted stock or performance stock units awarded under the 2019 Equity Plan through December 31, 2020. Additionally, while no further awards have been made under our 2012 Equity Incentive Plan, referred to as our 2012 Equity Plan since February 26, 2019, shares subject to options that were granted under that plan and that are forfeited or that expire unexercised are then added to the shares available for issuance under the 2019 Equity Plan. Similarly, no further awards were made under our Amended and Restated 1995 Equity Incentive Plan, referred to as the 1995 Equity Plan, after our initial public offering in March 2013, and shares subject to options that were granted under that plan and that are forfeited or that expire unexercised are then added to the shares available for issuance under the 2019 Equity Plan. To date, we have had 247,087 shares added to the 2019 Equity Plan from such forfeitures, in addition to the 361,855 shares remaining reserved for issuance under the 2012 Equity Plan, which were added to the 2019 Equity Plan upon its approval by our stockholders. There remain 158,241 shares subject to outstanding options awarded under the 1995 Equity Plan, which have exercise prices ranging from $11.77 to $14.18 per share and 2,159,842 shares subject to outstanding options awarded under the 2012 Equity Plan, which have exercise prices ranging from $20.56 to $121.13 per share. Of those shares, 1,156,597 are subject to stock options with exercise prices exceeding $42.10.

Also as of December 31, 2020, outstanding options awarded under the 2019 Equity Plan had exercise prices ranging from $41.20 per share to $103.85 per share. The weighted average exercise price of all outstanding options under the plan is $54.77 per share, and those options have a term of ten years, and as of December 31, 2020, had a weighted average duration of nine years. As the amount of any awards under the 2019 Equity Plan is within the Compensation Committee’s discretion, total awards that may be granted for a fiscal year are not determinable until completion of the year.

The following section provides an overview oftable sets forth shares underlying awards granted under the proposed 2019 Equity Plan and unexercised or not settled, as the case may be, as of the close of business on September 30, 2020:

13


Total Awards Under the 2019 Equity Incentive Plan

Number of Shares of Common Stock Underlying Options/Units

Current executive officers:

Jay R. Luly, Ph.D.

131,700

(a)

Yat Sun Or, Ph.D.

38,200

(b)

Nathalie Adda, M.D.

38,200

(c)

Paul J. Mellett

38,200

(d)

Nathaniel S. Gardiner, J.D.

38,200

(e)

Current executive officers as a group (6 persons)

284,500

(f)

Current non-executive officer directors as a group (5 persons)

92,000

Other Enanta employees as a group

561,991

Total Awards through September 30, 2020

938,491

(f)

The numbers of performance-based PSU and rTSRU unit awards included in this table are the target numbers of shares subject to the approvalawards. Actual performance may result in no shares being issued under a stock unit award or up to 1.5x that target number of our stockholdersshares being issued. Restricted stock units with time-based vesting are included at the total number of shares subject to the awards.

(a)

Includes a total of 21,700 shares subject to performance-based unit awards, which will only vest upon achievement of specified milestones over the corresponding performance period.

(b)

Includes a total of 8,200 shares subject to performance-based unit awards, which will only vest upon achievement of specified milestones over the corresponding performance period.

(c)

Includes a total of 8,200 shares subject to performance-based unit awards, which will only vest upon achievement of specified milestones over the corresponding performance period.

(d)

Includes a total of 8,200 shares subject to performance-based unit awards, which will only vest upon achievement of specified milestones over the corresponding performance period.

(e)

Includes a total of 8,200 shares subject to performance-based unit awards, which will only vest upon achievement of specified milestones over the corresponding performance period.

(f)

Includes a total of  54,500 shares subject to performance-based unit awards, which will only vest upon achievement of specified milestones over the corresponding performance period.

Because the granting of awards under the 2019 annual meeting.Equity Plan is discretionary, we cannot now determine the number or type of awards to be granted in the future to any particular person or group if the amendment to the 2019 Equity Plan is approved.

Administration and Eligibility

Awards are made by the Compensation Committee, which has been designated by our Board of Directors to administer the 2019 Equity Plan. Subject to certain limitations, the Compensation Committee may delegate to one or more of our executive officers the power to make awards to participants who are not subject to Section 16 of the Securities Exchange Act of 1934 and are not “executive officers” for purposes of the Securities Exchange Act of 1934, as amended.The Compensation Committee has authorized our Chief Executive Officer to make awards to non-executive employees within parameters approved by the Committee.

The Compensation Committee will administeradministers the 2019 Equity Plan and determinedetermines the terms and conditions of each equity award to our executive officers and directors, including the number of shares subject to the award, the exercise price and the form of payment of the exercise price for any stock option, the vesting conditions of the award and the terms of any withholding of shares or other provisions to satisfy tax withholding requirements for the award.

14


Types of Awards

The 2019 Equity Plan provides for the following categories of awards:

Stock Options.The Compensation Committee may grant options to purchase shares of common stock that are either incentive stock options, or ISOs, eligible for the special tax treatment described below, or nonstatutory stock options. No option may have an exercise price that is less than the fair market value of the common stock on the date of grant or a term of more than ten years. An option may be exercised by the payment of the option price in cash or with such other lawful consideration as the Compensation Committee may determine, including by delivery of shares of common stock owned by the optionholder, by a broker-assisted cashless exercise, or by Enanta retaining shares otherwise issuable pursuant to the option.

Restricted Stock.Our Compensation Committee may grant shares of common stock that are only earned if specified conditions, such as a completing a term of employment or satisfyingpre-established performance goals, are met and that are otherwise subject to forfeiture. Shares of restricted stock may not be sold, transferred or otherwise encumbered until earned, unless the Compensation Committee provides otherwise.

Restricted Stock Units.Our Compensation Committee may grant units that represent the right to receive shares of our common stock, subject to such terms, restrictions, conditions, performance criteria, vesting requirements, settlement terms, and payment rules, if any, as the Committee shall determine.

Unrestricted Stock.Our Compensation Committee may grant shares of common stock that are not subject to restrictions or forfeiture.

Stock Appreciation Rights.Our Compensation Committee may grant stock appreciation rights, or SARs, where the participant receives cash, shares of common stock, or other property, or a combination thereof, as determined by the Compensation Committee, equal in value to the difference between the exercisemeasurement price of the SAR and the fair market value of the common stock on the date of exercise. SARs may be granted in tandem with options (at or after award of the option) or alone and unrelated to an option. SARs in tandem with an option shall terminate to the extent that the related option is exercised, and the related option shall terminate to the

extent that the tandem SARs are exercised. SARs granted in tandem with options shall have an exercisea measurement price not less than the exercise price of the related option. SARs granted alone and unrelated to an option shall have an exercisea measurement price not less than 100% of the Fair Market Value of the common stock on the date of award may be granted ator on such exercise pricesfuture date as the Committee may determine.

Stock Dividends and Stock Splits

If our common stockdetermine is subdivided or combined into a greater or smaller number of shares or if we issue any shares of common stock as a stock dividend, the number of shares of our common stock thereafter deliverable upon the exercise of an outstanding option or upon issuance under another type of award shall be appropriately increased or decreased proportionately, and appropriate adjustments shall be made in the per share purchase price and performance goals applicable to performance-based awards, if any, to reflect such subdivision, combination or stock dividend.

Other Dividends

Dividends (other than stock dividends as described above) may accrue but are not payable prior to the time, and only to the extent that, the underlying shares have vested or restrictions or rights to reacquire shares subject to awards have lapsed.

Corporate Transactions

Upon a merger, consolidation or other reorganization event, our Board of Directors, may, in its sole discretion, take any one or more of the following actions pursuant to the 2019 Equity Plan, as to some or all outstanding awards:

provide that all outstanding options shall be assumed or substituted by the successor corporation;

upon written notice to a participant, provide that the participant’s unexercised options will terminate immediately prior to the consummationgrant date of such transaction unless exercised by the participant;

provide that outstanding awards shall become realizable or deliverable, or restrictions applicable to an award will lapse, in whole or in part, prior to or upon the merger or reorganization event;

in the event of a merger pursuant to which holders of our common stock will receive a cash payment for each share surrendered in the merger, make or provide for a cash payment to the participants equal to the difference between the merger price times the number of shares of our common stock subject to vested outstanding options, and the aggregate exercise price of all such outstanding options, in exchange for the termination of such options; and

with respect to stock grants, and in lieu of any of the foregoing, our Board of Directors or an authorized committee may provide that, upon consummation of the transaction, each outstanding stock grant shall be terminated in exchange for payment of an amount equal to the consideration payable upon consummation of such transaction to a holder of the number of shares of common stock comprising such award (to the extent such stock grant is no longer subject to any forfeiture or repurchase rights then in effect or, at the discretion of the Board of Directors or an authorized committee, all forfeiture and repurchase rights being waived upon such transaction).

Amendment and Termination

The 2019 Equity Plan may be amended by our stockholders. It may also be amended by our Board of Directors, provided that any amendment approved by our Board which requires stockholder approval (1) under the rules of the Nasdaq Stock Market, (2) in order to ensure favorable federal income tax treatment for any incentive stock options under Section 422 of the Code, or (3) for any other reason, is subject to obtaining such stockholder approval. However, no such action may adversely affect any rights any outstanding awards without the holder’s consent. Other than in connection with stock dividends, stock splits and corporate transactions, as

summarized above, (i) the exercise price of an option may not be reduced, (ii) an option may not be canceled in exchange for a replacement option having a lower exercise price, or for another award or for cash, and (iii) no other action may be taken that is considered a direct or indirect “repricing,” in each case without stockholder approval.

Duration of the 2019 Equity Plan

The 2019 Equity Plan will become effective upon approval of the plan by vote of our stockholders, which is scheduled for February 28, 2019, and will expire by its terms after the expiration of ten years from the anniversary of the date of the original approval by our stockholders unless extended by a subsequent vote of our stockholders approving an increase in the maximum number of shares that may be issued under the plan. In the event of any such subsequent approval, the expiration date of the 2019 Equity Plan shall automatically reset to the date ten years from the date of the latest subsequent approval. No awards may be made after termination of the 2019 Equity Plan, although previously granted awards may continue beyond the termination date in accordance with their terms.award.

Federal Income Tax Consequences Relating to Stock Options and Restricted StockAwards

Incentive Stock Options.An optionee does not realize taxable income upon the grant or exercise of an incentive stock option, known as an ISO, under the 2019 Equity Plan. If no disposition of shares issued to an optionee pursuant to the exercise of an ISO is made by the optionee within two years from the date of grant or within one year from the date of exercise, then (a) upon sale of such shares, any amount realized in excess of the option price (the amount paid for the shares) is taxed to the optionee as a long-term capital gain and any loss sustained will be a long-term capital loss and (b) no deduction is allowed to Enanta for Federal income tax purposes. The exercise of ISOs gives rise to an adjustment in computing alternative minimum taxable income that may result in alternative minimum tax liability for the optionee.

If shares of common stock acquired upon the exercise of an ISO are disposed of prior to the expiration of thetwo-year andone-year holding periods described above, referred to as a disqualifying disposition, then (a) the optionee realizes ordinary income in the year of disposition in an amount equal to the excess (if any) of the fair market value of the shares at exercise (or, if less, the amount realized on a sale of such shares) over the option price thereof and (b) Enanta is entitled to deduct this amount. Any further gain realized is taxed as a capital gain, which will be long-term if the shares were held for more than one year following exercise and does not result in any deduction to Enanta. A disqualifying disposition in the year of exercise will generally avoid the alternative minimum tax consequences of the exercise of an ISO.

Non-statutory Stock Options.No income is realized by the optionee at the time anon-statutory option is granted. Upon exercise, (a) ordinary income is realized by the optionee in an amount equal to the difference between the option price and the fair market value of the shares on the date of exercise and (b) Enanta receives a tax deduction for the same amount. Upon disposition of the shares, appreciation or depreciation after the date of exercise is treated as a capital gain or loss, which will be short-term or long-term depending upon how long the shares have been held and will not result in any deduction by Enanta.

15


Restricted Stock.Awards of restricted stock that arenon-transferable and subject to forfeiture are generally not taxable to the recipient until the shares vest. When the shares vest, the recipient realizes compensation income equal to the difference between the amount paid for the shares and their fair market value at the time of the vesting, and we are entitled to a corresponding deduction. The tax is payable for the year in which the vesting occurs, regardless of whether the shares are sold at that time. Upon subsequent disposition of the shares, any appreciation or depreciation is treated as short-term or long-term capital gain or loss, depending on the length of time the recipient has held the shares after the date on which the shares vested.

Instead of being taxed when the shares vest, a recipient may elect to be taxed in the year the shares are awarded by filing a “Section 83(b) election” with the Internal Revenue Service within 30 days after issuance of

the restricted shares. The recipient then realizes compensation income in the year of the award equal to the difference between the amount paid for the shares and their fair market value at the time of issuance, and Enanta is entitled to a corresponding deduction at that time. Upon subsequent disposition of the shares, any appreciation or depreciation is treated as short-term or long-term capital gain or loss, depending on the length of time the recipient has held the shares since the date of receipt of the shares.

Unrestricted Stock.Generally, a recipient will be taxed at the time of the grant of the award. The fair market value of the shares at that time will be treated as ordinary income and Enanta is entitled to receive a tax deduction for the amount reported as ordinary income. Upon disposition of the shares, any appreciation or depreciation since the time of grant is treated as short-term or long-term capital gain or loss, depending on the length of time the recipient has held the shares.

Restricted Stock Units.A recipient does not realize taxable income upon the grant or vesting of a restricted stock unit. When a stock unit is settled, i.e. when the underlying share of common stock is issued to the recipient, the recipient realizes ordinary income in an amount equal to the fair market value of the shares distributed to settle the award, and Enanta is entitled to a tax deduction for such amount. If the award is settled in shares, then upon disposition of the shares any subsequent appreciation or depreciation is treated as short- or long-term capital gain or loss, depending on the length of time the recipient has held the shares since the date of settlement.

Internal Revenue Code Section 162(m) Limitation on Deductibility of Certain Equity Awards

After enactment of the Tax Cuts and Jobs Act of 2017, United States tax law generally does not allow publicly-held companies to obtain tax deductions for compensation of more than $1.0 million paid in any year to any of the chief executive officer, the chief financial officer and the next three highest paid executive officers, as well as any officer who was treated as a covered employee under Section 162(m) of the U.S. Internal Revenue Code of 1986, as amended, for any year beginning after December 31, 2016 (each, a “covered employee”). As a result, Enanta willis not be entitled to a compensation deduction with respect to awards under the 2019 Equity Plan to a covered employee to the extent the aggregate amount payable results in total compensation in excess of the $1.0 million limit.

The preceding summary is qualified in its entirety by reference to the full text of the 2019 Equity Plan, which is attached as Appendix A to this proxy statement.

Equity Compensation Plan Information

The following table provides information about the securities authorized for issuance under the Company’sCompany's equity compensation plans as of September 30, 2018:2020:

Equity Compensation Plan Information

Equity Compensation Plan Information

Equity Compensation Plan Information

 

 

Plan Category

  Number of securities
to be issued upon
exercise of
outstanding options,
warrants and rights
 Weighted average
exercise price of
outstanding
options, warrants
and rights
   Number of securities
remaining available
for future issuance
under equity
compensation plans
(excluding securities
reflected in column
(a))
 

 

Number of securities to be issued upon exercise of outstanding options, warrants and rights

 

 

 

Weighted average exercise price of

outstanding options, warrants

and rights

 

 

Number of securities remaining available for future issuance

under equity compensation plans (excluding securities reflected in column

(a))

 

 

  (a) (b)   (c) 

 

(a)

 

(b)

 

 

(c)

 

 

Equity compensation plans approved by security holders(1)

   2,871,464(2)   $33.47    436,840(3)  

Equity compensation plans approved by security holders (1)

 

3,399,475

 

 

(2

)

$

47.81

 

 

 

1,406,999

 

(3)(4)

Equity compensation plans not approved by security holders

     

Equity compensation plans not approved by security holders

 

 

 

 

 

 

 

 

 

 

 

  

 

    

 

 

Totals

   2,871,464    

 

 

3,399,475

 

 

 

 

 

 

1,406,999

 

 

(1)

Consists of the 2019 Equity Plan, the 2012 Equity Plan, the 1995 Equity Plan and our Employee Stock Purchase Plan.

16


(2)

(2)

Consists of shares of our common stock issuable upon exercise of outstanding options, restricted stock units and performance share units issued under the 2019 Equity Plan, the 2012 Equity Incentive Plan and the 1995 Equity Incentive Plan.

(3)

Consists of 1,220,999 shares of our common stock reserved for future issuance under the 20122019 Equity Plan and 186,000 shares reserved for issuance under our Employee Stock Purchase Plan. This does not include 582,637

(4)

As of December 31, 2020, after annual equity awards in the quarter then ended, only 539,087 shares of our common stock that were automatically added toremained available for future issuance under the 20122019 Equity Plan by its terms as of October 1, 2018.Incentive Plan.

New Plan Benefits Table

The issuance of any awards under the 2019 Equity Plan will be at the discretion of our Compensation Committee. Therefore, it is not possible to determine the amount or form of any award that will be granted to any individual in the future.

Proposed Approval of Additional Shares to be Reserved for Issuance under the 2019 Equity Plan

We are seeking stockholder approval of the increase in the number of shares of our common stock reserved for issuance under the 2019 Equity Plan by 950,000 shares.  If Proposal 2 is approved by the requisite vote of stockholders, the Company intends to register subsequently the additional shares reserved for issuance under the 2019 Equity Incentive Plan by filing a registration statement on Form S-8.

The preceding summary is qualified in its entirety by reference to the full text of the 2019 Equity Plan, before giving effect to this amendment, which has been filed with the SEC and is available on the SEC website at https://www.sec.gov/Archives/edgar/data/1177648/000156459019006792/enta-ex101_6.htm.  The full text of the 2019 Equity Plan is filed with the SEC as Appendix A to this proxy statement.

Vote Required

The affirmative vote of a majority of the shares represented in person or by proxy at the annual meeting and entitled to vote on this proposal will constitute the approval of the amendment to increase the number of shares of our common stock reserved for issuance under our 2019 Equity Plan.Plan by 950,000 shares. Abstentions and brokernon-votes will not be treated as votes cast for the purpose of determining the outcome of this proposal.

Recommendation

We recommend a vote “FOR”"FOR" the proposal to approve the amendment to the 2019 Equity Incentive Plan.

17


PROPOSALPROPOSAL 3

ADVISORY VOTE ON APPROVAL OF THE FREQUENCY OF HOLDING AN ADVISORY VOTE ON

THE COMPENSATION OF OUR NAMED EXECUTIVE OFFICERS

We are seeking your input with regard to the frequency of holding future stockholder advisory votes on the compensation of our named executive officers. {Based on the“say-on-frequency” votes of other companies in our industry, we believe an annual“say-on-pay” vote best meets the expectations of our stockholders. Therefore, we are recommending that future“say-on-pay” votes be conducted on an annual basis.

The proxy card provides stockholders with the opportunity to choose among three options for holding the advisory vote in future proxy statements:

Every year,

Every two years, or

Every three years.

The affirmative vote of a majority of the shares voted for this proposal will be the frequency approved, on an advisory basis, by our stockholders. However, because the vote on the frequency of holding future advisory votes on the compensation of our named executive officers is not binding, if none of the frequency options receives a majority vote, the option receiving the greatest number of votes will be considered the frequency preferred by our stockholders.

We understand that our stockholders may have different views as to what is the best approach for Enanta, and we look forward to hearing from our stockholders on this proposal.

Recommendation

We recommend that stockholders vote “FOR” the frequency of an advisory vote on executive compensation being every year.

PROPOSAL 4

ADVISORY VOTE TO APPROVE THE COMPENSATION PAID TO

OUR NAMED EXECUTIVE OFFICERS

We are providing our stockholders with the opportunity to cast an advisory(non-binding) vote on executive compensation, oralso known as a“say-on-pay” “say-on-pay” vote. Under Section 14AIn light of the Securities Exchange Actvote of 1934,our stockholders approving annual say-on-pay votes at our 2020 annual meeting of stockholders, we must holdintend to continue to seek this advisory vote at least once every three years thereafter.input on an annual basis.

Thesay-on-pay vote is anon-binding vote on the compensation paid to our named executive officers, as described elsewhere in this proxy statement under the heading“Executive Compensation,” and includes the “Compensation Discussion and Analysis,” the tabular disclosure regarding such compensation of our named executive officers and the accompanying narrative disclosure set forth elsewhere in this proxy statement. The Executive Compensation section describes our compensation philosophy and objectives, how we determine executive compensation, the elements of total compensation and the actual compensation of our named executive officers identified in that section. TheOur Compensation Committee and our Board believe that the policies and practices described in the “Compensation Discussion and AnalysisAnalysis” are effective in implementing our compensation philosophy and objectives and that the compensation of our named executive officers for 20182020 reflects and supports those policies and practices.

Thesay-on-pay vote is not binding on theour Compensation Committee or our Board. However, theour Compensation Committee and the Board will take into account the result of the vote when determining future executive compensation arrangements.

Recommendation

We recommend a vote “FOR” the proposal to approve, on an advisory basis, the compensation paid to our named executive officers, as described in this proxy statement.

PROPOSAL 54

RATIFICATION OF APPOINTMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

The firm of PricewaterhouseCoopers LLP, an independent registered public accounting firm, has audited our financial statements for each of the years ended September 30, 2018, 20172020, 2019 and 2016.2018. Our Audit Committee has appointed them to serve as our auditors for the fiscal year ending September 30, 2019.2021. Detailed disclosure of the audit and tax fees we paid to PricewaterhouseCoopers LLP in 20182020 and 20172019 may be found in the “Audit Fees” section of this proxy statement. Based on these disclosures and information in the Audit Committee Report provided elsewhere in this proxy statement, our Audit Committee is satisfied that PricewaterhouseCoopers LLP is sufficiently independent of management to perform its duties properly. Although not legally required to do so, our Board considers it desirable to seek, and recommends, stockholder ratification of our selection of PricewaterhouseCoopers LLP as our independent registered public accounting firm for fiscal year 2019.2021. If the stockholders fail to ratify our selection, the Audit Committee will reconsider whether or not to retain that firm. Even if the selection is ratified, the Audit Committee in its discretion may direct the appointment of a different independent registered public accounting firm at any time during the year if the Audit Committee determines that such a change would be in the best interest of Enanta and its stockholders.

Recommendation

We recommend a vote “FOR” ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm.

18


CORPORATE GOVERNANCEGOVERNANCE

Board and Committee Matters

Board Leadership and Independence.Our Board of Directors has determined that Bruce L.A. Carter, Ph.D.,Kristine Peterson and Terry Vance, as well as those director nominees and those directors continuing their terms after the 20192021 Annual Meeting, are independent directors as defined by applicable Nasdaq Stock Market standards governing the independence of directors, except thatdirectors. Jay R. Luly, Ph.D., our President and Chief Executive Officer, is not considered independent.

The Board of Directors sets company strategy and provides oversight and accountability for our Chief Executive Officer and management. Dr. Carter has served as ournon-executive Chairman of the Board since December 2015. Dr. Carter presides over meetings of the Board of Directors and provides guidance to our Chief Executive Officer. Dr. Luly continues to beis responsible for setting the strategic direction for our Company and theday-to-day leadership and performance of the Company. We believe that separation of our Board of Directors and executive leadership preserves the independence of these roles and maximizes performance.

Board Meetings and Committees.Our Board of Directors held 5six meetings during 2018,2020, and the independent directors held executive sessions at 4 of the meetings of the Board. During 2018,2020, each of the directors then in office attended at least 75% of the aggregate of all meetings of the Board of Directors and all meetings of the committees of the Board of Directors on which such director then served.

Continuing directors and nominees for election as directors in a given year are required to attend the annual meeting of stockholders, barring significant commitments or special circumstances. All of our directors then serving as directors attended our 20182020 annual meeting of stockholders, except for Dr. Carter, who had planned to attend but could not due to travel delays.stockholders.

Stockholder Communications.Any stockholder wishing to communicate with our Board of Directors, a particular director or the chair of any committee of the Board of Directors may do so by sending written correspondence to our principal executive offices, to the attention of the Chairman of the Board. All such communications will be delivered to the Board of Directors or the applicable director or committee chair.

During 2018,2020, our Board of Directors had three standing committees: Audit Committee, Compensation Committee and Nominating and Corporate Governance Committee.

Audit Committee.

Our Audit Committee’s responsibilities include:

appointing, approving the compensation of and assessing the independence of our registered public accounting firm;

overseeing the work of our registered public accounting firm, including through the receipt and consideration of reports from such firm;

reviewing and discussing with management and the registered public accounting firm our annual and quarterly financial statements and related disclosures;

monitoring our internal control over financial reporting, disclosure controls and procedures and code of business conduct and ethics;

overseeing our risk assessment and risk management policies;

establishing policies regarding hiring employees from the registered public accounting firm and procedures for the receipt and retention of accounting related complaints and concerns;

meeting independently with our registered public accounting firm and with our management;

reviewing and approving or ratifying any related person transactions; and

preparing the Audit Committee Report required by Securities and Exchange Commission, or SEC rules.

The members of our Audit Committee during 20182020 were Messrs. BuckleyFoletta and Vance and Dr.Drs. Russell and Carter, with Mr. BuckleyVance serving as Chair pro temof the committee.Audit Committee until Mr. Foletta joined the Board of Directors as Chairman of the Audit Committee in June 2020, whereupon Dr. Carter ceased to be a member of the Audit Committee. All members of our Audit Committee meet the requirements for

financial literacy under the applicable rules and regulations of the SEC and Nasdaq. Our Board has determined that Mr. Buckleyeach of Messrs. Foletta and Vance is an Audit Committeeaudit committee financial expert as defined under the applicable rules of the SEC and has the requisite financial sophistication as defined under the applicable rules and regulations of Nasdaq. Our Board has determined that each of and Dr. Russell and Messrs. BuckleyFoletta and Vance and Drs. Carter and Russell are independent under the applicable rules of Nasdaq and under the applicable rules of the SEC. The Audit Committee held 5five meetings during 2018.2020. The Audit Committee operates under a written charter that satisfies the applicable standards of the SEC and Nasdaq. A copy of the Audit Committee charter is available in the “Investors – Corporate Governance” section of the Company’s website atwww.enanta.com.

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Compensation Committee.

Our Compensation Committee’s responsibilities include:

annually reviewing and approving corporate goals and objectives relevant to the compensation of our chief executive officer;

reviewing and approving, or making recommendations to our board of directors with respect to, the compensation of our chief executive officer and our other executive officers;

overseeing an evaluation of our senior executives;

overseeing and administering our cash and equity incentive plans;

reviewing and making recommendations to our board of directors with respect to director compensation; and

reviewing and discussing annually with management our executive compensation disclosure, and theour Compensation Committee Report, required by SEC rules.

The members of our Compensation Committee during 20182020 were Drs. Carter and Golumbeski and Mr. Vance and Ms. Peterson. Dr. Golumbeski chairschaired our Compensation Committee.Committee until August 2020 at which point Ms. Peterson succeeded as chair pro tem. None of the members of our Compensation Committee has at any time been one of our officers or employees. None of our executive officers currently serves, or in the past fiscal year has served, as a member of the Board or Compensation Committee of any entity that has one or more executive officers on our Board or Compensation Committee. Each of the members of our Compensation Committee is independent under the applicable rules and regulations of Nasdaq and is a“non-employee “non-employee director” as defined in Rule16b-3 promulgated under the Exchange Act. TheOur Compensation Committee held 6seven meetings during 2018. The2020. Our Compensation Committee operates under a written charter adopted by the Board, which is available in the “Investors – Corporate Governance” section of our website atwww.enanta.com.

For more information regarding the authority of our Compensation Committee, the extent of delegation to our Compensation Committee, our processes and procedures for determining executive compensation and the role of executive officers and compensation consultants in determining or recommending the amount or form of compensation for directors and executive officers, please see “Executive Compensation – Compensation Discussion and Analysis” in this proxy statement.

Nominating and Corporate Governance Committee.

Our Nominating and Corporate Governance Committee’s responsibilities include:

identifying individuals qualified to become members of our board of directors;

recommending to our board of directors the persons to be nominated for election as directors and to each of our board’s committees;

reviewing and making recommendations to our board of directors with respect to our board leadership structure;

reviewing and making recommendations to our board of directors with respect to management succession planning;

developing and recommending to our board corporate governance principles; and

overseeing an annual self-evaluation by our board of directors.

The current members of our Nominating and Corporate Governance Committee are our independent directors, namely Drs. Carter, Golumbeski and Russell, Messrs. BuckleyFoletta and Vance and Ms. Peterson. Mr. Vance chairs the Nominating and Corporate Governance Committee. Each of the members of our Nominating and Corporate Governance Committee is an independent director under the applicable rules and regulations of Nasdaq relating to Nominating and Corporate Governance Committee independence. The Committee held two meetingsone meeting during 2018.2020. The Nominating and Corporate Governance Committee operates pursuant to a written charter, which is available in the “Investors – Corporate Governance” section of our website atwww.enanta.com.

The Nominating and Corporate Governance Committee considers candidates for Board membership suggested by its members and the Chief Executive Officer. In 2013 it also establishedIt typically establishes a subcommittee consisting of Messrs. Vance and Buckley (the “Nominating“Recruiting Subcommittee”) to work with an independent recruiting firm and Dr. Luly to help identify and recruit additional candidates, whichcandidates. This was the process that resulted in the recruitment of Drs. Carter, Golumbeski and Russell, Mr. Foletta and Ms. Peterson. Additionally, in selecting nominees for directors, the Nominating and Corporate Governance Committee will review candidates recommended by stockholders in the same manner and using the same general criteria as candidates recruited by the committee and/or recommended by the Board. Any stockholder who wishes to recommend a candidate for consideration by the committee as a nominee for director should follow the procedures described later in this proxy statement under the heading ��Stockholder“Stockholder Matters-Stockholder Recommendations for Director Nominations.” The NominatingRecruiting Subcommittee will also consider whether to nominate any person proposed by a stockholder in accordance with the provisions of our bylaws relating to stockholder nominations as described later in this proxy statement under the heading “Stockholder Matters-Deadline for Stockholder Proposals and Director Nominations.”

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This process used by the NominatingRecruiting Subcommittee in 2013recent years is likely to be the process for any future director searches. In 2013,Typically the NominatingRecruiting Subcommittee startedstarts the director search process by identifying a mix of types of experience and personal characteristics that the NominatingRecruiting Subcommittee consideredconsiders most valuable to complement the skills and experience of existing directors. Once the NominatingRecruiting Subcommittee hadhas identified prospective nominees,nominee candidates, the Subcommittee then mademakes an initial determination as to whether to conduct a full evaluation of theany candidate. This initial determination wasis based on the information provided to the Subcommittee in a report from the recruiting firm, as well as the Subcommittee’s own knowledge of the prospective candidate. The preliminary determinations wereare based primarily on the need for additional Board members to fill vacancies or expand the size of the Board and the likelihood that the prospective nominee could satisfy the evaluation factors described below. The Subcommittee then evaluatedevaluates the prospective nominees against the standards and qualifications set out in our Corporate Governance Guidelines, which include among others:

the extent to which the prospective nominee’s skills, experience and perspective add to the range of talent appropriate for the Board and whether such attributes are relevant to our business and industry;

the prospective nominee’s ability to dedicate the time and resources sufficient for the diligent performance of Board duties;

whether the prospective nominee meets the independence requirements and Audit Committee and Compensation Committee qualifications defined under applicable Nasdaq Stock Market standards and if appropriate, the Audit Committee financial expert requirements defined under applicable SEC rules and regulations; and

the extent to which the prospective nominee holds any position that would conflict with a director’s responsibilities to Enanta.

Although the Committee does not have a formal policy for considering diversity in identifying nominees for director, it has sought a variety of occupational and personal backgrounds on the Board in order to obtain a range of viewpoints, perspectives and skills.

If the NominatingRecruiting Subcommittee’s initial evaluation wasis positive, the members of the NominatingRecruiting Subcommittee each interviewedinterview the candidate. Upon completion of this evaluation and interview process, the NominatingRecruiting Subcommittee mademakes a recommendation to the full Board as to whether the candidate should be nominated by the Board and invitedinvites other directors to interview the candidate in person or by phone. The Board then determineddetermines whether to approve the nominee after considering the recommendation and report of the NominatingRecruiting Subcommittee.

In November 2018,2020, the Nominating and Corporate Governance Committee established a subcommittee (the “Nominating Committee”Subcommittee”) for the purpose of determining the director nominees for election at the 2019 annual meeting of stockholders.2021 Annual Meeting. The Nominating CommitteeSubcommittee consists of Mr. Vance, Ms. Peterson and Drs. Carter and Golumbeski, whoRussell and Mr. Foletta, all of whom are all independent directors. In December 2018,2020, the Nominating CommitteeSubcommittee approved the director nominees for election at the 2019 annual meeting.2021 Annual Meeting.

Risk Oversight.

The Board’s role in our risk oversight process includes receiving reports from time to time from the Audit Committee on areas of material risk to the Company, including operational, financial, legal and regulatory, and strategic and reputational risks.

Certain Relationships and Related Transactions

Policy on Related Person Transactions

Our Board of Directors has adopted a written Policy on Related Person Transactions that sets forth our policies and procedures for the reporting, review, and approval or ratification of each related person transaction. Our Audit Committee is responsible for implementing this policy and determining that any related person transaction is in our best interests. The policy applies to transactions and other relationships that would need to be disclosed in this proxy statement as related person transactions pursuant to SEC rules. In general, these transactions and relationships are defined as those involving a direct or indirect interest of any of our executive officers, directors, nominees for director and 5% stockholders, as well as specified members of the family or household of any of these individuals or stockholders, where we or any of our affiliates have participated in the transaction (either as a direct party or by arranging the transaction) and the transaction involves more than $120,000. In adopting this policy, our Board expressly excluded from its coverage any transactions, among others, involving compensation of our executive officers or directors that it or our Compensation Committee has expressly approved.

We have not engaged in any transactions with related persons since the beginning of our 20182020 fiscal year.

Compensation Committee Interlocks and Insider Participation

During 2018, the2020, our Compensation Committee members were Drs. Carter and Golumbeski, Ms. Peterson and Mr. Vance, none of whom currently is, or formerly was, an officer or employee of Enanta. None of our executive officers served as a member of the Boardboard of Directorsdirectors or Compensation Committeecompensation committee of any other company that had one or more executive officers serving as a member of our Board of Directors or Compensation Committee.

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EXECUTIVE OFFICERS

The following section provides biographical information as of December 1, 201815, 2020 about our current executive officers:

 

Name

Age

Name

   Age

Position

Jay R. Luly, Ph.D.

64

62

President and Chief Executive Officer

Yat Sun Or, Ph.D.

68

66

Senior Vice President, Research & Development and Chief Scientific Officer

Nathalie Adda, M.D.

55

53

Senior Vice President and Chief Medical Officer

Paul J. Mellett

65

63

Senior Vice President, Finance & Administration and Chief Financial Officer

Nathaniel S. Gardiner, J.D.

67

65

Senior Vice President and General Counsel

Timothy D. Ocain,Tara L. Kieffer, Ph.D.

43

61

Senior Vice President, New Product Strategy and Development

Jay R. Luly, Ph.D., has served as our President and Chief Executive Officer and as a member of our board of directors since July 2003. Prior to joining Enanta, Dr. Luly was an Entrepreneur in Residence at Oxford Bioscience Partners. Before joining Oxford in March 2002, Dr. Luly held the positions of Senior Vice President, Research and Development Operations and Senior Vice President, Discovery Strategy and Operations at Millennium Pharmaceuticals following Millennium’s merger with LeukoSite, Inc., where he had served as Senior Vice President, Drug Discovery and Preclinical Development. Prior to joining LeukoSite, he held a number of senior drug discovery positions at Abbott Laboratories from 1983 to 1997. Dr. Luly received a B.S. from the University of Illinois, Urbana/Champaign and a Ph.D. in synthetic organic chemistry from the University of California, Berkeley.

Yat Sun Or, Ph.D., has been our Senior Vice President, Research and Development and Chief Scientific Officer since November 1999. Prior to joining Enanta, Dr. Or held key leadership positions at Abbott Laboratories from 1985 to 1999, where he received two Chairman’s Awards for his outstanding research, which led to the discovery and development of immunosuppressant and antibacterial drugs. Prior to Abbott, Dr. Or was a member of the cardiovascular drug discovery team at Schering-Plough. Dr. Or received his Ph.D. in Organic Chemistry from the University of Chicago and completed Postdoctoral Fellowships at Ohio State University and Indiana University.

Nathalie Adda, M.D., has been our Senior Vice President and Chief Medical Officer since June 2015. Prior to joining Enanta, Dr. Adda was Chief Medical Officer, VP Clinical Development, Medical and Regulatory Affairs at Transgene SA, where she led the Oncology and Infectious Disease programs since 2012. From 2006 to 2012, she was Senior Medical Director and the medical lead for the Incivek® (telaprevir) Clinical Program at Vertex Pharmaceuticals, Inc. Earlier in her career, Dr. Adda held medical and research positions at Gilead, Triangle Pharmaceuticals and Boehringer Ingelheim, where she worked on programs for infectious diseases such as human immunodeficiency virus, hepatitis B virus and hepatitis C virus. Dr. Adda is a graduate of the University of Paris, where she received a Doctorate in Medicine, as well as a Master’s Degree in Biostatistics, and where she did post- graduate work in infectious diseases.

Paul J. Melletthas served as our Senior Vice President, Finance & Administration and Chief Financial Officer since September 2003. From April 2001 through August 2003, he held the position of Senior Vice President and Chief Financial Officer of Essential Therapeutics, Inc., a publicly-heldpublic biotechnology company. Previously, Mr. Mellett was the Chief Financial Officer and Vice President of Administration at GelTex Pharmaceuticals, Inc., a publicly held biotechnology company that was acquired by Genzyme Corporation in December 2000. From 1994 to 1997, Mr. Mellett served as Chief Financial Officer of Marshall Contractors, a construction management firm specializing in the pharmaceutical, biotechnology and semiconductor industries, which was acquired by Fluor Corporation in 1996. From 1977 to 1994, Mr. Mellett was employed with Deloitte & Touche LLP, a public accounting firm, and was promoted to Audit Partner in 1989. Mr. Mellett received a B.S. in Business Administration from Boston College in 1977.

College.

Nathaniel S. Gardiner, J.D.,has served as our Senior Vice President and General Counsel since May 2014 and has served as our Secretary since 1995. Previously Mr. Gardiner was a corporate and securities law partner for 25 years, most recently at Edwards Wildman Palmer LLP since October 2011, previously at Edwards Angell Palmer & Dodge LLP since November 2005, and before that at Palmer & Dodge LLP, where he represented Enanta and several other biotechnology companies. Mr. Gardiner received his A.B. from Harvard College and his J.D. from the University of Virginia School of Law.

Timothy D. Ocain,Tara L. Kieffer, Ph.D.has served, joined us as our Senior Vice President, New Product Strategy and Development since January 2014.in December 2020.  Previously Dr. Ocain had been a consultant to us since March 2012, while he was an independent biotechnology consultant providing consulting services to a variety of companies. From 2006 to 2009, Dr. Ocain was a member of the executive team and Senior Vice President, Research and Development at Seaside Therapeutics, a company focused on neurodevelopmental disorders. Previously, he worked at Millennium Pharmaceuticals from 1998 to 2006 andKieffer held positions of increasing responsibility in drug discovery, program management and mostlyat Vertex Pharmaceuticals Incorporated, a biotechnology company, most recently held the position ofas Vice President, Inflammation Discovery. BeforeExternal Innovation, Business Development since October 2018.  Prior to that he workedshe was Vice President, Integrated Program Management since March 2017, and Senior Director, Chief of Staff to the Chief Medical Officer from October 2014 to March 2017. In her previous ten years at Vertex she advanced as a virologist, becoming Director, Clinical Biomarkers in drug discoverythe Department of Translational Medical Sciences.  Dr. Kieffer did her graduate work at Procept, Inc.Johns Hopkins School of Medicine, Department of Molecular Biology and at Wyeth-Ayerst Research.Genetics from 1999 to 2004. Dr. OcainKieffer is a summa cum laude graduate of Colgate University and received his B.S. in Biological Sciences from the University ofWisconsin-Eau Claire and hisher Ph.D. in Pharmaceutical ChemistryImmunology from the UniversityJohns Hopkins School of Wisconsin-Madison, and completed his post-Doctoral Fellowship in Chemistry at the University of Minnesota.Medicine.

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EXECUTIVE COMPENSATIONCOMPENSATION

Compensation Discussion and Analysis

This section provides an overview and analysis of our executive compensation program, including its design and objectives, as well as the rationale applied and the decisions made under our program with respect to the compensation paid or awarded in fiscal 20182020 to Drs. Luly, Or and Adda and Messrs. Mellett and Gardiner, whom we refer to collectively as our Named Executive Officers, or NEOs. Later in this proxy statement, you will find a series of tables containing specific information about the compensation earned by these individuals in fiscal 2018.2020. The discussion below is intended to help you understand the detailed information provided in those tables and to put that information into context based on our overall compensation program for our Named Executive Officers.

Our Executive Compensation Philosophy

We rely on the expertise of our executive management team to drive overall company performance. Our compensation program is intended to align the interests of our Named Executive Officers with those of our stockholders by measuring and rewarding their performance against our research and development objectives. Consistent with thispay-for-performance philosophy, theour Compensation Committee has structured certain elements of the compensation program for our executive officers, including our NEOs, to reward performance by emphasizing equity compensation opportunities, as well as variable cash incentives that are based on corporate performance measured against annual objectives that arepre-established by theour Compensation Committee. In addition, a significant component of the executive equity compensation program is based on corporate performance against two-year research and development and business development objectives and relative total stockholder return.

TheOur Compensation Committee has determined that our executive compensation program will generally over time target the executive team’s base salaries, total target cash compensation and time-based equity awards to those of executives in the 50th percentile of comparable executives in our peer group companies over time.companies. In addition, theour Compensation Committee has expanded our executive team’s total equity compensation opportunity by including performance awards that target reaching approximately the equity compensation of the 75th percentile of comparable executives in our peer group companies if Enanta achieves high levels of performance against itsthe company’s longer-term objectives and the value of Enanta’s stock increases more relative to the traded stocks of other public biotechnology companies.

Our compensation philosophy is designed to promote our corporate objectives. Our guiding principles focus on:

Attracting, retaining and motivating top talent;

Aligning executive compensation with the attainment of our research and development objectives and business strategy;

Rewarding executives for achievement of near and long-term individual and corporate goals; and

Aligning executive compensation with long-term stockholder value and accomplishments that we believe will increase the increasing value of Enanta.Enanta in the long term.

Compensation Committee

Our board of directors has delegated authority to theour Compensation Committee, which currently consists of four of our sixnon-employee directors, to provide oversight of our executive compensation program for our NEOs as well as our other executive officers. TheOur Compensation Committee reviews and evaluates the executive compensation program on an annual basis to ensure that the program is aligned with our compensation philosophy. Since our compensation program is administered on a calendar year basis, theour Compensation Committee at its regularly scheduled November meeting reviews our corporate performance for the year and takes the following actions:

 

(i)

determines annual variable cash compensation;

 

(ii)

sets base salary and target percentages of base salary for variable cash compensation for the calendar year beginning January 1;

 

(iii)

grants stock option awards; and

 

(iv)

determines the number of shares that will be subject to performance unit awards.

TheOur Compensation Committee reviews these actions with the othernon-employee directors for their input before finalizing them. In addition, theour Compensation Committee makes recommendations to our Board of Directors, based on recommendations made by our compensation consultant, regardingnon-employee director fees and equity awards.

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Role of Compensation Consultant

Our Compensation Committee retains each year an independent compensation consulting firm to provide advisory services concerning our compensation programs for our executive officers andofficers. This consulting firm also reviews the fees and equity awards fornon-employee directors. directors on a biennial basis. These services include recommendations regarding our compensation practices and, based on direction from theour Compensation Committee, detailed analyses and recommendations based on the percentile rankings of comparable executives, as well asnon-employee directors, in our peer group companies.

Radford Consulting, an AON Consulting company, has been selected by our Compensation Committee for this role and has assisted the Compensation Committeecommittee by providing the following services in fiscal 2018:2020:

Competitive benchmarking and market data analysis, including data used for determining each of the components of the compensation of our CEO, Chief Scientific Officer, Chief Medical Officer, Chief Financial Officereach of our other NEOs, and other members of our executive management team;team, as well as for our non-employee directors;

Advice on industry compensation practices, including the structure and mix of equity compensation;

Review of equity plan materials provided by management to the Compensation Committee for discussion and approval; and

Participation in several of theour Compensation Committee’s meetings in fiscal 2018.2020.

In addition, the members of the Radford team provide advice to theour Compensation Committee and, other than providing data as mentioned below, the Radford team does not provide any other services. Management

works with Radford at the direction of the Committee to provide the consultant with all information it deems necessary to advise the Committee. Radford follows internal guidelines and practices to guard against any conflict of interest and to ensure the objectivity of its advice and has confirmed the same in writing to us.our Compensation Committee. After review and consultation with Radford, theour Compensation Committee has determined that Radford is independent of the company and the members of thethis committee.

Role of Company Management

Our CEO makes recommendations to theour Compensation Committee concerning our company performance relative to corporate performance objectives and proposed compensation of the other NEOs and any other executive officers. In addition, our CEO leads management in setting the research and development objectives that are used as the performance objectives for the variable cash compensation plan, subject to Compensation Committee review and approval, and he reviews any adjustments to our proposed peer group and provides suggestions to Radford for inclusions or exclusions. Our CEO works closely with theour Compensation Committee to ensure that theour Compensation Committee is provided with the appropriate information to make its decisions, including with respect to the performance of each of the other executive officerofficers relative to theireach officer’s individual annual performance objectives, and to propose recommendations for Compensation Committee consideration regarding the compensation elements of the otherfor those NEOs. Once our CEO has made his recommendations to theour Compensation Committee, this committee reviews them, including consultation with the othernon-employee directors regarding our CEO’s compensation, and makes the final compensation determinations. Once theour Compensation Committee evaluates compensation data from Radford and makes its final determinations for the other NEOs and other executive officers, those determinations are delivered to our CEO, who then communicates them to the management team.

Benchmarking and Use of Peer Group Data

Our executive compensation program seeks to provide total compensation at pay levels of executives with similar roles at comparable companies when targeted levels of performance are achieved. Use of survey data from our peers plays a significant role in the structure of the compensation program asbecause it is a primary input in setting target levels for base salaries, variable cash compensation and equity awards. These data also help to ensure that we provide compensation that is competitive with the market so that we can attract, retain and motivate talent.

As indicated above, theour Compensation Committee retains Radford to conduct a study of peer companies for the purpose of reviewing the compensation levels of our executive team, including the NEOs. Radford provides proposed changes, if any, to our peer group to theour Compensation Committee and theour Compensation Committee reviews the peer group and, based on the available data and input from members of the Committee, determines and approves the final peer group. TheOur Compensation Committee uses the peer group data to help identify a reasonable benchmark for base salaries, target variable cash compensation, time-based equity awards and target performance-based equity awards and then analyzes company and individual performance to determine whether it is appropriate to move away from this baseline. Peer group data also plays a role in determining thenon-cash compensation that is paid to the NEOs, as the market data we obtain regarding companies in our peer group informs what types and amounts ofnon-cash compensation are appropriate for competitive purposes.

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We believe that the design of our executive compensation program, with its emphasis on reward for achievement of the key objectives that comprise our annual and long-term business plan, does not create incentives for our executives to take excessive or unnecessary risks that could threaten the value of our company.

We also participate in compensation surveys conducted by Radford each year. The company has access to the resulting Radford reports, which are specific to the pharmaceutical and biotech industry and provide data on salaries, bonuses and equity grants for specific job functions. We use this information when reviewing the salaries and other compensation for all of our employees.

TheOur Compensation Committee retained Radford to conduct a competitive benchmarking analysis on executive compensation for compensation decisions to bethat were made at itsthis committee’s November 20172019 meeting. As an initial step

in that process, Radford reviewed the prior year’s criteria and, based on increaseschanges in our headcount and market capitalization, recommended changes to establishfor determining a peer group of companies that each met some or all of the following criteria, the first three of which were the primary criteria:

Public commercial biopharmaceutical companies with a product in Phase 2 or Phase 3 clinical development or on the market (preference for partnered orout-licensed products);market;

Market values generally between $260$400 million and $2.4 billion;$4 billion (preference for positive total stockholder returns);

 

High performingone- and three-year total stockholder returns;

Annual revenue of less thanbetween $50 million and $750 million;

Research and development expenditures between $60 million and $300 million; and

4050 to 350400 employees.

Radford reviewed the peer group approved by theour Compensation Committee in calendar 20162018 and determined that the profiles of a number of these companies did not meetwere well outside of the calendar 20172019 criteria. As a result, Merrimack Pharmaceuticals, NewLink Genetics, OncoMedAcorda Therapeutics, Adamas Pharmaceuticals and OpthotechAmarin were removed from the peer group, primarily due to the substantial increase intheir being outside of our market capitalization criteria, and HalozymeArray BioPharma and Keryx Biopharmaceuticals were removed due to acquisition or merger, respectively. Acceleron Pharma, Akebia Therapeutics, Esperion Therapeutics and Momenta PharmaceuticalsHeron Therapeutics were added to our peer group.

Based on the criteria set forth above, the final group of peer companies approved by theour Compensation Committee in calendar 20172019 was composed of the following companies:

 

Achillion Pharmaceuticals

Array BioPharma

Curis

ImmunoGen

Ligand Pharmaceuticals

PTC Therapeutics

Supernus Pharmaceuticals

Adamas Pharmaceuticals

Celdex Therapeutics

Cytokinetics

Karyopharm Therapeutics

Momenta Pharmaceuticals

Rigel Pharmaceuticals

Theravance Biopharma

AmarinAcceleron Pharma

Corcept Therapeutics

Halozyme Therapeutics

Keryx BiopharmaceuticalsIntercept Pharmaceuticals

MacroGenics

Omeros

SucampoSupernus Pharmaceuticals

Akebia Therapeutics

Esperion Therapeutics

Heron Therapeutics

Karyopharm Therapeutics

Mirati Therapeutics

PTC Therapeutics

Theravance Biopharma

Arena Pharmaceuticals

FibroGen

ImmunoGen

Ligand Pharmaceuticals

Momenta Pharmaceuticals

Sangamo Therapeutics

Vanda Pharmaceuticals

TheFor purposes of year-end calendar 2020 compensation analysis and determinations, which occurred after the fiscal 2020 data presented in this proxy statement, our Compensation Committee, with the assistance of Radford, made several changes to the peer group in September 2018 for purposes ofyear-end calendar 2018 compensation analysis and determinations.2020. At that time, the criteria were adjusted to increase the range of market values to be generally between $600 millionfocus on companies with lead products in Phase 2 or Phase 3 clinical development and $5.4 billion,change the range of annual revenues to $75$50 million to $675$500 million, and the range of employees to 50 to 450,under 600, and to add a criteriumthe range of research and development expense in the range ofto $40 million to $250 million. Based on the revised criteria, theOur Compensation Committee removed from the peer group AchillionAcceleron based on its increased market capitalization, and Momenta Pharmaceuticals Celldex Therapeutics, Curis, Cytokinetics and Rigel Pharmaceuticals, primarily due to changesits acquisition. Based on the revised criteria, our Compensation Committee added Assembly Biosciences, Dicerna Pharmaceuticals and Poseida Therapeutics.

Advisory “Say on Pay” Vote

At our 2020 Annual Meeting of Stockholders, approximately 93% of the shares voted on our annual “say-on-pay” proposal were cast in favor of the updated market capitalization criteriacompensation of our named executive officers as disclosed in our 2020 proxy statement. The Compensation Committee considered the results of the 2020 shareholder advisory vote on executive compensation when determining the Company’s 2021 executive and NEO compensation, and will continue to consider the results of shareholder advisory votes on executive compensation when making future decisions relating to our executive compensation programs and compensation for our peer group, as well as Sucampo, which was acquired, and added Acorda Therapeutics, Arena Pharmaceuticals, FribroGen, Intercept Pharmaceuticals, MacroGenics, Mirati Therapeutics and Sangamo Therapeutics.NEOs.

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Executive Compensation Elements

The main components of our executive compensation program are:

Base salary;

Annual variable cash compensation;

Long-term equity incentives awards consisting of:

stock options and restricted stock units with time-based vesting; and

restricted stock units with two types of performance-based vesting; and

Benefits, including 401(k) safe harbor match and medical benefits.

The following discussion describes how each of these elements of compensation fit into our overall compensation objectives and describes how and why compensation decisions were made by our Compensation Committee with respect to each element based on our compensation consultant’s analysis of competitive market data and our annual review of corporate and individual performance.

Base Salaries

Base salaries are paid in order to provide a fixed component of compensation for our NEOs and other executive officers to reward the individual value that each NEO brings to us through experience and past and expected future contributions to our success. At theour Compensation Committee meeting on November 16, 2017,15, 2019, the Committee established the base salaries of the NEOs for calendar year 20182020 to be within a range that is competitive with salaries paid to executives in the 50th percentile among comparable executives at companies in our peer group. TheOur Compensation Committee increased the base salary of each of our NEOs for calendar year 20182020 from 20172019 levels primarily based on the applicable peer group data for comparable executives.

Annual Variable Cash Compensation

Our variable cash compensation program is intended to reward corporate performance and individual performance by providing our executive officers with an opportunity to receive additional cash compensation. Our CEO’s variable cash compensation whichis determined solely based on the company’s performance relative to the corporate objectives for the year. In the case of the other executive officers, variable cash compensation is based on both the company’s performance relative to the corporate objectives and theour Compensation Committee’s assessment of how well the executive officer performed against his or her individual objectives during the applicable year.year, based substantially on the assessment of individual performance presented by our CEO. The CEO’starget variable cash compensation is determined solely based on the company’s performance relativethen subject to corporate objectives.an overall limit of 150% of each NEO’s target amount.

Target Setting. Variable cash compensation targets, which are set as a percentage of base salary for all NEOs and other executive officers, were set within a range that is competitive with annual variable cash compensation paid to executives in the 50th percentile among comparable executives at companies in our peer group. TheOur Compensation Committee has the discretion to adjust each NEO’s target as it deems appropriate. Potential reasons for adjusting targets for variable cash bonus targetscompensation include considerations of pay equity within Enanta and how the officer’s base salary, upon which the bonusvariable cash compensation is based, has increased historically.

Elements of Variable Cash Compensation. For all executive officers other than the CEO, target variable cash compensation is determined based on two components: corporate performance and individual performance with 70% of variable cash compensation based on corporate performance and 30% on individual performance. The target percentages and the relative weighting of objectives for the NEOs for the variable cash compensation paid at the end of calendar 20172020 were as follows:

 

Target % for

 

 

Relative Weighting

 

  Target % for
Variable Cash
  

 

 

Variable Cash

 

 

Corporate

 

 

Individual

 

NEO

 Corporate Individual 

Jay R. Luly, Ph.D

   60 100 0

Yat Sun Or, Ph.D

   40 30 70

Jay R. Luly, Ph.D.

65%

 

 

100%

 

 

0%

 

Yat Sun Or, Ph.D.

40%

 

 

70%

 

 

30%

 

Nathalie Adda, M.D.

   40 30 70

40%

 

 

70%

 

 

30%

 

Paul J. Mellett

   40 30 70

40%

 

 

70%

 

 

30%

 

Nathaniel S. Gardiner, J.D.

   40 30 70

40%

 

 

70%

 

 

30%

 

For variable cash compensation in calendar 2018, the Compensation Committee adjusted the weighting of the elements for NEOs other than our CEO so that corporate performance would be 70% of variable cash compensation and individual performance would be 30%.26


Corporate Performance Objectives. Near the beginning of each calendar year, theour Compensation Committee, after considering the recommendations of management and our overall strategic goals, confirms our corporate objectives for the year and the proportional emphasis placed on each broad category of objectives. These objectives generally relate to categories that our Compensation Committee determines can add the most value to Enanta, such as research and

development objectives, which constitute a substantial majority of the weighting of the objectives, and other factors primarily within management’s control. Because they are outside of management’s control, the level of sales achieved for our products licensed to AbbVie isare outside of management’s control, those sales are not a factor considered in determining annual variable compensation. OurAt the end of the year our Compensation Committee determines the level of achievement of the corporate objectives for eachthe year. This achievement level is then applied to the portion of each NEO’s target bonusvariable compensation determined by corporate performance for that year.

Our annual corporate performance is measured against ourdetermined based on achievement of one or more of the key research and development objectives for the year. Accordingly, at the beginning ofFor calendar 2017,year 2019, our CEO proposed objectives primarily focused on the advancement of our research programs, our clinical programs and external opportunities to augment our research and development pipeline in RSV, NASH/PBC and HBV. Thepipeline. Our Compensation Committee then reviewed and revised these objectives and determined their weighting.relative weighting for each category of objectives and the maximum payout for corporate performance, which was 150% of each NEO’s target variable cash compensation. Our Compensation Committee then reviewed and revised these objectives, using a relative weighting for each category of objectives similar to the weighting in calendar 2018, with the same maximum payout of 150% for corporate performance. In November 2017 the2019 our Compensation Committee reviewed our performance against these objectives and determined a corporate performance rating based on objectives related to the following:

InitiationCompletion of aproof-of-concept clinicalthe RSV challenge study with EDP-938 and initiation ofEDP-305 in primary biliary cholangitis patients; the RSVP study;

Initiation of a Phasephase 1 clinical study ofEDP-938 in healthy volunteers; EDP-514;

Completion of toxicology and manufacturing activities necessary to advanceEDP-305 into Phasethe ARGON-1 study;

Completion of sufficient enrollment in the phase 2 study of EDP-305 in PBC patients;

Preclinical development of EDP-297 as a follow-on FXR agonist candidate for clinical studies;development;

IdentificationAdvancement ofback-up compounds for our clinical compounds and research objectives related toin new mechanisms of action in the relatedour core disease areas; and

Activities related to external opportunities to augment our research and development pipeline;pipeline.

For calendar year 2020, our CEO proposed objectives primarily focused on the advancement of our research programs, our clinical programs and external opportunities to augment our research and development pipeline, using a relative weighting for each category of objectives with a maximum payout of 150% for corporate performance. Our Compensation Committee then reviewed and approved these objectives in December 2019. In November 2020 our Compensation Committee reviewed our performance against these objectives and, in the context of the COVID-19 pandemic, which had suspended some of our clinical studies and interrupted our laboratory research, particularly during the lock-downs after March 2020, determined a corporate performance rating based on objectives related to the following:

Completion of preclinical development to nominate EDP-721 as an HBV RNA destabilizer candidate for clinical development;

Initiation of a phase 2 study of EDP-938 in elderly RSV patients;

Completion of preclinical development and advancement for a phase 2 study of EDP-938 in pediatric patients;

Initiation of two phase 1b studies of EDP-514, one in so-called nuc-suppressed HBV patients and the other in viremic patients not on any other therapy;

Initiation and advancement of the ARGON-2 study of EDP-305 in NASH patients;

Preparation for and initiation of a phase 1 study of EDP-297; and

Activities related to increasingAdvancement of research in new mechanisms of action in our profile in the investment community.core disease areas.

TheOur Compensation Committee which has full discretion to determine corporate performance against our annual corporate objectives,objectives. In calendar 2019, our Compensation Committee determined that we had achieved, or would achieve, substantially allsufficient results against the calendar 20172019 performance objectives to award a corporate performance rating of 90%. After reviewing our CEO’s recommendations with respect to the individual performance of the NEOs other than our CEO, our Compensation Committee also determined that our Chief Scientific Officer and awardedour Chief Medical Officer achieved 90% and 115%, respectively, of their individual objectives, several of which were specific research and

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clinical development objectives closely tied to the company’s ability to achieve the corporate objectives described above, and that our Chief Financial Officer and our General Counsel each achieved 100% of their individual objectives related to the performance of their respective groups and their individual responsibilities.

In calendar 2020, our Compensation Committee determined that we had achieved, or would achieve, sufficient results against the calendar 2020 performance objectives, particularly in light of the challenges of managing operations during the COVID-19 pandemic, to award a corporate performance rating of 100%. After reviewing our CEO’s recommendations with respect to the individual performance of the NEOs other than our CEO, theour Compensation Committee also determined that our Chief Scientific Officer and our Chief Medical Officer achieved 108%100% and 105%85%, respectively, of their respective individual objectives, several of which were specific research and clinical development objectives closely tied to the company’s ability to achieve the corporate objectives described above, and that our Chief Financial Officer and our General Counsel each achieved 100% of their individual objectives related to the performance of their respective groups and their individual responsibilities.

The “Summary Compensation Table” following this discussion includes information, under the column“Non-Equity “Non-Equity Incentive Plan Compensation”, concerningthat is a prorated blend of the actual variable cash compensation paid toearned by each NEO duringin calendar 2020 and 2019 (i.e., the proration in fiscal year ended September 30, 2018.2020 was 25% of variable cash compensation for performance in the calendar year ending December 31, 2019 and 75% of variable cash compensation for the calendar year ending December 31, 2020).

Long-term Equity Incentive Awards

Equity awards have the potential to be a significant component of each NEO’s compensation package. We emphasize equity awards to motivate our NEOs to drive the long-term performance of Enanta and to align their interests with those of our stockholders. We believe this emphasis is appropriate as these officers have the greatest role in establishing Enanta’s direction and should have a significant proportion of their compensation aligned with the long-term interests of stockholders. TheOur Compensation Committee has established two types of equity awards, each of which now has two components, to serve as these long-term incentives.

Stock OptionsEquity Awards with Time-Based Vesting.TheOur Compensation Committee makeshas traditionally made annual grantsawards of stock options to provide a certain amount of equity to officers that will vest as long as the officer continues to work at Enanta. These grants align the interests of our NEOs with those of our stockholders because the grants will only have value as long asif the market value of our common stock increases from the date of grant. To encourage

retention and focus our executives on building long-term value for our stockholders, we typically structure our annual stock option awards so that they vest over a service period of four years. The size of stock option awards for our NEOs is then set within a range that is competitive with equity awards granted to comparable officers at companies in our peer group. The number of shares subject to each NEO stock option is based primarily on Radford’s determination of the Black-Scholes value of equity awards granted to executives in the 50th percentile of executives in comparable roles in our peer group companies, and then using that value to determine a number of shares of our common stock based on our Black-Scholes formula used to value our stock options in our financial statements. TheOur Compensation Committee makes final adjustments to the specific number of shares after receiving recommendations from our CEO.

On November 17, 2017, the16, 2019, our Compensation Committee granted to each of our NEOs awards ofnon-statutory stock options vesting over four years in equal quarterly installments with respect to a designated number of shares as follows: Dr. Luly, 100,000110,000 shares; each of Drs. Or and Adda 23,500 shares; Mr.and Messrs. Mellett 22,500 shares; and Mr. Gardiner, 21,500Gardiner: 30,000 shares.

In the compensation review process in each of calendar 2018 and 2019 our Compensation Committee considered, based on data presented by Radford, whether any portion of the annual stock option awards should be replaced with awards of restricted stock units, or RSUs, with comparable time-based vesting. In November 2020, based primarily on a determination to provide a portion of annual awards as full value awards that would not lose substantially all perceived value in a downturn of the price of our common stock, our Compensation Committee decided to replace one third of the target value of what would otherwise have been stock option awards with an award of restricted stock units that will vest annually over four years. The number of full-value RSU awards is based on the Black-Scholes value of the target number of stock options that the RSUs are replacing, using the same formula inputs as are used to value our stock options in our financial statements.

Restricted Stock Units with Performance-Based Vesting.To provide additional incentive for longer-term performance that can allow our executive officers to achieve levels of equity awards at or above the 75th percentile of executives in comparable roles in our peer group companies, theour Compensation Committee also makes annual awards of performance share units, or PSUs, and relative total stockholder return units, or rTSRUs, to each of our executive officers. Half of these units are designed to vest based on high levels of performance against specific research and development andnon-financial business objectives of Enanta over atwo-year period. The other half are designed to vest based on

28


if there is a high relative total stockholder returns ofreturn on our common stock versus the stocks of the other companies in the NASDAQ Biotech Index when comparing a two-month period at base-line to the comparable period two years later.

Our Compensation Committee has determined that a 2-year performance period is appropriate because, unlike more mature companies that have performance units vesting based on improving financial performance with numerically precise criteria, value in Enanta (whether directly measured by our stock price or events that affect that price) is created based on advances in our research and development programs, none of which has advanced yet beyond phase 2. In addition, the performance criteria need to be precisely and rigorously defined. General experience in research and development in biotechnology has demonstrated that over a26-month period of two years these types of early stage programs rarely progress exactly as planned, primarily due to matters outside of management’s control, such as failures in preclinical testing or unexpected side-effects or lack of efficacy in early stage human studies. As a result, trying to set objective targets more than two years ahead would likely fail to provide any effective incentive during the full performance period since the chances would significantly increase that the objective would become unattainable well before the end of the performance period.

To initially bracket the target number of units, Radford determines the difference in the dollar values of the annual equity awards for executives in the 50th percentile and the 75th percentile of comparable executives in our peer group companies, and then converts that differential value into a number of full value shares of our common stock based on our Black-Scholes formula used to value our stock options in our financial statements. Based on that number of shares, theour Compensation Committee then determines a target number of total units for each NEO, based in part on considerations of pay equity and the relative roles of the NEOs. The resulting target number of units is then split evenly between PSUs and rTSRUs for each NEO. These unit awards typically have a performance period of two years, ending on December 31 of the second year, and then after theyear. After our Compensation Committee determines the level of performance achieved, and provided that the NEO is still employed at Enanta, the underlying shares settle and are issued to the NEO in the following February.

In the case of the PSUs awarded in fiscal 2018,2020, unit vesting will be based on achievement of research and development milestones in each of three categories of activities: (i) advancement of clinical programs; (ii) advancement of research programs; and (iii) other value-driving opportunities generally involving assets outside of our research and development programs. These milestones, which relate to our key programs, are weighted based on theour Compensation Committee’s assessment of the relative value of the milestones. Each program’s milestone is considered to be challenging to achieve, meaning that the likelihood of success during the performance period is possible, but not high, becausehigh. This also means that the chances that multiple milestones are achieved is even lower than for any single milestone. In the case of program milestones, every development activity for the particular program will have to progress substantially as and when planned in order to achieve thetwo-year objective for that program. General experience in research and development in biotechnology has demonstrated that over a period of two years these types of earlyEarly stage programs rarely progress exactly as planned, primarily because delays due to matters outside of Enanta are common.often experience delays. In addition, to project delays, the failure rate is quite high for compounds in the early stages of discovery and preclinical and early clinical development. In the case of milestones for assets outside of Enanta, achievement will require success in identifying an available asset, validating the potential of the asset and its value to Enanta, and negotiating and completing a transaction on terms acceptable to all parties, much of which is outside of Enanta’s control. For these reasons we call the PSU milestones “stretch goals” because they are hard to reach, i.e. achieve.

On March 1, 2018, theDecember 20, 2019, our Compensation Committee awarded our executive officers PSUs with milestones in each of the three categories:

•       Clinical milestones:

Specific clinical milestones for each of EDP-938 (RSV), EDP-305 (NASH/PBC) (NASH), EDP-514 (HBV) andEDP-938 (RSV) EDP-297 (NASH), as well as the possibility ofin-licensing and advancement of an external compound.

•       Research milestones:

Specific research milestones for HBV and for additional RSV and liver disease compounds, as well as advancement of any new mechanism of action or candidates for a new disease area.

•       Other value-driving milestones:

In-licensing and advancement of a novel compound or identification and advancement of a combination therapy.therapy into a clinical study.

Achievement of one of the clinical milestones will vest 70% of each NEO’s target number of PSU shares and achievement of a second clinical milestone will vest an additional 50% (reflecting a vesting of 120% of the target number of PSU shares), achievement of one research or other value driving milestone will each vest 15% of the target number of PSUs, but achievement of additional milestones in those two categories will not vest any additional shares. If one milestone in each of the three categories is achieved by December 31, 2019,2021, then each NEO’s target number of PSU shares will vest, and if an additional clinical milestone is achieved, then 150% of each NEO’s target number of PSU shares will vest. The maximum payout for PSUs awarded in fiscal 20182020 is capped at 150% of each NEO’s target number of PSU shares.

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In the case of the rTSRUs awarded on March 1, 2018,December 20, 2019, these awards will vest and result in the issuance of shares of our common stock based upon the relative ranking of the total stockholder return, or TSR, of Enanta’s common stock in relation to the TSR of the component companies in the NASDAQ Biotech Index using a comparison of average closing stock prices over the60-day period ended December 31, 20172019 compared to the60-day period ending December 31, 2019.2021. The rTSRUs are intended to reward increases in the relative market value of our common stock that might not relate directly to specific long-term objectives of internal research and development efforts reflected in the PSUs but that nonetheless are reflected in our market value and our returns for our stockholders. The number of market-based rTSRUs awarded represents the target number of shares of common stock that may be earned; provided, however, that the actual number of shares that may be earned ranges from 0% to 150% (0% to 200% for rTSRUs awarded before 2018) of the target number, depending on Enanta’s ranking in that index. No rTSRU shares will vest if there is no increase in the value of Enanta’s stock during the period, nor will any rTSRU shares vest if Enanta’s stock is ranked below the 65th percentile. The rTSRUs will vest as to 50%, 100% or 150% of the target number of rTSRU shares if the stock is ranked at the 65th, the 75th or at or above the 85th percentiles, respectively. If our ranking falls between the 65th and 85th percentiles, there will be interpolation between the fixed vesting amounts of the 65th, 75th and 85th percentiles based on the relative ranking of our stock.

Benefits

Health and Welfare Benefits.Our NEOs are eligible to participate in all of our employee benefit plans, including our medical, dental, vision, group life and disability insurance plans, in each case on the same basis as other employees. We believe that these health and welfare benefits help ensure that we have a productive and focused workforce through reliable and competitive health and other benefits.

Retirement Savings.All of our full-time employees, including our NEOs, are eligible to participate in our 401(k) plan. Pursuant to our 401(k) plan, employees may elect to reduce their current compensation by up to the statutorily prescribed annual limit (which was $18,500$19,000 in calendar 2018)2019), with additional salary deferrals not to exceed $6,000 available to those employees 50 years of age or older, and to have the amount of this reduction

contributed to our 401(k) plan. In addition, in 2018fiscal 2020, 2019 and 20172018 we made matchingcompany contributions in the amount of 6% of base salary, up to a maximum of $16,800, $16,500 and $16,200, and $15,900, respectively, per year. In 2016, we made matching contributions in the amount of 5% of base salary, up to a maximum of $13,250 per year. This was based on our policy of making profit-sharing contribution to each employee’s account in amounts ranging from 3% to 6% of base salary and bonus compensation paid in the calendar year, regardless of whether the employee makes a contribution to the 401(k) plan in that year. The percentage of the profit sharingprofit-sharing contribution above 3% is based on Enanta’s performance for the year. The 401(k) Plan currently does not offer the ability to invest in our securities.

Perquisites. We do not provide significant perquisites or personal benefits to our NEOs. We do, however, pay the premiums for term life insurance for NEOs.

Severance and Change of Control Benefits

Pursuant to employment agreements, our NEOs are entitled to specified benefits in the event of the termination of their employment under specified circumstances, including termination without cause or for good reason.

We believe that severance protections, particularly in the context of a change of control transaction, can play a valuable role in attracting and retaining executive officers, are an important part of an executive’s total compensation package and are consistent with competitive practices. We believe that the occurrence, or potential occurrence, of a change of control will create uncertainty regarding the continued employment of our NEOs. This uncertainty results from the fact that many change of control transactions result in significant organizational changes, particularly at the senior executive level. Our practice, in the case of our employment agreements, has been to structure these change of control benefits as “double trigger” benefits. In other words, the change of control does not itself trigger benefits; rather, benefits are paid only if the employment of the NEO is terminated during the12-month (or18-months in the case of the CEO) period after the change of control. We believe a “double trigger” benefit maximizes stockholder value because it prevents an unintended windfall to executives in the event of a friendly change of control, while still providing them appropriate protections as incentives to cooperate in negotiating any change of control in which their jobs may be at risk. Because we believe that a termination by the executive for good reason is conceptually the same as a termination by us without cause, and that in the context of a change of control potential acquirers would otherwise have an incentive to constructively terminate the executive’s employment to avoid paying severance, we provide severance benefits in these circumstances. We have provided more detailed information about these benefits, along with estimates of their value under various circumstances, under the caption“— Potential Payments Upon Termination, Including Termination After a Change in Control Transaction” below.

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Corporate Policies Covering Executive Compensation

Policy Against Hedging

As part of our insider trading policy, all employees, including executive officers, and members of our Board of Directors are prohibited from engaging in hedging transactions involving our securities, including short sales, including short sales “against the box,” and purchases or sales of puts, calls or other derivative securities. Our insider trading policy also prohibits pledges of our securities by all employees, including executive officers, and members of our Board of Directors, including purchases of our securities on margin, borrowing against our securities held in a margin account or pledging our securities as collateral for a loan, with an exception for a pledge of our securities as collateral for a loan only after clearly demonstrating the financial capacity to repay the loan without resort to the pledged securities and then only with the pre-approval of our Chief Financial Officer. To date, no such pledge of our securities has been approved.

Policy Against Repricing Stock Options

We have a consistent policy against the repricing of stock options without stockholder approval.

Equity Incentive Awards - Mechanics and Timing

TheOur Compensation Committee approves all equity awards to NEOs, including the CEO.

For annual option awards, the grant date is the date during November when theour Compensation Committee and the full Board of Directors meet. TheOur Compensation Committee’s procedure for timing of stock option awards assures that grant timing is not being manipulated for employee gain. This grant date timing coincides with Enanta’s calendar-year-based employee review cycle, allowing managers to deliver the equity awards close in time to performance appraisals, which increases the impact of the awards by strengthening the link between pay and performance.

The exercise price for all awardsstock options to the NEOs (including the CEO) is the fair market value of our common stock on the date of the grant, which we schedule to be the same date that all our employees receive their annual equity awards. The fair market value of our common stock as of theany particular date is defined by theour Compensation Committee as the closing price of our common stock on the date of the grant.

that date.

TheOur Compensation Committee does not grant equity awards in anticipation of the release of material nonpublic information. Similarly, we do not time the release of material nonpublic information about the company based on equity award grant dates.

Policy Against Hedging

As part of our insider trading policy, all employees, including executive officers, and members of our board of directors are prohibited from engaging in certain types of hedging transactions involving our securities, specifically short sales, including short sales “against the box,” and purchases or sales of puts, calls or other derivative securities. Our insider trading policy also prohibits certain types of pledges of our securities by all employees, including executive officers, and members of our board of directors, specifically purchases of our securities on margin, borrowing against our securities held in a margin account or pledging our securities as collateral for a loan, with an exception for pledges of our securities as collateral for a loan only after certain prerequisites are met and only with thepre-approval of our Chief Financial Officer.

Policy Against Repricing Stock Options

We have a consistent policy against the repricing of stock options without stockholder approval. In addition, if approved by our stockholders at this meeting, our 2019 Equity Plan will prohibit any action that is considered a direct or indirect “repricing” of stock options unless we obtain stockholder approval.

Federal Tax Considerations under Section 162(m)

Section 162(m) of the Internal Revenue Code of 1986, as amended, or the Code, generally disallows a tax deduction to public companies for compensation in excess of $1 million paid to each of a company’s chief executive officer, chief financial officer and the three most highly compensated executive officers (other than the chief executive officer and chief financial officer). Pursuant to the Tax Cuts and Jobs Act of 2017, or the Tax Act, for taxable years beginning after December 31, 2017, the Section 162(m) deduction limitation is expanded so that it also applies to compensation in excess of $1 million paid to a public company’s chief financial officer. Historically, compensation that qualified under Section 162(m) as performance-based compensation was exempt from the deduction limitation. However, subject to certain transition rules, the Tax Act eliminated the qualified performance-based compensation exception. As a result, for taxable years beginning after December 31, 2017, allAll compensation in excess of $1 million paid to each of the executives described above (other than certain grandfathered compensation in effect before November 2017) will not be deductible by us.

While theour Compensation Committee considers the deductibility of awards as one factor in determining executive compensation, theour Compensation Committee may also look at other factors in making its decisions and retains the flexibility to award compensation that it determines to be consistent with the goals of our executive compensation program even if the compensation is not deductible by us for tax purposes.

COMPENSATION COMMITTEE REPORT

TheThis Compensation Committee has reviewed the Compensation Discussion and Analysis and discussed that analysis with management. Based on its review and its discussions with management, thethis Compensation Committee recommended to our Board of Directors that the Compensation Discussion and Analysis be included in this proxy statement.

By the Compensation Committee,

Kristine Peterson, Chair

George S. Golumbeski, Ph.D., Chair

Bruce L.A. Carter, Ph.D.

Kristine Peterson

Terry C. Vance

January 17, 2019

21, 2021

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Summary CompensationCompensation Table

The following table sets forth information regarding compensation paid to our NEOs:

 

Name and Principal Position

 Year  Salary
($)(1)
  Bonus
($)(2)
  Stock
Awards
($)(3)
  Option
Awards
($)(4)
  Non-Equity
Incentive Plan
Compensation
($)(5)
  All Other
Compensation
($)(6)
  Total ($) 

Jay R. Luly, Ph.D.

  2018   611,178   —     838,530   2,684,490   355,688   18,851   4,508,737 
President and Chief Executive Officer  2017   581,203   —     1,279,980   2,055,720   314,163   18,551   4,249,617 
  2016   542,393   —     404,953   2,182,686   291,751   15,857   3,437,640 

Yat Sun Or, Ph.D.

  2018   427,950   —     275,275   630,855   171,072   18,851   1,524,003 
Senior Vice President, Research & Development and Chief Scientific Officer  2017   400,975   —     574,369   599,585   166,605   18,551   1,760,085 
  2016   386,069   —     122,428   654,806   151,030   15,857   1,330,190 
        

Nathalie Adda, M.D.

  2018   421,425   —     275,275   630,855   167,670   18,851   1,514,076 
Senior Vice President, Chief Medical Officer  2017   400,313   —     574,369   599,585   159,521   18,551   1,752,339 
  2016   383,438   52,500   162,081   317,482   65,625   15,857   996,983 

Paul J. Mellett

  2018   394,937   —     254,100   604,010   149,379   18,851   1,421,277 
Senior Vice President, Finance & Administration and Chief Financial Officer  2017   370,728   —     557,078   513,930   142,127   18,551   1,602,414 
  2016   359,930   —     108,301   595,278   123,204   15,857   1,202,570 
        

Nathaniel S. Gardiner, J.D.

  2018   398,850   —     232,925   577,165   148,320   18,851   1,376,111 
Senior Vice President and General Counsel  2017   368,100   —     545,550   428,275   151,200   18,551   1,511,676 
  2016   353,403   —     94,175   505,986   116,764   15,857   1,086,185 

Name and Principal Position

 

Year

 

Salary ($)(1)

 

 

Bonus ($)

 

 

Stock Awards ($) (2)

 

 

Option Awards ($) (3)

 

 

Non-Equity Incentive Plan Compensation ($) (4)

 

 

All Other Compensation  ($) (5)

 

 

Total ($)

 

Jay R. Luly, Ph.D.

 

2020

 

 

667,063

 

 

 

 

 

 

497,039

 

 

 

3,598,848

 

 

 

415,716

 

 

 

19,171

 

 

 

5,197,837

 

President and Chief Executive Officer

 

2019

 

 

641,825

 

 

 

 

 

 

457,603

 

 

 

3,027,598

 

 

 

337,326

 

 

 

19,151

 

 

 

4,483,503

 

 

 

2018

 

 

611,178

 

 

 

 

 

 

838,530

 

 

 

2,684,490

 

 

 

311,150

 

 

 

18,851

 

 

 

4,464,199

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Yat Sun Or, Ph.D.

 

2020

 

 

472,075

 

 

 

 

 

 

187,821

 

 

 

981,504

 

 

 

184,230

 

 

 

19,171

 

 

 

1,844,801

 

Senior Vice President, Research & Development

 

2019

 

 

427,950

 

 

 

 

 

 

275,275

 

 

 

630,855

 

 

 

159,074

 

 

 

18,851

 

 

 

1,512,005

 

and Chief Scientific Officer

 

2018

 

 

400,975

 

 

 

 

 

 

574,369

 

 

 

599,585

 

 

 

169,955

 

 

 

18,551

 

 

 

1,763,435

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Nathalie Adda, M.D.

 

2020

 

 

451,550

 

 

 

 

 

 

187,821

 

 

 

981,504

 

 

 

173,372

 

 

 

19,171

 

 

 

1,813,418

 

Senior Vice President, Chief Medical Officer

 

2019

 

 

421,425

 

 

 

 

 

 

275,275

 

 

 

630,855

 

 

 

148,216

 

 

 

18,851

 

 

 

1,494,622

 

 

 

2018

 

 

400,313

 

 

 

 

 

 

574,369

 

 

 

599,585

 

 

 

165,633

 

 

 

18,551

 

 

 

1,758,451

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Paul J. Mellett

 

2020

 

 

425,894

 

 

 

 

 

 

187,821

 

 

 

981,504

 

 

 

167,453

 

 

 

19,171

 

 

 

1,781,843

 

Senior Vice President, Finance & Administration

 

2019

 

 

394,937

 

 

 

 

 

 

254,100

 

 

 

604,010

 

 

 

141,087

 

 

 

18,851

 

 

 

1,412,985

 

and Chief Financial Officer

 

2018

 

 

370,728

 

 

 

 

 

 

557,078

 

 

 

513,930

 

 

 

147,566

 

 

 

18,551

 

 

 

1,607,853

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Nathaniel S. Gardiner, J.D.

 

2020

 

 

431,025

 

 

 

 

 

 

187,821

 

 

 

981,504

 

 

 

169,470

 

 

 

19,171

 

 

 

1,788,991

 

Senior Vice President and General Counsel

 

2019

 

 

398,850

 

 

 

 

 

 

232,925

 

 

 

577,165

 

 

 

142,396

 

 

 

18,851

 

 

 

1,370,187

 

 

 

2018

 

 

368,100

 

 

 

 

 

 

545,550

 

 

 

428,275

 

 

 

149,040

 

 

 

18,551

 

 

 

1,509,516

 

1)

The amounts shown in the “Salary” column represent the total base salary earned during the designated fiscal year. Annual cash compensation is determined by theour Compensation Committee and is adjusted on a calendar year basis, effective at the beginning of the calendar year. The following were the base salaries approved by theour Compensation Committee for each calendar year:

 

Calendar Year

 

 

2020

 

 

2019

 

 

2018

 

Jay R. Luly, Ph.D.

$

672,750

 

 

$

650,000

 

 

$

617,300

 

Yat Sun Or, Ph.D.

$

476,100

 

 

$

460,000

 

 

$

435,600

 

Nathalie Adda, M.D.

$

455,400

 

 

$

440,000

 

 

$

426,900

 

Paul J. Mellett

$

429,525

 

 

$

415,000

 

 

$

402,100

 

Nathaniel S. Gardiner, J.D.

$

434,700

 

 

$

420,000

 

 

$

408,200

 

 

   Calendar Year 
   2018   2017   2016 

Jay R. Luly, Ph.D.

  $617,300   $592,813   $546,371 

Yat Sun Or, Ph.D.

  $435,600   $405,000   $388,901 

Nathalie Adda, M.D.

  $426,900   $405,000   $386,250 

Paul J. Mellett

  $402,100   $373,447   $362,570 

Nathaniel S. Gardiner, J.D.

  $408,200   $370,800   $360,000 

2)

The amounts“Stock Awards” column includes awards made in the first quarter of the fiscal year, e.g. awards in November 2019 are shown in the “Bonus” column representssign-on bonuses paid to the named executive officer.

3)

year 2020. The amounts in the “Stock Awards” column reflect the grant date fair value of the relative total stockholder return units, or rTSRUs, and any time-based restricted stock units, or RSUs, awarded during the respective fiscal year in accordance with Accounting Standards Codification (“ASC”) 718. The grant date fair value of the RSUs, which were only awarded in fiscal 2017, was determined based on the closing price of the Company’s common stock on the date of grant, November 18, 2016. The grant date fair value of the rTSRUs wasis determined based on a Monte Carlo simulation model as of the grant date. Monte Carlo assumptions used in this calculation are included beginning on pageF-24 F-20 in Footnote 10 of our Annual Report onForm 10-K for the year ended September 30, 2018,2020, referred to herein as our 20182020 Form10-K. In each case, the rTSRUs that are granted annually measure relative stockholder return during a period at the end of the calendar year in which the number of rTSRUs is determined compared to the same calendar period two years later, regardless of when the grant date of the rTSRUs occurs.

A total of 90% of the target amounts of rTSRUs granted in March 2018 vested at December 31, 2019 because our total stockholder return relative to the other companies in the Nasdaq Biotech Index for the measurement period was between the returns of companies in the 65th percentile and the 75th percentile. None of the target amounts of rTSRUs granted in December 2018 vested at December 31, 2020 because our total stockholder return relative to such companies was below the 65th percentile and was a negative return. The rTSRUs granted in December 2019 will not be eligible for vesting until December 31, 2021.

32


The values of the maximum payouts possible for the 2018, 20172020, 2019, and 20162018 rTSRU awards based on the fair value of the rTSRUs at the respective dates of grant and the maximum number of shares issuable under the unit awards based on performance of our common stock are as follows:

 

Fiscal Year Ended September 30,

 

 

2020

 

 

2019

 

 

2018

 

Jay R. Luly, Ph.D.

$

745,558

 

 

$

686,405

 

 

$

1,257,795

 

Yat Sun Or, Ph.D.

$

281,732

 

 

$

156,486

 

 

$

412,913

 

Nathalie Adda, M.D.

$

281,732

 

 

$

156,486

 

 

$

412,913

 

Paul J. Mellett

$

281,732

 

 

$

156,486

 

 

$

381,150

 

Nathaniel S. Gardiner, J.D.

$

281,732

 

 

$

156,486

 

 

$

349,388

 

The amounts in the “Stock Awards” column for fiscal years 2020, 2019, and 2018 reflect the grant date fair values of the rTSRUs granted to our NEOs in December 2019, December 2018 and March 2018, respectively, when the awards were made, and the same is true for the amounts shown in the tables in this note for the grant date fair values of the PSUs and the rTSRUs.

   Maximum ($) 
   2018   2017   2016 

Jay R. Luly, Ph.D.

   1,257,795    1,659,960    809,906 

Yat Sun Or, Ph.D.

   412,913    518,738    244,856 

Nathalie Adda, M.D.

   412,913    518,738    324,162 

Paul J. Mellett

   381,150    484,156    216,602 

Nathaniel S. Gardiner, J.D.

   349,388    461,100    188,350 

The “Stock Awards” column does not include the grant date fair value of the performance share units, or PSUs, awarded during each fiscal year presented because it was not probable at the respective date of grant that the awards would ultimately vest. The PSUs only vest on achievement of specific performance targets that must be achieved over a two-year period ending on December 31 of the second year. A portion of the grant date fair value of a PSU is only recorded in our financial statements, if ever, when it is probable that the corresponding research or development milestone will be achieved. The grant date fair value of PSUs is based on the fair market value of the stock on the date of grant, which is determined to be the closing price of our common stock on that date.  The grant date fair values of the target number of PSUs awarded in 2020, 2019 and 2018 were as follows:

 

Fiscal Year Ended September 30,

 

 

2020

 

 

2019

 

 

2018

 

Jay R. Luly, Ph.D.

$

693,749

 

 

$

647,805

 

 

$

771,507

 

Yat Sun Or, Ph.D.

$

262,154

 

 

$

147,686

 

 

$

253,273

 

Nathalie Adda, M.D.

$

262,154

 

 

$

147,686

 

 

$

253,273

 

Paul J. Mellett

$

262,154

 

 

$

147,686

 

 

$

233,790

 

Nathaniel S. Gardiner, J.D.

$

262,154

 

 

$

147,686

 

 

$

214,307

 

A total of 15% of the target amounts of PSUs granted in March 2018 vested at December 31, 2019, and none of the target amounts of PSUs granted in December 2018 vested at December 31, 2020. The PSUs granted in December 2019 are not eligible for vesting until December 31, 2021.

The values of the maximum payouts possible for the 2018, 20172020, 2019, and 20162018 PSU awards, which are based on the fair market value of our common stock at the respective dates of grant, and the maximum number of shares issuable under thethese unit awards, based on performance against internal research and development objectives arewere as follows:

   Maximum ($) 
   2018   2017   2016 

Jay R. Luly, Ph.D.

   1,157,261    1,292,040    688,860 

Yat Sun Or, Ph.D.

   379,909    403,763    208,260 

Nathalie Adda, M.D.

   379,909    403,763    368,460 

Paul J. Mellett

   350,685    358,900    184,230 

Nathaniel S. Gardiner, J.D.

   321,461    358,900    160,200 

The “Stock Awards” column for fiscal 2018 reflects the grant date fair value of the rTSRUs granted in March 2018 to our NEOs.

The “Stock Awards” column for fiscal 2017 reflects the grant date fair value of the rTSRUs granted in January 2017, as well as the grant date fair value of the time-based RSUs granted in November 2016 that vest 50% in December 2019 and 50% in December 2020, subject to the NEO’s continued employment with Enanta.

The “Stock Awards” for fiscal 2016 reflect the grant date fair value of the rTSRUs granted in December 2015. Also included in fiscal 2016 is the grant date fair value of Dr. Adda’s additional 2016 rTSRU award that was aone-time grant for herpro-rated service during thetwo-year performance period of the rTSRU awards granted to the other executive officers for the period 2015-2016.

 

Fiscal Year Ended September 30,

 

 

2020

 

 

2019

 

 

2018

 

Jay R. Luly, Ph.D.

$

1,040,624

 

 

$

971,707

 

 

$

1,157,261

 

Yat Sun Or, Ph.D.

$

393,231

 

 

$

221,529

 

 

$

379,909

 

Nathalie Adda, M.D.

$

393,231

 

 

$

221,529

 

 

$

379,909

 

Paul J. Mellett

$

393,231

 

 

$

221,529

 

 

$

350,685

 

Nathaniel S. Gardiner, J.D.

$

393,231

 

 

$

221,529

 

 

$

321,461

 

4)

3)

The “Option Awards” column includes awards made in the first quarter of the fiscal year, e.g. awards in November 2019 are shown in the year 2020. The amounts in the “Option Awards” column reflect the grant date fair value of stock options awarded during the fiscal year computed in accordance with the provisions of ASC 718 using the Black-Scholes option-pricing model. Assumptions used in this calculation are included beginning onpage F-23F-19 in Footnote 10 of our 20182020 Form 10-K.

5)

4)

The amounts shown in the“Non-Equity “Non-Equity Incentive Plan Compensation” column represent a prorated blend of the annual variable cash compensation paidearned in the calendar years covering the corresponding fiscal year and earned based on corporate and individual performance during the calendar year ending with the end of our first quarter of the designated fiscal year (e.g. the percentageprorated blend in fiscal year 20182020 was 25% of variable cash compensation for performance in the calendar year ending December 31, 2017)2019 and 75% of variable cash compensation for the calendar year 2020). Variable cash compensation is based on corporate and individual

33


performance against objectives proposed by management and approved by theour Compensation Committee, which makes the final determination regarding the level of achievement against these objectives. The following presents the target bonusvariable compensation percentages applicable to each executive officer for eachthe calendar year bonus paid in the corresponding fiscal year:

 

Calendar Year Target Variable Compensation

 

 

2020

 

 

2019

 

 

2018

 

Jay R. Luly, Ph.D.

65%

 

 

60%

 

 

60%

 

Yat Sun Or, Ph.D.

40%

 

 

40%

 

 

40%

 

Nathalie Adda, M.D.

40%

 

 

40%

 

 

40%

 

Paul J. Mellett

40%

 

 

40%

 

 

40%

 

Nathaniel S. Gardiner, J.D.

40%

 

 

40%

 

 

40%

 

 

   Fiscal Year Target Bonus 
   2018  2017  2016 

Jay R. Luly, Ph.D.

   60  55  55

Yat Sun Or, Ph.D.

   40  40  40

Nathalie Adda, M.D.

   40  40  35

Paul J. Mellett

   40  40  35

Nathaniel S. Gardiner, J.D.

   40  40  35

During the 2016 fiscal year, Dr. Adda receivedpro-rated variable cash compensation based on corporate performance during calendar year 2015 as her employment began with the Company in June 2015.

6)

5)

Includes employer matching contributions under our 401(k) plan of $16,200, $15,900$16,800, $16,500, and $13,250$16,200 for each of our NEOs in fiscal 2018, 20172020, 2019, and 2016,2018, respectively. The table also includes company-paid premiums for group term life insurance, short term disability and accidental death and dismemberment insurance and reimbursement for the cost of long-term disability insurance in the aggregate amounts of $2,371 for fiscal 2020 and $2,651 $2,651for both fiscal 2019 and $2,607fiscal 2018 for each of our NEOs in fiscal 2018, 2017 and 2016, respectively.NEOs.

20182020 Grants of Plan-Based Awards

The following table sets forth certain additional information regarding grants of plan-based awards to our NEOs for our 20182020 fiscal year under our 20122019 Equity Incentive Plan:

 

       Estimated future payouts under
equity incentive plan awards
             
   Grant
Date
   Threshold
(#)
   Target
(#)
   Maximum
(#)
   All other option
awards:
number of
securities
underlying
options (#)
   Exercise
or base
price of
option
awards ($)
   Grant date
fair value
of stock
and option
awards ($)
 

Jay R. Luly, Ph.D.

              

2018 PSUs

   3/1/2018    —      9,900    14,850    —      —      —   

2018 rTSRUs

   3/1/2018    —      9,900    14,850    —      —      838,530 

2018 Option award

   11/17/2018    —      —      —      100,000   $48.52    2,684,490 

Yat Sun Or, Ph.D.

              

2018 PSUs

   3/1/2018    —      3,250    4,875    —      —      —   

2018 rTSRUs

   3/1/2018    —      3,250    4,875    —      —      275,275 

2018 Option award

   11/17/2018    —      —      —      23,500   $48.52    630,855 

Nathalie Adda, M.D.

              

2018 PSUs

   3/1/2018    —      3,250    4,875    —      —      —   

2018 rTSRUs

   3/1/2018    —      3,250    4,875    —      —      275,275 

2018 Option award

   11/17/2018    —      —      —      23,500   $48.52    630,855 

Paul J. Mellett

              

2018 PSUs

   3/1/2018    —      3,000    4,500    —      —      —   

2018 rTSRUs

   3/1/2018    —      3,000    4,500    —      —      254,100 

2018 Option award

   11/17/2018    —      —      —      22,500   $48.52    604,010 

Nathaniel S. Gardiner, J.D.

              

2018 PSUs

   3/1/2018    —      2,750    4,125    —      —      —   

2018 rTSRUs

   3/1/2018    —      2,750    4,125    —      —      232,925 

2018 Option award

   11/17/2018    —      —      —      21,500   $48.52    577,165 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Estimated future payouts under

 

 

 

 

 

 

 

 

 

 

 

 

 

equity incentive plan awards

 

 

All other option awards:

 

 

 

 

 

 

 

 

 

 

Grant

 

Threshold

 

Target

 

 

Maximum

 

 

number of securities

 

 

Exercise or base price

 

 

Grant date fair value of

 

 

Date

 

(#)

 

(#)

 

 

(#)

 

 

underlying options (#)

 

 

of option awards ($)

 

 

stock and option awards ($)

 

Jay R. Luly, Ph.D.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2020 Option award

11/18/2019

 

 

 

 

 

 

 

110,000

 

 

$

63.35

 

 

$

3,598,848

 

2020 PSUs

12/20/2019

 

 

 

10,850

 

 

 

16,275

 

 

 

 

 

 

 

2020 rTSRUs

12/20/2019

 

 

 

10,850

 

 

 

16,275

 

 

 

 

 

 

$

497,039

 

Yat Sun Or, Ph.D.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2020 Option award

11/18/2019

 

 

 

 

 

 

 

30,000

 

 

$

63.35

 

 

$

981,504

 

2020 PSUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

 

2020 rTSRUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

$

187,821

 

Nathalie Adda, M.D.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2020 Option award

11/18/2019

 

 

 

 

 

 

 

30,000

 

 

$

63.35

 

 

$

981,504

 

2020 PSUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

 

2020 rTSRUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

$

187,821

 

Paul J. Mellett

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2020 Option award

11/18/2019

 

 

 

 

 

 

 

30,000

 

 

$

63.35

 

 

$

981,504

 

2020 PSUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

 

2020 rTSRUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

$

187,821

 

Nathaniel S. Gardiner, J.D.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2020 Option award

11/18/2019

 

 

 

 

 

 

 

30,000

 

 

$

63.35

 

 

$

981,504

 

2020 PSUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

 

2020 rTSRUs

12/20/2019

 

 

 

4,100

 

 

 

6,150

 

 

 

 

 

 

$

187,821

 

Performance Unit Awards (“PSUs”)

The fair value of the PSUs granted in fiscal 20182020 was not included in the table above because on the date of grant noneit was not probable that any of the underlying performance milestones were achieved. The PSUs granted in fiscal 20182020 will vest as to percentages of the target number of unit shares only upon achievement of specified milestones within three research and development categories by the end of calendar 2019,2021, with the actual number of unit shares that may

34


be earned ranging from 0% to 150% of the target number. Additional details regarding the specified milestones are set forth earlier in this proxy statement under “EXECUTIVE COMPENSATION – Compensation Discussion and Analysis –Long-Term Equity Incentive Awards - Restricted Stock Units with Performance-Based Vesting.”

The values of the target and maximum payouts possible for the 20182020 PSU awards based on the fair value at the date of grant and the target and maximum number of units issuable are as follows:

  Target   Maximum 

Target

 

 

Maximum

 

Jay R. Luly, Ph.D.

  $771,507   $1,157,261 

$

693,749

 

 

$

1,040,624

 

Yat Sun Or, Ph.D.

  $253,273   $379,909 

$

262,154

 

 

$

393,231

 

Nathalie Adda, M.D.

  $253,273   $379,909 

$

262,154

 

 

$

393,231

 

Paul J. Mellett

  $233,790   $350,685 

$

262,154

 

 

$

393,231

 

Nathaniel S. Gardiner, J.D.

  $214,308   $321,461 

$

262,154

 

 

$

393,231

 

If none of the specified goals within the three research and development categories (“threshold”) areis achieved by the end of calendar 2019,2021, none of the unit shares will vest.

Relative Total Stockholder Return Units (“rTSRUs”)

The rTSRUs granted in the first quarter of fiscal 20182020 will vest as to percentages of the target number of unit shares based on the relative ranking of the total stockholder return of our common stock in relation to the total stockholder return of the component companies in the NASDAQNasdaq Biotech Index over a two yeartwo-year period based on a comparison of average closing stock prices in the last 60 trading days of calendar 20172019 and calendar 2019.2021. The actual number of shares that may be earned under the market-based unit ranges from 0% to 150% of the target number.

The values of the target and maximum payouts possible for the 20182020 rTSRU awards based on the fair value at the date of grant and the target and maximum number of units issuable, based on performance of our common stock are set forth below. These values differ from those for the PSU awards because they are valued based on a Monte Carlo simulation model, as follows:noted in Note 2 to the Summary Compensation Table above:

 

  Target   Maximum 

Target

 

 

Maximum

 

Jay R. Luly, Ph.D.

  $838,530   $1,257,795 

$

497,039

 

 

$

745,559

 

Yat Sun Or, Ph.D.

  $275,275   $412,913 

$

187,821

 

 

$

281,732

 

Nathalie Adda, M.D.

  $275,275   $412,913 

$

187,821

 

 

$

281,732

 

Paul J. Mellett

  $254,100   $381,150 

$

187,821

 

 

$

281,732

 

Nathaniel S. Gardiner, J.D.

  $232,925   $349,388 

$

187,821

 

 

$

281,732

 

If the minimum total return (“threshold”), as approved by theour Compensation Committee, is not achieved by the end of calendar 2019,2021, or if there is no increase in the value of Enanta stock during the two-year period, none of the unit shares will vest.

Stock Options

Each of the option awards has aten-year term which vest quarterly over four years. The aggregate grant date fair value of stock options granted during the fiscal year is computed in accordance with the provisions of ASC 718. The exercise price of the options is equal to the closing price of our common stock on the date of grant.

35


20182020 Options Exercised and Stock Awards Vested

The following table sets forth the value realized by our NEOs from options to purchase common stock exercised by the NEOs during fiscal 20182020 and shares of stock that vested during fiscal 2018.2020. The value realized

per share for options is based on the difference between the exercise price and the fair market value of our common stock on the date the options were exercised. The value realized upon vesting of the stock awards is based on the fair market value of the shares on the settlement date.

 

   Option Awards   Stock Awards (a) 

Name

  Number of
Shares
Acquired on
Exercise (#)
   Value
Realized on
Exercise ($)
   Number of
Shares
Acquired on
Vesting (#)
   Value
Realized on
Vesting ($)
 

Jay R. Luly, Ph.D.

   8,498    715,818    29,337    2,254,402 

Yat Sun Or, Ph.D.

   —      —      8,869    681,538 

Nathalie Adda, M.D.

   17,730    1,058,511    8,528    655,334 

Paul J. Mellett

   6,960    779,780    7,846    602,926 

Nathaniel S. Gardiner, J.D.

   4,300    171,828    6,822    524,237 

 

 

Option Awards

 

 

Stock Awards (1)

 

 

 

Number of Shares

 

 

 

 

 

 

Number of Shares

 

 

 

 

 

 

 

Acquired on Exercise (#)

 

 

Value Realized on Exercise ($)

 

 

Acquired on Vesting (#)

 

 

Value Realized on Vesting ($)

 

Jay R. Luly, Ph.D.

 

 

7,052

 

 

$

309,584

 

 

 

17,895

 

 

$

1,044,303

 

Yat Sun Or, Ph.D.

 

 

 

 

 

 

8,662

 

 

$

527,121

 

Nathalie Adda, M.D.

 

 

 

 

 

 

8,662

 

 

$

527,121

 

Paul J. Mellett

 

 

1,740

 

 

$

86,605

 

 

 

4,200

 

 

$

256,649

 

Nathaniel S. Gardiner, J.D.

 

 

6,258

 

 

$

131,620

 

 

 

8,137

 

 

$

499,422

 

(a)

(1)

These stock awards consist oftwo-year PSUs and rTSRUs as well as RSUs. The two-year PSUs and rTSRUs were granted at the endbeginning of calendar 20152018 for which the performance ended at December 31, 20172019 and that vested and settled in early 2018fiscal 2020. The service-based RSUs, which represent 50% of a one-time award of RSUs granted in November 2016 vested and settled in December 2019. Of the stock awards represented here, 8% of which 71%these shares represented vested PSUs, 55% represented vested rTSRUs and 29%36% represented vested PSUs.RSUs.

36


Outstanding Equity Awards atat Fiscal 20182020 Year-End

The following table summarizes the outstanding equity award holdings of our NEOs as of September 30, 2018:2020:

 

 

 

Option Awards

 

Stock Awards

 

Named Executive Officers

Grant Date

 

Number of Securities Underlying Unexercised Options (# Exercisable)

 

 

Number of Securities Underlying Unexercised Options (# Unexercisable)

 

 

Option Exercise Price ($/Sh)

 

 

Option Expiration Date

 

Number of shares or units of stock that have not vested (#)1

 

 

Market value of shares of units of stock that have not vested ($)2

 

 

Equity incentive plan awards: Number of unearned shares, units or other rights that have not vested (#)3

 

 

 

Equity incentive plan awards: Market or payout value of unearned shares, units or other rights that have not vested ($) 4

 

Jay R. Luly, Ph.D.

6/20/2012

 

 

10,063

 

 

 

 

 

$

11.77

 

 

6/20/2022

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/26/2012

 

 

16,149

 

 

 

 

 

$

14.18

 

 

12/26/2022

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

3/21/2013

 

 

41,763

 

 

 

 

 

$

14.00

 

 

3/21/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/5/2013

 

 

70,000

 

 

 

 

 

$

27.58

 

 

12/5/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/9/2013

 

 

25,000

 

 

 

 

 

$

29.66

 

 

12/9/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2014

 

 

85,250

 

 

 

 

 

$

44.00

 

 

11/20/2024

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2015

 

 

110,000

 

 

 

 

 

$

31.42

 

 

11/20/2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

112,500

 

 

 

7,500

 

 

$

30.00

 

 

11/18/2026

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/17/2017

 

 

68,750

 

 

 

31,250

 

 

$

48.52

 

 

11/17/2027

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/16/2018

 

 

29,750

 

 

 

38,250

 

 

$

81.20

 

 

11/16/2028

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2019

 

 

20,625

 

 

 

89,375

 

 

$

63.35

 

 

11/18/2029

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

7,500

 

 

$

343,350

 

 

 

 

 

 

 

 

 

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

9,650

 

 

(a)

$

441,777

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

9,650

 

 

(b)

$

441,777

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

10,850

 

 

(c)

$

496,713

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

10,850

 

 

(d)

$

496,713

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Yat Sun Or, Ph.D.

6/20/2012

 

 

8,544

 

 

 

 

 

$

11.77

 

 

6/20/2022

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/26/2012

 

 

5,149

 

 

 

 

 

$

14.18

 

 

12/26/2022

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

3/21/2013

 

 

13,925

 

 

 

 

 

$

14.00

 

 

3/21/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/5/2013

 

 

35,000

 

 

 

 

 

$

27.58

 

 

12/5/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/9/2013

 

 

12,500

 

 

 

 

 

$

29.66

 

 

12/9/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2014

 

 

36,500

 

 

 

 

 

$

44.00

 

 

11/20/2024

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2015

 

 

33,000

 

 

 

 

 

$

31.42

 

 

11/20/2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

32,812

 

 

 

2,188

 

 

$

30.00

 

 

11/18/2026

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/17/2017

 

 

16,156

 

 

 

7,344

 

 

$

48.52

 

 

11/17/2027

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/16/2018

 

 

8,750

 

 

 

11,250

 

 

$

81.20

 

 

11/16/2028

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2019

 

 

5,625

 

 

 

24,375

 

 

$

63.35

 

 

11/18/2029

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

5,250

 

 

$

240,345

 

 

 

 

 

 

 

 

 

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,200

 

 

(a)

$

100,716

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,200

 

 

(b)

$

100,716

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(c)

$

187,698

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(d)

$

187,698

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Nathalie Adda, M.D.

6/29/2015

 

 

72,270

 

 

 

 

 

$

43.46

 

 

6/29/2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2015

 

 

16,000

 

 

 

 

 

$

31.42

 

 

11/20/2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

32,812

 

 

 

2,188

 

 

$

30.00

 

 

11/18/2026

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/17/2017

 

 

16,156

 

 

 

7,344

 

 

$

48.52

 

 

11/17/2027

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/16/2018

 

 

8,750

 

 

 

11,250

 

 

$

81.20

 

 

11/16/2028

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2019

 

 

5,625

 

 

 

24,375

 

 

$

63.35

 

 

11/18/2029

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

5,250

 

 

$

240,345

 

 

 

 

 

 

 

 

 

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,200

 

 

(a)

$

100,716

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,200

 

 

(b)

$

100,716

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(c)

$

187,698

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(d)

$

187,698

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

37


 

     Option Awards  Stock Awards 

Named Executive Officers

 Grant Date  Number of
Securities
Underlying
Unexercised
Options (#
Exercisable)
  Number of
Securities
Underlying
Unexercised
Options (#
Unexercisable)
  Option
Exercise
Price
($/Sh)
  Option
Expiration
Date
  Number
of shares
or units
of stock
that
have not
vested
(#)
  Market
value of
shares
of units
of stock
that
have
not
vested
($)
  Equity
incentive
plan awards:
Number of
unearned
shares, units
or other
rights that
have not
vested (#)1
  Equity
incentive
plan awards:
Market or
payout value
of unearned
shares, units
or other
rights that
have not
vested ($)2
 

Jay R. Luly, Ph.D.

  6/20/2012   10,063   —    $11.77   6/20/2022     
  12/26/2012   23,201   —    $14.18   12/26/2022     
  3/21/2013   41,763   —    $14.00   3/21/2023     
  12/05/2013   70,000   —    $27.58   12/5/2023     
  12/09/2013   25,000   —    $29.66   12/9/2023     
  11/20/2014   79,921   5,329  $44.00   11/20/2024     
  11/20/2015   75,625   34,375  $31.42   11/20/2025     
  11/18/2016   52,500   67,500  $30.00   11/18/2026     
  11/17/2017   18,750   81,250  $48.52   11/17/2027     
  11/18/2016         15,000 (a)  $1,281,900 
  1/4/2017         18,000 (b)  $1,538,280 
  1/4/2017         18,000 (c)  $1,538,280 
  3/1/2018         9,900 (d)  $846,054 
  3/1/2018         9,900 (e)  $846,054 

Yat Sun Or, Ph.D.

  6/20/2012   18,793   —    $11.77   6/20/2022     
  12/26/2012   13,921   —    $14.18   12/26/2022     
  3/21/2013   20,881   —    $14.00   3/21/2023     
  12/5/2013   35,000   —    $27.58   12/5/2023     
  12/9/2013   12,500   —    $29.66   12/9/2023     
  11/20/2014   34,218   2,282  $44.00   11/20/2024     
  11/20/2015   22,687   10,313  $31.42   11/20/2025     
  11/18/2016   15,312   19,688  $30.00   11/18/2026     
  11/17/2017   4,406   19,094  $48.52   11/17/2027     
  11/18/2016         10,500 (a)  $897,330 
  1/4/2017         5,625 (b)  $480,713 
  1/4/2017         5,625 (c)  $480,713 
  3/1/2018         3,250 (d)  $277,745 
  3/1/2018         3,250 (e)  $277,745 

 

 

 

Option Awards

 

Stock Awards

 

Named Executive Officers

Grant Date

 

Number of Securities Underlying Unexercised Options (# Exercisable)

 

 

Number of Securities Underlying Unexercised Options (# Unexercisable)

 

 

Option Exercise Price ($/Sh)

 

 

Option Expiration Date

 

Number of shares or units of stock that have not vested (#)1

 

 

Market value of shares of units of stock that have not vested ($)2

 

 

Equity incentive plan awards: Number of unearned shares, units or other rights that have not vested (#)3

 

 

 

Equity incentive plan awards: Market or payout value of unearned shares, units or other rights that have not vested ($) 4

 

Paul J. Mellett (5)

4/15/2011

 

 

3,480

 

 

 

 

 

$

2.54

 

 

12/31/2020

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

6/20/2012

 

 

3,480

 

 

 

 

 

$

11.77

 

 

6/20/2022

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/26/2012

 

 

4,148

 

 

 

 

 

$

14.18

 

 

12/26/2022

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1/17/2013

 

 

2,812

 

 

 

 

 

$

14.18

 

 

1/17/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

3/21/2013

 

 

10,440

 

 

 

 

 

$

14.00

 

 

3/21/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/5/2013

 

 

17,500

 

 

 

 

 

$

27.58

 

 

12/5/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

12/9/2013

 

 

6,250

 

 

 

 

 

$

29.66

 

 

12/9/2023

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2014

 

 

16,250

 

 

 

 

 

$

44.00

 

 

11/20/2024

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2015

 

 

14,999

 

 

 

 

 

$

31.42

 

 

11/20/2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

14,061

 

 

 

938

 

 

$

30.00

 

 

11/18/2026

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/17/2017

 

 

7,734

 

 

 

3,516

 

 

$

48.52

 

 

11/17/2027

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/16/2018

 

 

4,156

 

 

 

5,344

 

 

$

81.20

 

 

11/16/2028

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2019

 

 

5,625

 

 

 

24,375

 

 

$

63.35

 

 

11/18/2029

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,625

 

 

$

120,173

 

 

 

 

 

 

 

 

 

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1,100

 

 

(a)

$

50,358

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1,100

 

 

(b)

$

50,358

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(c)

$

187,698

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(d)

$

187,698

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Nathaniel S. Gardiner, J.D.

5/9/2014

 

 

70,976

 

 

 

 

 

$

34.70

 

 

5/9/2024

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2014

 

 

27,500

 

 

 

 

 

$

44.00

 

 

11/20/2024

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/20/2015

 

 

19,818

 

 

 

 

 

$

31.42

 

 

11/20/2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

13,771

 

 

 

1,563

 

 

$

30.00

 

 

11/18/2026

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/17/2017

 

 

14,781

 

 

 

6,719

 

 

$

48.52

 

 

11/17/2027

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/16/2018

 

 

7,875

 

 

 

10,125

 

 

$

81.20

 

 

11/16/2028

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2019

 

 

5,625

 

 

 

24,375

 

 

$

63.35

 

 

11/18/2029

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

11/18/2016

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

5,250

 

 

$

240,345

 

 

 

 

 

 

 

 

 

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,200

 

 

(a)

$

100,716

 

 

12/20/2018

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,200

 

 

(b)

$

100,716

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(c)

$

187,698

 

 

12/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4,100

 

 

(d)

$

187,698

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

     Option Awards  Stock Awards 

Named Executive Officers

 Grant Date  Number of
Securities
Underlying
Unexercised
Options (#
Exercisable)
  Number of
Securities
Underlying
Unexercised
Options (#
Unexercisable)
  Option
Exercise
Price
($/Sh)
  Option
Expiration
Date
  Number
of shares
or units
of stock
that
have not
vested
(#)
  Market
value of
shares
of units
of stock
that
have
not
vested
($)
  Equity
incentive
plan awards:
Number of
unearned
shares, units
or other
rights that
have not
vested (#)1
  Equity
incentive
plan awards:
Market or
payout value
of unearned
shares, units
or other
rights that
have not
vested ($)2
 

Nathalie Adda, M.D.

  6/29/2015   55,395   16,875  $43.46   6/29/2025     
  11/20/2015   11,000   5,000  $31.42   11/20/2025     
  11/18/2016   15,312   19,688  $30.00   11/18/2026     
  11/17/2017   4,406   19,094  $48.52   11/17/2027     
  11/18/2016         10,500 (a)  $897,330 
  1/4/2017         5,625 (b)  $480,713 
  1/4/2017         5,625 (c)  $480,713 
  3/1/2018         3,250 (d)  $277,745 
  3/1/2018         3,250 (e)  $277,745 

Paul J. Mellett

  3/5/2009   6,960   —    $1.51   3/5/2019     
  5/25/2010   3,480   —    $1.21   5/25/2020     
  4/15/2011   6,960   —    $2.54   12/31/2020     
  6/20/2012   6,960   —    $11.77   6/20/2022     
  12/26/2012   8,296   —    $14.18   12/26/2022     
  1/17/2013   5,624   —    $14.18   1/17/2023     
  3/21/2013   20,881   —    $14.00   3/21/2023     
  12/5/2013   35,000   —    $27.58   12/5/2023     
  12/9/2013   12,500   —    $29.66   12/9/2023     
  11/20/2014   30,468   2,032  $44.00   11/20/2024     
  11/20/2015   20,625   9,375  $31.42   11/20/2025     
  11/18/2016   13,125   16,875  $30.00   11/18/2026     
  11/17/2017   4,218   18,282  $48.52   11/17/2027     
  11/18/2016         10,500 (a)  $897,330 
  1/4/2017         5,250 (b)  $448,665 
  1/4/2017         5,250 (c)  $448,665 
  3/1/2018         3,000 (d)  $256,380 
  3/1/2018         3,000 (e)  $256,380 

Nathaniel S. Gardiner

  5/9/2014   78,200   —    $34.70   5/9/2024     
  11/20/2014   25,781   1,719  $44.00   11/20/2024     
  11/20/2015   17,531   7,969  $31.42   11/20/2025     
  11/18/2016   10,937   14,063  $30.00   11/18/2026     
  11/17/2017   4,031   17,469  $48.52   11/17/2027     
  11/18/2016         10,500 (a)  $897,330 
  1/4/2017         5,000 (b)  $427,300 
  1/4/2017         5,000 (c)  $427,300 
  3/1/2018         2,750 (d)  $235,015 
  3/1/2018         2,750 (e)  $235,015 

 

(1)

The awards in this column represent restricted stock units (RSUs) subject only to service-based vesting. These RSUs were to vest in December 2020.

(2)

The market value of these awards set forth in this table is based on the number of awards shown multiplied by the closing price of our common stock on September 30, 2020 ($45.78), as reported by the Nasdaq Global Select Market.

(3)

The awards included in this column represent performance share units (PSUs), and relative total stockholder return units (rTSRUs) or restricted stock units (RSUs). This column shows the target number of shares that may be earned. For PSUs and rTSRUs granted on during fiscal 2017, the actual number of shares that may be earned ranges from 0% to 200% of the target number. For PSUs and rTSRUs granted on during fiscal 2018, theThe actual number of shares that may be earned ranges from 0% to 150% of the target number.

 

(a)

Subject to the named executive’s continued employment with Enanta, the RSUs granted will vest as to 50% of the units in December 2019 and 50% in December 2020.(a)

(b)

These PSUs were to vest as to percentages of the target number of unit shares only upon Enanta’s achievement of specified milestones within three research and development categories on or before December 31, 2018,2020, and will

38


settle in February 2020,2021, subject to the NEO’s continued employment with Enanta. ThereAdditional details regarding the specified milestones are two or more objectivesset forth earlier in each category related to our three principal disease areas of RSV, NASH/PBCthis proxy statement under “EXECUTIVE COMPENSATION – Compensation Discussion and HBV. Any of the objectives could trigger vesting as to its milestone category.Analysis – Long-Term Equity Incentive Awards – Restricted Stock Units with Performance-Based Vesting.” The actual number of unit shares that could be earned for achievement of one or more milestones ranged from 80%15% to 200%150% of the target number shown. As of December 31, 2018, the only objective2020, none of these PSUs vested.

that had been achieved was related to the advancement ofEDP-938 for RSV, which vested 80% of the target number of shares subject to these PSUs.
(c)

(b)

These rTSRUs willwere to vest based upon the relative ranking of the total stockholder return, or TSR, of Enanta’s common stock in relation to the TSR of each of the component companies in the NASDAQ Biotech Index over atwo-year period based on a comparison of average closing stock prices in the 60 trading days prior to December 20162018 and December 2018, and will settle in February 2019, subject to the NEO’s continued employment with Enanta.2020. As of December 31, 2020, none of these rTSRUs vested.

(d)

(c)

These PSUs will vest as to percentages of the target number of unit shares only upon Enanta’s achievement of specified milestones within three research and development categories on or before December 31, 2019,2021, and will settle in February 2020,2022, subject to the NEO’s continued employment with Enanta. The actual number of unit shares that may be earned range from 0% to 150% of the target number shown. Additional details regarding the specified milestones are set forth earlier in this proxy statement under “EXECUTIVE COMPENSATION – Compensation Discussion and Analysis –Long-Term Equity Incentive Awards - Restricted Stock Units with Performance-Based Vesting.”

(e)

(d)

These rTSRUs will vest based upon the relative ranking of the total stockholder return, or TSR, of Enanta’s common stock in relation to the TSR of each of the component companies in the NASDAQ Biotech Index over atwo-year period based on a comparison of average closing stock prices in the 60 trading days prior to December 20172019 and December 2019,2021, and will settle in February 2020,2022, subject to the NEO’s continued employment with Enanta.

(2)

(4)

The market value of thesethe awards set forth in this tablecolumn is based on the target number of awards shown multiplied by the closing price of our common stock on September 30, 20182020 ($85.46)45.78), as reported by the Nasdaq Global Select Market.

(5)

Pursuant to a qualifying domestic relations order issued on November 19, 2019, one half of all Enanta securities held by Mr. Mellett on September 30, 2019 were transferred to his former spouse.

Potential Payments Upon Termination, Including Termination After a Change in Control Transaction

If Dr. Luly is terminated involuntarily without cause or constructively terminated, and such termination occurs within twelve months of a change in control transaction, these terms as defined in the executive employment agreements, he is entitled to the following: (i) a lump sum payment in an amount equal to the higher of (x) eighteen (18) months of his then current base salary or (y) eighteen (18) months of his base salary immediately prior to the effective date of the change in control, (ii) a lump sum payment equal to one hundred fifty percent (150%) of the target annual bonus for the period in which his employment is terminated and (iii) a continuation of benefit coverage for up to eighteen (18) months.

If any of Dr. Or, Dr. Adda, Mr. Mellett or Mr. Gardiner is terminated involuntarily without cause or constructively terminated, and such termination occurs within twelve months of a change in control transaction, these terms as defined in the agreements, then each is entitled to following: (i) a lump sum payment in an amount equal to the higher of (x) twelve (12) months of his or her then current base salary or (y) twelve (12) months of his base salary immediately prior to the effective date of the change in control, (ii) a lump sum payment equal to one hundred percent (100%) of the target annual bonus for the period in which his or her employment is terminated and (iii) a continuation of benefit coverage for up to twelve (12) months.

If Dr. Luly is terminated involuntarily without cause other than within twelve (12) months of a change in control transaction or if he voluntarily terminates his employment for good reason, these terms as defined in the agreements, he is entitled to the following: (i) a lump sum payment in an amount equal to twelve (12) months of his then currentbase salary and (ii) a lump sum payment in an amount equal to one hundred percent (100%) of the target annual bonus for the period in which his employment is terminated and (iii) continuation of benefit coverage for up to twelve (12) months.

If any of Dr. Or, Dr. Adda, Mr. Mellett or Mr. Gardiner is terminated involuntarily without cause other than within twelve (12) months of a change in control transaction or voluntarily terminates his employment for good reason, these terms as defined in the agreements, then each is entitled to the following: (i) a lump sum payment in

an amount equal to six (6) months of his or her then current base salary and (ii) continuation of benefit coverage for up to six (6) months.

39


In addition, if any of Dr. Luly, Dr. Or, Dr. Adda, Mr. Mellett or Mr. Gardiner is involuntary terminated without cause or is constructively terminated, and such termination occurs within twelve months of a change of control transaction, these terms as defined in the agreements, all unvested stock options and restricted stock units granted to that executive shall immediately become fully vested and exercisable.exercisable or become vested and settle, as the case may be, and all unvested performance share units shall vest and issue with respect to the target number of shares.

The following tables shows the potential payments due to each of our NEOs (i) upon termination of employment prior to a change in control and (ii) upon termination of employment within 12 months following a change of control; assuming such termination were to have occurred as of September 30, 2018.2020.

 

   Termination Without Cause(1)
Not in Connection with a Change of Control
 

Named Executive Officers

  Salary
($)
   Bonus
($)(2)
   Benefits
($)(3)
   Other
($)(4)
   Value of
Modified
Equity
Awards
($)(5)
   Total ($) 

Jay R. Luly, Ph.D.

   617,300      370,383      2,370      26,587    —      990,050 

Yat Sun Or, Ph.D.

   217,800      87,120      12,779      19,759    —      317,699 

Nathalie Adda, M.D.

   213,450      85,380      6,753      16,004    —      305,583 

Paul J. Mellett

   201,050      80,420      12,779      12,011    —      294,249 

Nathaniel S. Gardiner, J.D.

   204,100      81,640      12,779      2,324    —      298,519 

 

 

Termination Without Cause(1)

Not in Connection with a Change of Control

 

 

 

Salary ($)

 

 

Bonus ($)(2)

 

 

Benefits ($)(3)

 

 

Other ($)(4)

 

 

Value of Modified Equity Awards ($)(5)

 

 

Total ($)

 

Jay R. Luly, Ph.D.

 

 

672,750

 

 

 

437,288

 

 

 

24,709

 

 

 

101,822

 

 

 

 

 

 

1,236,568

 

Yat Sun Or, Ph.D.

 

 

238,050

 

 

 

 

 

 

12,354

 

 

 

50,780

 

 

 

 

 

 

301,184

 

Nathalie Adda, M.D.

 

 

227,700

 

 

 

 

 

 

5,934

 

 

 

22,208

 

 

 

 

 

 

255,842

 

Paul J. Mellett

 

 

214,763

 

 

 

 

 

 

12,354

 

 

 

44,176

 

 

 

 

 

 

271,293

 

Nathaniel S. Gardiner, J.D.

 

 

217,350

 

 

 

 

 

 

12,354

 

 

 

29,503

 

 

 

 

 

 

259,207

 

(1)

“Cause” is defined as a vote of our Board of Directors to dismiss the NEO as a result of (i) any act of the NEO constituting criminal financial dishonesty against Enanta; (ii) the NEO’s engagement in any other act of dishonesty, fraud, intentional misrepresentation, moral turpitude, illegality or harassment determined in good faith by our Board of Directors to be reasonably likely to adversely affect Enanta’s business or reputation or negligently expose Enanta to civil or criminal liability; or (iii) the NEO’s repeated failure to follow the directives of the Board.

(2)

Represents lump sum payment made as of date of termination based on 100% of the NEO’sCEO’s target bonus.

(3)

Consists of health and dental benefits and life insurance coverage. The value is based upon the type of insurance coverage we carried for each executive officer as of September 30, 20182020 and is valued at the premiums in effect on September 30, 2018.2020.

(4)

Represents accrued vacation pay due to the executive officer as of September 30, 2018.2020.

(5)

No options, or restricted stock units or performance share units would vest as a result of the termination of the executive officer’s employment without cause not in connection with a change of control.

40


 

   Termination Without Cause(1)
Following a Change of Control
 

Named Executive Officers

  Salary
($)
   Bonus
($)(2)
   Benefits
($)(3)
   Other
($)(4)
   Value of
Modified
Equity
Awards
($)(5)
   Total
($)
 

Jay R. Luly, Ph.D.

   925,950    555,570    3,556    26,587    14,874,058    16,385,720 

Yat Sun Or, Ph.D.

   435,600    174,240    25,557    9,759    4,863,400    5,518,556 

Nathalie Adda, M.D.

   426,900    170,760    13,505    6,004    5,190,424    5,817,593 

Paul J. Mellett

   402,100    160,840    25,557    2,011    4,509,516    5,110,024 

Nathaniel S. Gardiner, J.D.

   408,200    163,280    25,557    2,324    4,149,113    4,748,474 

 

 

Termination Without Cause(1)

Following a Change of Control

 

 

 

Salary ($)

 

 

Bonus ($)(2)

 

 

Benefits ($)(3)

 

 

Other ($)(4)

 

 

Value of Modified Equity Awards ($)(5)

 

 

Total ($)

 

Jay R. Luly, Ph.D.

 

 

1,009,125

 

 

 

655,931

 

 

 

37,063

 

 

 

101,822

 

 

 

2,338,680

 

 

 

4,142,621

 

Yat Sun Or, Ph.D.

 

 

476,100

 

 

 

190,440

 

 

 

24,709

 

 

 

50,780

 

 

 

851,700

 

 

 

1,593,729

 

Nathalie Adda, M.D.

 

 

455,400

 

 

 

182,160

 

 

 

11,867

 

 

 

22,208

 

 

 

851,700

 

 

 

1,523,335

 

Paul J. Mellett

 

 

429,525

 

 

 

171,810

 

 

 

24,709

 

 

 

44,176

 

 

 

611,086

 

 

 

1,281,306

 

Nathaniel S. Gardiner, J.D.

 

 

434,700

 

 

 

173,880

 

 

 

24,709

 

 

 

29,503

 

 

 

841,837

 

 

 

1,504,629

 

(1)

“Change in control” is defined as (a) the acquisition of 50% or more of our common stock (including shares convertible into common stock) by any person, entity or “group” (as such term is defined in Section 13(d) or 14(d)(2) of the Securities Exchange Act of 1934, as amended); (b) a change in the majority of the directors

on the board of directors being directors who were not nominated by the incumbent board; (c) a merger or similar combination after which 50% or more of our voting stock or any other surviving corporation that is a successor to us is not held by the persons having beneficial ownership of us immediately prior to such merger or combination, or (d) the sale of all or substantially all of our assets.

(2)

Amount represents 100% of the executive’s target bonus for the fiscal year in which termination of employment occurs,pro-rated by the number of calendar days the executive was employed during such fiscal year and 100% of the executive’s target bonus for the severance period covered.occurs. In the case of our CEO, the amount represents 150% of his target bonus.

(3)

Consists of health, dental and vision benefits and life insurance coverage. The value is based upon the type of insurance coverage we carried for each executive officer as of September 30, 20182020 and is valued at the premiums in effect on September 30, 2018.2020.

(4)

Represents accrued vacation pay due to the executive officer as of September 30, 2018.2020.

(5)

Represents the intrinsic value, as of September 30, 2018,2020, of all unvested stock options, and restricted stock units and performance share units that would vest as a result of the termination of the executive officer’s employment as of September 30, 20182020 in connection with a change of control.

CEO Pay Ratio

In accordance with Section 953(b) of the Dodd-Frank Act and Item 402(u) of Regulation S-K, we are required to disclose the ratio of the annual total compensation of our principal executive officer to the median of the annual total compensation of all of our employees other than our principal executive officer. For fiscal 2020 the annual total compensation for Jay R. Luly, Ph.D., our Chief Executive Officer, as reported in our Summary Compensation Table, was $5,197,837, and the annual total compensation for our median employee was $232,629, resulting in an estimated pay ratio of approximately 22:1.

We identified the median employee as of September 30, 2020, by aggregating for each employee employed on that date (i) base salary or wages actually paid in fiscal 2020, (ii) cash incentive compensation actually paid in fiscal 2020, (iii) the grant date fair value of equity awards granted in fiscal 2020 determined in accordance with FASB ASC Topic 718, and (iv) the company-paid 401(k) Plan contribution made during fiscal year 2020. We chose this methodology because we believed it was reasonably representative of our employee compensation. We then ranked our employees from lowest to highest using this compensation measure. This calculation was performed for all of our employees who were employed on September 30, 2020, excluding Dr. Luly, which totaled 139 employees, all of whom are based in the United States. Since that resulted in an odd number of employees, we selected the employee ranked 70th on the list as our “median employee” for purposes of calculating the pay ratio and then determined that employee’s annual total compensation in the same manner as we determined Dr. Luly’s compensation for purposes of the Summary Compensation Table.

41


DIRECTOR COMPENSATIONCOMPENSATION

The following table summarizes compensation paid to ournon-employee directors during or with respect to the fiscal year ended September 30, 2018.2020.

 

Non-Employee Directors:

  Fees
Earned
or Paid
in Cash
($)
   Option
Awards
($)(1)(2)
   All Other
Compensation
($)
   Total ($) 

Stephen Buckley, Jr.

   65,000    306,690    —      371,690 

Bruce L.A. Carter, Ph.D.

   87,500    306,690    —      394,190 

George S. Golumbeski, Ph.D.

   60,000    306,690    —      366,690 

Kristine Peterson

   52,500    153,345    —      205,845 

Lesley Russell, MBChB, MRCP

   55,000    306,690    —      361,690 

Terry C. Vance

   67,500    306,690    —      374,190 

Employee Directors:

        

Jay R. Luly, Ph.D.(3)

   —      —      —      —   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Non-Employee Directors:

 

Fees Earned or Paid in Cash ($)

 

 

Option Awards ($)(1)(2)

 

 

All Other Compensation ($)

 

 

Total ($)

 

Bruce L.A. Carter, Ph.D.

 

 

95,000

 

 

 

235,920

 

 

 

 

 

 

330,920

 

Mark G. Foletta

 

 

17,884

 

 

 

401,475

 

 

 

 

 

 

419,359

 

George S. Golumbeski, Ph.D.

 

 

64,375

 

 

 

235,920

 

 

 

 

 

 

300,295

 

Kristine Peterson

 

 

58,125

 

 

 

235,920

 

 

 

 

 

 

294,045

 

Lesley Russell, MBChB, MRCP

 

 

60,000

 

 

 

235,920

 

 

 

 

 

 

295,920

 

Terry C. Vance

 

 

72,500

 

 

 

235,920

 

 

 

 

 

 

308,420

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Employee Directors:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Jay R. Luly, Ph.D.(3)

 

 

 

 

 

 

 

 

 

 

 

 

(1)

Amounts shown represent the aggregate grant date fair value of the option awards granted on February 28, 201826, 2020 to ournon-employee directors at the time of the 2020 annual meeting and option awards granted to Mark G. Foletta, our non-employee director elected on June 29, 2020. These grant date fair values were computed in accordance with FASB Topic ASC 718. No other equity awards were granted to our non-employee directors in fiscal 2018. These amounts do not correspond to the actual value that will be recognized by thenon-employee director with respect to such awards. The assumptions used in the valuation of these awards are consistent with the valuation methodologies specified in the notes to our financial statements included in our 20182020 Form10-K.

(2)

In 2018,2020, each of ournon-employee directors at the time of the 2020 annual meeting was awarded an option to purchase 7,50010,000 shares, with the exceptionwhich vests monthly until our next annual meeting of Ms. Peterson, whostockholders. In June 2020, Mark G. Foletta was elected to the Board of Directors effective September 11, 2017serve as a non-employee director and was therefore awarded anreceived a stock option to purchase 3,75017,000 shares, based on herpro-rated service through the 2018 Annual Meeting Date.which vests monthly over three years.

The following sets forth the aggregate number of shares underlying outstanding options as of September 30, 20182020 for each director included in the table:

Director

Option Shares
Outstanding

Stephen Buckley, Jr.

45,561

Bruce L.A. Carter, Ph.D.

36,280

42,000

Mark G. Foletta

17,000

George S. Golumbeski, Ph.D.

36,280

28,500

Kristine Peterson

16,250

31,250

Lesley Russell, MBChB, MRCP

20,000

35,000

Terry C. Vance

37,440

52,440

Jay R. Luly, Ph.D.*

 

*

Excludes outstanding options to purchase an aggregate 585,277756,225 shares awarded to Dr. Luly in his capacity as President and Chief Executive Officer of Enanta, outstanding restricted stock units for 15,0007,500 shares with service-based vesting, which were vested and issued on December 16, 2020, and outstanding PSUs and rTSRUs for an aggregate of 55,80041,000 shares, which is the target number of shares that may be earned by Dr. Luly under various unit awards.

(3)

Dr. Luly receives no compensation for his service on the Board. All of his compensation is described above in this Proxy Statementproxy statement under the heading “Executive Compensation.Compensation – Summary Compensation Table.

42


Director Compensation Policy

Ournon-employee directors received an annual retainer of $40,000$45,000 during 2018.2020. The Chairman of our Board of Directors also received an additional retainer of $35,000.$30,000. In addition, allnon-employee directors who served on one or more committees received the following committee fees effective January 1, 2018:fees:

 

Committee

  Chair   Other Member 

 

Chair

 

 

Other Member

 

Audit Committee

  $20,000   $10,000 

 

$

20,000

 

 

$

10,000

 

Compensation Committee

  $15,000   $7,500 

 

$

15,000

 

 

$

7,500

 

Nominating and Corporate Governance Committee

  $10,000   $5,000 

 

$

10,000

 

 

$

5,000

 

Other than the annual retainers and committee fees described above,non-employee directors were not entitled to receive any cash fees in connection with their service on our Board in 2018.2020. Equity awards to ournon-employee directors are made on the date of our annual meeting of stockholders and, in the case of new directors, when they join our board of directors. At our 20182020 annual meeting of stockholders, eachnon-employee director who had served at least six months prior to the annual meeting was awarded an option to purchase 7,50010,000 shares, vesting monthly over the year of service until the next annual meeting. Any director who had served less than six months prior to the annual meeting was awarded an option to purchase 3,750 shares. Any new director is entitled togranted an option award with respect to 12,500 shares upon joining our board of directors, which vestswould typically be approximately 1.7 times the most recent annual grant to non-employee directors and would vest monthly over three years.

In November 2018, based on a review ofnon-employee director compensation among our peer group companies and the recommendation of our compensation consultant and theour Compensation Committee, our Board approved limitations onnon-employee director compensation, which are set forth in our 2019 Equity Plan. These limitations, which apply to total annual compensation, including annual retainer, committee fees and equity awards, are $900,000 in the year of initial election (when an initial equity award is granted) and $600,000 for each year thereafter.  In connection with that review, beginning on January 1, 2019, the Compensation Committee has approved a recommendation to our Board that the annual retainer be increased to $45,000 and, at the suggestion of ournon-executive Chairman of the Board, that his additional retainer be reduced to $30,000.

43


AUDIT COMMITTEECOMMITTEE REPORT

The following is the report of the Audit Committee with respect to Enanta’s audited financial statements for the year ended September 30, 2018.2020.

The purpose of the Audit Committee is to assist the Board in fulfilling its responsibility to oversee Enanta’s accounting and financial reporting, internal controls and audit functions. The Audit Committee Charter describes in greater detail the full responsibilities of the Committee and is available in the “Investors – Corporate Governance” section of our website atwww.enanta.com. The Audit Committee is comprised entirely of independent directors as defined by applicable Nasdaq Stock Market standards.

Management is responsible for our internal controls and the financial reporting process. PricewaterhouseCoopers LLP, our independent registered public accounting firm, is responsible for performing an independent audit of our consolidated financial statements in accordance with the standards established by the Public Company Accounting Oversight Board (United States) and issuing a report thereon. The Committee’s responsibility is to monitor these processes. The Audit Committee has reviewed and discussed the consolidated financial statements with management and PricewaterhouseCoopers LLP.

In the course of its oversight of Enanta’s financial reporting process, the Audit Committee:

reviewed and discussed with management and PricewaterhouseCoopers LLP Enanta’s audited financial statements for the fiscal year ended September 30, 2018;2020;

discussed with PricewaterhouseCoopers LLP the matters required to be discussed by Public Company Accounting Oversight Board Auditing Standard No. 16, Communications with Audit Committees;

discussed with PricewaterhouseCoopers LLP the matters required to be discussed by Public Company Accounting Oversight Board Auditing Standard No. 16,Communications with Audit Committees;

received written disclosures and the letter from PricewaterhouseCoopers LLP required by applicable requirements of the Public Company Accounting Oversight Board regarding the independent accountant’s communications with the Audit Committee concerning independence;

reviewed with management and PricewaterhouseCoopers LLP Enanta’s critical accounting policies;

discussed with management the quality and adequacy of Enanta’s internal controls;

discussed with PricewaterhouseCoopers LLP any relationships that may impact their objectivity and independence; and

considered whether the provision ofnon-audit services by PricewaterhouseCoopers LLP is compatible with maintaining its independence.

Based on the foregoing review and discussions, the Committee recommended to the Board of Directors that the audited financial statements be included in Enanta’s Annual Report on Form10-K for the year ended September 30, 20182020 for filing with the Securities and Exchange Commission.

By the Audit Committee,

Stephen Buckley, Jr.,Mark G. Foletta, Chair

Lesley Russell, MBChB, MRCP

Terry C. Vance

January 18, 2019

21, 2021

44


Audit Fees

PricewaterhouseCoopers LLP, an independent registered public accounting firm, audited our financial statements for the year ended September 30, 2018.2020. The Audit Committee, under delegated authority of the Board of Directors, has appointed PricewaterhouseCoopers LLP to serve as our independent registered public accounting firm for the fiscal year ending September 30, 2019.2021. Representatives of PricewaterhouseCoopers LLP are expected to attend the annual meeting to respond to appropriate questions, and they will have the opportunity to make a statement if they desire.

The aggregate fees for audit and other services provided by PricewaterhouseCoopers LLP for fiscal years 20182020 and 20172019 are as follows:

 

   2018   2017 

Audit Fees(1)

  $642,500   $470,000 

Tax Fees(2)

   95,596    54,682 

All Other Fees(3)

   2,756    114,715 
  

 

 

   

 

 

 

Total

  $740,852   $639,397 
  

 

 

   

 

 

 

 

 

2020

 

 

2019

 

Audit Fees(1)

 

$

733,135

 

 

$

684,500

 

Tax Fees(2)

 

 

101,245

 

 

 

138,500

 

All Other Fees(3)

 

 

2,756

 

 

 

77,756

 

Total

 

$

837,136

 

 

$

900,756

 

(1)

Audit fees represent fees for professional services provided in connection with the audit of our financial statements, audit of our internal control over financial reporting, (fiscal year 2018 only), review of our quarterly financial statements and audit services provided in connection with other statutory or regulatory filings.

(2)

Tax fees were for services related to (a) tax compliance including sales and use taxes and (b) tax planning. The 20182020 tax fees consisted of $32,300$35,000 for tax compliance and $63,296$66,245 for tax planning and assistance with an IRSa state income tax audit. The 20172019 tax fees consisted of $51,000$33,500 for tax compliance and $3,682$105,000 for tax planning for equity grants.and assistance with a state income tax audit.

(3)

All other fees for 2018 consist of a2020 relate technical research material feefees of $2,756. The 2017All other fees relate to feesfor 2019 consist of $75,000 for a royalty audit of $112,015 and a technical research material feefees of $2,700.$2,756.

Our Audit Committee has adopted procedures requiring thepre-approval of allnon-audit (including tax) services performed by our independent registered public accounting firm in order to assure that these services do not impair the auditor’s independence. These procedures generally approve the performance of specific services subject to a cost limit for all such services. This general approval is to be reviewed, and if necessary modified, at least annually. Management must obtain the specific prior approval of the Audit Committee for each engagement of the independent registered public accounting firm to perform other audit-related or othernon-audit services. For engagements for audit-related ortax-related services within a specified dollar limit, the Chair of the Audit Committee has authority to provide such prior approval, and he reports to the full committee whenever he has exercised that authority. The Audit Committee does not delegate its responsibility to approve services performed by the independent registered public accounting firm to any member of management.

The standard applied by the Audit Committee in determining whether to grant approval of any type ofnon- audit non-audit service, or of any specific engagement to perform anon-audit service, is whether the services to be performed, the compensation to be paid therefore and other related factors are consistent with the independent registered public accounting firm’s independence under guidelines of the SEC and applicable professional standards. Relevant considerations include whether the work product is likely to be subject to, or implicated in, audit procedures during the audit of our financial statements, whether the independent registered public accounting firm would be functioning in the role of management or in an advocacy role, whether the independent registered public accounting firm’s performance of the service would enhance our ability to manage or control risk or improve audit quality, whether such performance would increase efficiency because of the independent registered public accounting firm’s familiarity with our business, personnel, culture, systems, risk profile and other factors, and whether the amount of fees involved, or thenon-audit services portion of the total fees payable to the independent registered public accounting firm in the period, would tend to reduce the independent registered public accounting firm’s ability to exercise independent judgment in performing the audit.

45


STOCKHOLDER MATTERS

Stockholder Recommendations for Director Nominations

Any stockholder wishing to recommend a director candidate for consideration by the Nominating and Corporate Governance Committee should provide the following information to the Chair of the Nominating and Corporate Governance Committee, Enanta Pharmaceuticals, Inc., 500 Arsenal Street, Watertown, Massachusetts 02472:

 

(a)

a brief statement outlining the reasons the nominee would be an effective director for Enanta;

 

(b)

(i) the name, age, and business and residence addresses of the candidate, (ii) the principal occupation or employment of the candidate for the past five years, as well as information about any other Board of Directors and board committees on which the candidate has served during that period, (iii) the number of shares of Enanta stock, if any, beneficially owned by the candidate and (iv) details of any business or other significant relationship the candidate has ever had with Enanta;

 

(c)

(i) the stockholder’s name and record address and the name and address of the beneficial owner of Enanta shares, if any, on whose behalf the proposal is made and (ii) the number of shares of Enanta stock that the stockholder and any such other beneficial owner beneficially own; and

 

(d)

the other information specified in Enanta’s Bylaws as then in effect. The Committee may seek further information from or about the stockholder making the recommendation, the candidate, or any such other beneficial owner, including information about all business and other relationships between the candidate and the stockholder and between the candidate and any such other beneficial owner.

Other Stockholder Proposals

Any stockholder proposing to bring any business other than a director candidate before an annual meeting of stockholders, which business must relate to a proper matter under Delaware law for stockholder action, must provide the following information to the Chair of the Nominating and Corporate Governance Committee:

 

(a)

a brief description of the business desired to be brought before the annual meeting;

 

(b)

the text of the proposal (including the exact text of any resolutions proposed for consideration and, in the event that such business includes a proposal to amend the bylaws, the exact text of the proposed amendment);

 

(c)

the reasons for conducting such business at the annual meeting;

 

(d)

the proposing stockholder’s name and record address and the name and address of the beneficial owner of Enanta shares, if any, on whose behalf the proposal is made; and

 

(e)

the other information specified in Enanta’s Bylaws as then in effect.

Deadline for Stockholder Proposals and Director Nominations

In order for a stockholder proposal to be considered for inclusion in Enanta’s proxy materials for the annual meeting of our stockholders to be held in 20202022 (the “2020“2022 Annual Meeting”), it must be received by Enanta at 500 Arsenal Street, Watertown, Massachusetts 02472 (or such other address as is listed as Enanta’s primary executive offices in its periodic reports under the Securities Exchange Act of 1934) no later than September 8, 2019.23, 2021.

In addition, Enanta’s Bylaws require a stockholder who wishes to bring business before or propose director nominations at the 20202022 Annual Meeting to give advance written notice to Enanta’s Secretary not less than 45 days nor more than 60 days before the meeting;provided, however, that if less our next annual meeting is advanced more than 20 days or delayed more than 60 days’days after the anniversary of the 2022 Annual Meeting, such notice must be received in writing no earlier than the 120th day prior to such annual meeting and by the later of the close of business on the 90th day prior to such annual meeting and the 10th day following the day on which notice of the date of such annual meeting was mailed or prior public disclosure of the date of the meeting is given or made to stockholders, notice by the stockholder to be

timely must be so received no later than the close of business on the 15th day following the day on which such notice of the date of theannual meeting was mailed or such public disclosure was made.made, whichever occurs first. Assuming the 20202022 Annual Meeting is held on February 28, 2020,March 2, 2022, this would require that the advance written notice would need to be given between November 2, 2021 and December 30, 2019 and January 14, 2020.

2, 2021.  

46


AppendixAppendix A

ENANTA PHARMACEUTICALS, INC.

2019 Equity Incentive Plan

 

1.

Purpose

1.Purpose

The purpose of this 2019 Equity Incentive Plan (this “Plan”) of Enanta Pharmaceuticals, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contributions to the Company and by providing such persons with equity ownership opportunities and performance-based incentives that are intended to better align the interests of such persons with those of the Company’s stockholders.  Except where the context otherwise requires, the term “Company” shall include any of the Company’s present or future parent or subsidiary corporations as defined in Sections 424(e) or (f) of the Internal Revenue Code of 1986, as amended, and any regulations thereunder (the “Code”) and any other business venture (including, without limitation, joint venture or limited liability company) in which the Company has a controlling interest, as determined by the Board of Directors of the Company (the “Board”).

 

2.

Eligibility

2.Eligibility

All of the Company’s employees, officers and directors, as well as consultants and advisors to the Company (as such terms consultants and advisors are defined and interpreted for purposes of Form S-8 under the Securities Act of 1933, as amended (the “Securities Act”), or any successor form), are eligible to be granted Awards under this Plan.  Each person who is granted an Award under this Plan is deemed a “Participant.”  “Award” means Options (as defined in Section 5), SARs (as defined in Section 6), Restricted Stock (as defined in Section 7), Restricted Stock Units (as defined in Section 7) and Other Stock-Based Awards (as defined in Section 8).

 

3.

Administration and Delegation

3.Administration and Delegation

(a)Administration by Board of Directors.  This Plan will be administered by the Board.  The Board shall have authority to grant Awards and to adopt, amend and repeal such administrative rules, guidelines and practices relating to this Plan as it shall deem advisable.  The Board may construe and interpret the terms of this Plan and any Award certificate issued or Award agreement entered into under this Plan.  The Board may correct any defect, supply any omission or reconcile any inconsistency in this Plan or any Award in the manner and to the extent it shall deem expedient, and it shall be the sole and final judge of such expediency.  All decisions by the Board shall be made in the Board’s sole discretion and shall be final and binding on all persons having or claiming any interest in this Plan or in any Award.

(b)Appointment of Committees.  To the extent permitted by applicable law, the Board may delegate any or all of its powers under this Plan to one or more committees or subcommittees of the Board (a “Committee”).  All references in this Plan to the “Board” shall mean the Board or a Committee of the Board or the officers referred to in Section 3(c) to the extent that the Board’s powers or authority under this Plan have been delegated to such Committee or officers.

(c)Delegation to Officers.  To the extent permitted by applicable law, the Board may delegate to one or more officers of the Company the power to grant Options and other Awards that constitute rights under Delaware law (subject to any limitations under this Plan) to employees or officers of the Company and to exercise such other powers under this Plan as the Board may determine,provided that the Board shall fix the terms of such Awards to be granted by such officers (including the exercise price of such Awards, which may include a formula by which the exercise price will be determined) and the maximum number of shares subject to such Awards that the officers may grant;provided further, however, that no officer shall be authorized to grant such

Awards to any “executive officer” of the Company (as defined by Rule 3b-7 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) or to any “officer” of the Company (as defined by Rule 16a-1 under the Exchange Act).

 

4.

Stock Available for Awards

4.Stock Available for Awards

(a)Number of Shares; Share Counting.

A-1


(1)Authorized Number of Shares. Subject to adjustment under Section 9, Awards may be made under this Plan (any or all of which Awards may be in the form of Incentive Stock Options, as defined in Section 5(b)) for up to such number of shares of common stock, par value $.01 per share, of the Company (the “Common Stock”) as is equal to the sum of:

(A)1,600,000 shares of Common Stock; plus

(B)all shares of Common Stock reserved for issuance under the Company’s 2012 Equity Incentive Plan, as amended through October 1, 2018 (the “2012 Plan”) and not issued as of the date and time of stockholder approval of this Plan (including any shares reserved for issuance under the Company’s 1995 Equity Incentive Plan, as amended, that become available under the 2012 Plan), and including the 582,637 additional shares of Common Stock added on October 1, 2018 by the provision for automatic annual increases under the 2012 Plan, but not including any further increases under such provision, which provision shall have no further effect upon stockholder approval of this Plan; plus

(C)all shares of Common Stock reserved for issuance upon exercise of options or unit awards that are outstanding as of the date and time of stockholder approval of this Plan and that subsequently expire or are terminated, surrendered or canceled without having been fully exercised or are forfeited in whole or in part or result in any Common Stock not being issued and such shares becoming available for the grant of Awards under this Plan pursuant to Section 4(a)(2)(B).

For the avoidance of doubt, shares of Common Stock reserved for issuance under the 2012 Plan can only become available for issuance under this Section 4(a)(1)(C), if they are not issuable or issued under awards made under the 2012 Plan.

(D)Shares issued under this Plan may consist in whole or in part of authorized but unissued shares or treasury shares.

(2)Share Counting.  For purposes of counting the number of shares available for the grant of Awards under this Plan:

(A)all shares of Common Stock covered by SARs shall be counted against the number of shares available for the grant of Awards under this Plan;  provided, however, that (i) SARs that may be settled only in cash shall not be so counted and (ii) if the Company grants an SAR in tandem with an Option for the same number of shares of Common Stock and provides that only one such Award may be exercised (a “Tandem SAR”Tandem SAR), only the shares covered by the Option, and not the shares covered by the Tandem SAR, shall be so counted, and the expiration of one in connection with the other’s exercise will not restore shares to this Plan;

(B)if any Award under this Plan or, as applicable, the 2012 Plan (i) expires or is terminated, surrendered or canceled without having been fully exercised or is forfeited in whole or in part (including as the result of shares of Common Stock subject to such Award being repurchased by the Company at the original issuance price pursuant to a contractual repurchase right) or (ii) results in any Common Stock not being issued (including as a result of an SAR that could be settled either in cash or in stock actually being settled in cash), the unused Common Stock covered by such Award shall become available for the grant of Awards under this Plan (even if previously granted under the 2012 Plan); provided, however, that (1) in the case of Incentive Stock Options, the foregoing shall be subject to any limitations under the Code, (2) in the case of the exercise of an SAR, the number of shares counted against the shares available under this Plan shall be the full number of shares subject to the

SAR multiplied by the percentage of the SAR actually exercised, regardless of the number of shares actually used to settle such SAR upon exercise and (3) the shares covered by a tandem SAR shall not again become available for grant upon the expiration or termination of such tandem SAR;

(C)shares of Common Stock delivered (either by actual delivery, attestation, or net exercise) to the Company by a Participant under this Plan or the 2012 Plan to (i) purchase shares of Common Stock upon the exercise of an Award or (ii) satisfy tax withholding obligations (including shares retained from the Award creating the tax obligation) shall not be added back to the number of shares available for the future grant of Awards under this Plan.

A-2


(D)shares of Common Stock repurchased by the Company in the open market with the proceeds of the exercise price of an option may not be reissued under this Plan.

(b)Substitute Awards.  In connection with a merger or consolidation of an entity with the Company or the acquisition by the Company of property or stock of an entity, the Board may grant Awards in substitution for any options or other stock or stock-based awards granted by such entity or an affiliate thereof.  Substitute Awards may be granted on such terms as the Board deems appropriate in the circumstances, notwithstanding any limitations on Awards contained in this Plan.  Substitute Awards shall not count against the overall share limit set forth in Section 4(a)(1) or any sublimit contained in this Plan, except as may be required by reason of Section 422 and related provisions of the Code.

(c)Non-Employee Director Aggregate Compensation Limit.The aggregate value of all compensation granted or paid, as applicable, to any individual for service as a non-employee director of the Company with respect to any period commencing on the date of the Company’s annual meeting of stockholders for a particular year and ending on the day immediately prior to the date of the Company’s annual meeting of stockholders for the next subsequent year, including Awards granted and cash fees paid or payable by the Company to such non-employee director, will not exceed (i) $600,000 in total value or (ii) in the event such non-employee director is first appointed or elected to the Board during such period, $900,000 in total value.  The value of any Awards included in the calculation of such total value shall be based on the grant date fair value of such Awards for financial reporting purposes, and any compensation shall be counted towards these limits for the service year in which it is earned (and not when settled or paid in the event any such compensation is deferred).

 

5.

Stock Options

5.Stock Options

(a)General.  The Board may grant options to purchase Common Stock (each, an “Option”) and determine the number of shares of Common Stock to be covered by each Option, the exercise price of each Option and the conditions and limitations applicable to the exercise of each Option, including conditions relating to applicable federal or state securities laws, as it considers necessary or advisable.

(b)Incentive Stock Options.  An Option that the Board intends to be an “incentive stock option” as defined in Section 422 of the Code (an “Incentive Stock Option”) shall only be granted to employees of Enanta Pharmaceuticals, Inc., any of Enanta Pharmaceuticals, Inc.’s present or future parent or subsidiary corporations as defined in Sections 424(e) or (f) of the Code, and any other entities the employees of which are eligible to receive Incentive Stock Options under the Code, and shall be subject to and shall be construed consistently with the requirements of Section 422 of the Code.  An Option that is not intended to be an Incentive Stock Option shall be designated a “Nonstatutory Stock Option.”  The Company shall have no liability to a Participant, or any other party, if an Option (or any part thereof) that is intended to be an Incentive Stock Option is not an Incentive Stock Option or if the Company converts an Incentive Stock Option to a Nonstatutory Stock Option.  No Incentive Stock Option may be granted hereunder more than 10 years after the Effective Date (as defined in Section 11(d) and subject to reset as provided therein).

(c)Exercise Price.  The Board shall establish the exercise price of each Option and specify the exercise price in the applicable Option certificate. The exercise price shall be not less than 100% of the Fair Market Value per

share of Common Stock on the date the Option is granted;provided that if the Board approves the grant of an Option with an exercise price to be determined on a future date, the exercise price shall be not less than 100% of the Fair Market Value on such future date.“Fair Market Value”of Common Stock on any given date means thefairthe fair market value of Common Stock determined in good faith by the Board; provided, however, that if Common Stock is admitted to quotation on a national securities exchange, the determination shall be made by reference to market quotations.  If there are no market quotations for such date, the determination shall be made by reference to the last preceding such date for which there are market quotations.

(d)Duration of Options.  Each Option shall be exercisable at such times and subject to such terms and conditions as the Board may specify in the applicable option agreement;provided, however, that no Option will be granted with a term in excess of ten (10) years.

(e)Exercise of Options.  Options may be exercised by delivery to the Company of a notice of exercise in a form (which may be electronic) approved by the Company, together with payment in full (in the manner specified in Section 5(f)) of the exercise price for the number of shares for which the Option is exercised.  Shares of Common Stock subject to the Option will be delivered by the Company as soon as practicable following exercise.

A-3


(f)Payment Upon Exercise.  Common Stock purchased upon the exercise of an Option granted under this Plan shall be paid for as follows:

(1)in cash or by check, payable to the order of the Company;

(2)except as may otherwise be provided in the applicable Option certificate or approved by the Board, in its sole discretion, by (i) delivery of an irrevocable and unconditional undertaking by a creditworthy broker to deliver promptly to the Company sufficient funds to pay the exercise price and any required tax withholding or (ii) delivery by the Participant to the Company of a copy of irrevocable and unconditional instructions to a creditworthy broker to deliver promptly to the Company cash or a check sufficient to pay the exercise price and any required tax withholding;

(3)to the extent provided for in the applicable Option certificate or approved by the Board, in its sole discretion, by delivery (either by actual delivery or attestation) of shares of Common Stock owned by the Participant valued at their Fair Market Value, provided (i) such method of payment is then permitted under applicable law, (ii) such Common Stock, if acquired directly from the Company, was owned by the Participant for such minimum period of time, if any, as may be established by the Board in its discretion and (iii) such Common Stock is not subject to any repurchase, forfeiture, unfulfilled vesting or other similar requirements;

(4)to the extent provided for in the applicable Nonstatutory Stock Option certificate or approved by the Board in its sole discretion, by delivery of a notice of “net exercise” to the Company, as a result of which the Participant would receive (i) the number of shares underlying the portion of the Option being exercised, less (ii) such number of shares as is equal to (A) the aggregate exercise price for the portion of the Option being exercised divided by (B) the Fair Market Value on the date of exercise;

(5)to the extent permitted by applicable law and provided for in the applicable Option certificate or approved by the Board, in its sole discretion, by payment of such other lawful consideration as the Board may determine; or

(6)by any combination of the above permitted forms of payment.

(g)Limitation on Repricing. Unless such action is approved by the Company’s stockholders, the Company may not (except as provided for under Section 9):  (1) amend any outstanding Option granted under this Plan to provide an exercise price per share that is lower than the then-current exercise price per share of such outstanding Option, (2) cancel any outstanding option (whether or not granted under this Plan) and grant in substitution therefor new Awards under this Plan (other than Awards granted pursuant to Section 4(b)) covering the same or a

different number of shares of Common Stock and having an exercise price per share lower than the then-current exercise price per share of the cancelled option, (3) cancel in exchange for a cash payment any outstanding Option with an exercise price per share above the then-current Fair Market Value, other than pursuant to Section 9, or (4) take any other action under this Plan that constitutes a “repricing” within the meaning of the rules of the NASDAQ Stock Market.

 

6.

Stock Appreciation Rights

6.Stock Appreciation Rights

(a)General.  The Board may grant Awards consisting of stock appreciation rights (“SARs”) entitling the holder, upon exercise, to receive an amount of Common Stock or cash or a combination thereof (such form to be determined by the Board) determined by reference to appreciation, from and after the date of grant, in the Fair Market Value of a share of Common Stock over the measurement price established pursuant to Section 6(b).  The date as of which such appreciation is determined shall be the exercise date.

(b)Measurement Price.  The Board shall establish the measurement price of each SAR and specify it in the applicable SAR certificate.  The measurement price shall not be less than 100% of the Fair Market Value on the date the SAR is granted;provided that if the Board approves the grant of an SAR effective as of a future date, the measurement price shall be not less than 100% of the Fair Market Value on such future date.

(c)Duration of SARs.  Each SAR shall be exercisable at such times and subject to such terms and conditions as the Board may specify in the applicable SAR agreement;provided, however, that no SAR will be granted with a term in excess of 10 years.

(d)Exercise of SARs.  SARs may be exercised by delivery to the Company of a notice of exercise in a form (which may be electronic) approved by the Company, together with any other documents required by the Board.

A-4


(e)Limitation on Repricing. Unless such action is approved by the Company’s stockholders, the Company may not (except as provided for under Section 9):  (1) amend any outstanding SAR granted under this Plan to provide a measurement price per share that is lower than the then-current measurement price per share of such outstanding SAR, (2) cancel any outstanding SAR (whether or not granted under this Plan) and grant in substitution therefor new Awards under this Plan (other than Awards granted pursuant to Section 4(b)) covering the same or a different number of shares of Common Stock and having an exercise or measurement price per share lower than the then-current measurement price per share of the cancelled SAR, (3) cancel in exchange for a cash payment any outstanding SAR with a measurement price per share above the then-current Fair Market Value, other than pursuant to Section 9, or (4) take any other action under this Plan that constitutes a “repricing” within the meaning of the rules of the NASDAQ Stock Market.

 

7.

Restricted Stock; Restricted Stock Units

7.Restricted Stock; Restricted Stock Units

(a)General.  The Board may grant Awards entitling recipients to acquire shares of Common Stock (“Restricted Stock”), subject to the right of the Company to repurchase all or part of such shares at their issue price or other stated or formula price (or to require forfeiture of such shares if issued at no cost) from the recipient in the event that conditions specified by the Board in the applicable Award are not satisfied prior to the end of the applicable restriction period or periods established by the Board for such Award.  The Board may also grant Awards entitling the recipient to receive shares of Common Stock or cash to be delivered at the time such Award vests (“Restricted Stock Units”) (Restricted Stock and Restricted Stock Units are each referred to herein as a “Restricted Stock Award”).

(b)Terms and Conditions for All Restricted Stock Awards.  The Board shall determine the terms and conditions of a Restricted Stock Award, including the conditions for vesting and repurchase (or forfeiture) and the issue price, if any.

(c)Additional Provisions Relating to Restricted Stock.

(1)Dividends.  Any dividends (whether paid in cash, stock or property) declared and paid by the Company with respect to shares of Restricted Stock (“Accrued Dividends”) shall be paid to the Participant only if and when such shares become free from the restrictions on transferability and forfeitability that apply to such shares.  Each payment of Accrued Dividends will be made no later than the end of the calendar year in which the dividends are paid to stockholders of that class of stock or, if later, the 15th day of the third month following the lapsing of the restrictions on transferability and the forfeitability provisions applicable to the underlying shares of Restricted Stock.

(2)Other Restrictions.  The Company may require that stock transfer restrictions be implemented by the Company’s transfer agent with respect to shares of Restricted Stock, and that dividends or distributions paid on such Restricted Stock shall be deposited in escrow with the Company (or its designee) by the Participant, together with a stock power endorsed in blank.  At the expiration of the applicable restriction periods, the Company (or such designee) shall instruct the Company’s transfer agent to remove the restrictions on transfer regarding the applicable shares no longer subject to such restrictions and deliver them to the Participant, or if the Participant has died, to his or her Designated Beneficiary in accordance with appropriate instructions for electronic delivery of uncertificated shares. “Designated Beneficiary” means (i) the beneficiary designated, in a manner determined by the Board, by a Participant to receive amounts due or exercise rights of the Participant in the event of the Participant’s death or (ii) in the absence of an effective designation by a Participant, the Participant’s estate.

(d)Additional Provisions Relating to Restricted Stock Units.

(1)Settlement.  Upon the vesting of and/or lapsing of any other restrictions (i.e., settlement) with respect to each Restricted Stock Unit, the Participant shall be entitled to receive from the Company one share of Common Stock or (if so provided in the applicable Award certificate) an amount of cash equal to the Fair Market Value of one share of Common Stock.  The Board may, in its discretion, provide that settlement of Restricted Stock Units shall be deferred, on a mandatory basis or at the election of the Participant in a manner that complies with Section 409A of the Code.

(2)Voting Rights.  A Participant shall have no voting rights with respect to any Restricted Stock Units.

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(3)Dividend Equivalents.  The Award certificate for Restricted Stock Units may provide Participants with the right to receive an amount equal to any dividends or other distributions declared and paid on an equal number of outstanding shares of Common Stock (“Dividend Equivalents”).  To the extent provided in the Award certificate, Dividend Equivalents may be credited to an account for the Participant and may be settled in cash and/or shares; provided, however, that they shall be subject to the same restrictions on transfer and forfeitability as the Restricted Stock Units with respect to which they are credited.  In no case shall Dividend Equivalents on Restricted Stock Units be paid before such units vest.

 

8.

Other Stock-Based Awards

8.Other Stock-Based Awards

(a)General.  Other Awards of shares of Common Stock, and other Awards that are valued in whole or in part by reference to, or are otherwise based on, shares of Common Stock or other property (“Other Stock-Based-Awards”), may be granted hereunder to Participants.  In no case shall Dividend Equivalents with respect to Other Stock-Based Awards be paid before such Awards vest. Such Other Stock-Based Awards shall also be available as a form of payment in the settlement of other Awards granted under this Plan or as payment in lieu of compensation to which a Participant is otherwise entitled.  Other Stock-Based Awards may be paid in shares of Common Stock or cash, as the Board shall determine.

(b)Terms and Conditions.  Subject to the provisions of this Plan, the Board shall determine the terms and conditions of each Other Stock-Based Award, including any purchase price applicable thereto.

9.

Adjustments for Changes in Common Stock and Certain Other Events9.Adjustments for Changes in Common Stock and Certain Other Events

(a)Changes in Capitalization.  In the event of any stock split, reverse stock split, stock dividend, recapitalization, combination of shares, reclassification of shares, spin-off or other similar change in capitalization or event, or any dividend or distribution to holders of Common Stock other than an ordinary cash dividend, (i) the number and class of securities available under this Plan, (ii) the share counting rules set forth in Section 4(a, (iii) the number and class of securities and exercise price per share of each outstanding Option, (iv) the share and per-share provisions and the measurement price of each outstanding SAR, (v) the number of shares subject to and the repurchase price per share subject to each outstanding Restricted Stock Award and (vi) the share and per-share-related provisions and the purchase price, if any, of each outstanding Other Stock-Based Award, shall be equitably adjusted by the Company (or substituted Awards may be made, if applicable) in the manner determined by the Board.  Without limiting the generality of the foregoing, in the event the Company effects a split of the Common Stock by means of a stock dividend and the exercise price of and the number of shares subject to an outstanding Option are adjusted as of the date of the distribution of the dividend (rather than as of the record date for such dividend), then an optionee who exercises an Option between the record date and the distribution date for such stock dividend shall be entitled to receive, on the distribution date, the stock dividend with respect to the shares of Common Stock acquired upon such Option exercise, notwithstanding the fact that such shares were not outstanding as of the close of business on the record date for such stock dividend.

(b)Reorganization Events.

(1)Definition.  A “Reorganization Event” shall mean:  (a) any merger or consolidation of the Company with or into another entity as a result of which all of the Common Stock of the Company is converted into or exchanged for the right to receive cash, securities or other property or is cancelled, (b) any transfer or disposition of all of the Common Stock of the Company for cash, securities or other property pursuant to a share exchange or other transaction or (c) any liquidation or dissolution of the Company.

(2)Consequences of a Reorganization Event on Awards Other than Restricted Stock.

(A)In connection with a Reorganization Event, the Board may take any one or more of the following actions as to all or any (or any portion of) outstanding Awards other than Restricted Stock on such terms as the Board determines (except to the extent specifically provided otherwise in an applicable Award certificate or agreement or another agreement between the Company and the Participant):  (i) provide that such Awards shall be assumed, or substantially equivalent Awards shall be substituted, by the acquiring or succeeding corporation (or an affiliate thereof), (ii) upon written notice to a Participant, provide that all of the Participant’s unexercised Awards will terminate immediately prior to the consummation of such Reorganization Event unless exercised by the Participant (to the extent then exercisable) within a specified period following the date of such notice, (iii) provide that outstanding Awards shall become exercisable, realizable, or deliverable, or restrictions applicable to an Award shall lapse, in whole or in part prior to or upon such Reorganization Event, (iv) in the event of a Reorganization Event under the terms of which holders of Common Stock will receive upon consummation

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thereof a cash payment for each share surrendered in the Reorganization Event (the “Acquisition Price”), make or provide for a cash payment to Participants with respect to each Award held by a Participant equal to (A) the number of shares of Common Stock subject to the vested portion of the Award (after giving effect to any acceleration of vesting that occurs upon or immediately prior to such Reorganization Event) multiplied by (B) the excess, if any, of (I) the Acquisition Price over (II) the exercise, measurement or purchase price of such Award and any applicable tax withholdings, in exchange for the termination of such Award, (v) provide that, in connection with a liquidation or dissolution of the Company, Awards shall convert into the right to receive liquidation proceeds (if applicable, net of the exercise, measurement or purchase price thereof and any applicable tax withholdings) and (vi) any combination of the foregoing.  In taking any of the actions permitted under this Section 9(b)(2), the Board shall not be obligated by this Plan to treat all Awards, all Awards held by a Participant, or all Awards of the same type, identically.

(B)Notwithstanding the terms of Section 9(b)(2)(A), in the case of outstanding Restricted Stock Units that are subject to Section 409A of the Code: (i) if the applicable Restricted Stock Unit certificate provides that the Restricted Stock Units shall be settled upon a “change in control event” within the meaning of Treasury Regulation Section 1.409A-3(i)(5)(i), and the Reorganization Event constitutes such a “change in control event”, then no assumption or substitution shall be permitted pursuant to clause (i) of Section 9(b)(2)(A) and the Restricted Stock Units shall instead be settled in accordance with the terms of the applicable Restricted Stock Unit certificate; and (ii) the Board may only undertake the actions set forth in clauses (iii), (iv) or (v) of Section 9(b)(2)(A) if the Reorganization Event constitutes a “change in control event” as defined under Treasury RegulationSection 1.409A-3(i)(5)(i) and such action is permitted or required by Section 409A of the Code; if the Reorganization Event is not a “change in control event” as so defined or such action is not permitted or required by Section 409A of the Code, and the acquiring or succeeding corporation does not assume or substitute the Restricted Stock Units pursuant to clause (i) of Section 9(b)(2)(A), then the unvested Restricted Stock Units shall terminate immediately prior to the consummation of the Reorganization Event without any payment in exchange therefor.

(C)For purposes of clause (i) of Section 9(b)(2)(A), an Award (other than Restricted Stock) shall be considered assumed if, following consummation of the Reorganization Event, such Award confers the right to purchase or receive pursuant to the terms of such Award, for each share of Common Stock subject to the Award immediately prior to the consummation of the Reorganization Event, the consideration (whether cash, securities or other property) received as a result of the Reorganization Event by holders of Common Stock for each share of Common Stock held immediately prior to the consummation of the Reorganization Event (and if holders were offered a choice of consideration, the type of consideration chosen by the holders of a majority of the outstanding shares of Common Stock);provided, however, that if the consideration received as a result of the Reorganization Event is not solely common stock of the acquiring or succeeding corporation (or an affiliate thereof), the Company may, with the consent of the acquiring or succeeding corporation, provide for the consideration to be received upon the exercise or settlement of the Award to consist solely of such number of shares of common stock of the acquiring or succeeding corporation (or an affiliate thereof) that the Board determined to be equivalent in value (as of the date of such determination or another date specified by the Board) to the per share consideration received by holders of outstanding shares of Common Stock as a result of the Reorganization Event.

(3)Consequences of a Reorganization Event on Restricted Stock.  Upon the occurrence of a Reorganization Event other than a liquidation or dissolution of the Company, the repurchase and other rights of the Company with respect to outstanding Restricted Stock shall inure to the benefit of the Company’s successor and shall, unless the Board determines otherwise, apply to the cash, securities or other property which the Common Stock was converted into or exchanged for pursuant to such Reorganization Event in the same manner and to the same extent as they applied to such Restricted Stock;provided,however, that the Board may provide for termination or deemed satisfaction of such repurchase or other rights under the instrument evidencing any Restricted Stock or any other agreement between a Participant and the Company, either initially or by amendment.  Upon the occurrence of a Reorganization Event involving the liquidation or dissolution of the Company, except to the extent specifically provided to the contrary in the instrument evidencing any Restricted Stock or any other agreement between a Participant and the Company, all restrictions and conditions on all Restricted Stock then outstanding shall automatically be deemed terminated or satisfied.

 

10.

General Provisions Applicable to Awards

10.General Provisions Applicable to Awards

(a)Transferability of Awards.  Awards shall not be sold, assigned, transferred, pledged or otherwise encumbered by the person to whom they are granted, either voluntarily or by operation of law, except by will or the

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laws of descent and distribution or, other than in the case of an Incentive Stock Option or Awards subject to Section 409A of the Code, pursuant to a qualified domestic relations order, and, during the life of the Participant,

shall be exercisable only by the Participant;provided, however, except with respect to Awards subject to Section 409A of the Code, that the Board may permit or provide in an Award solely for the gratuitous transfer of the Award by the Participant to or for the benefit of any immediate family member, family trust or other entity established for the benefit of the Participant and/or an immediate family member thereof if the Company would be eligible to use a Form S-8 under the Securities Act for the registration of the sale of the Common Stock subject to such Award to such proposed transferee;provided further, that the Company shall not be required to recognize any such permitted transfer until such time as such permitted transferee shall, as a condition to such transfer, deliver to the Company a written instrument in form and substance satisfactory to the Company confirming that such transferee shall be bound by all of the terms and conditions of the Award.  References to a Participant, to the extent relevant in the context, shall include references to authorized transferees.  For the avoidance of doubt, nothing contained in this Section 10(a) shall be deemed to restrict a transfer to the Company.

(b)Documentation.  Each Award shall be evidenced in such form (written, electronic or otherwise) as the Board shall determine.  Each Award may contain terms and conditions inaddition to those set forth in this Plan.

(c)Board Discretion.  Except as otherwise provided by this Plan, each Award may be made alone or in addition or in relation to any other Award.  The terms of each Award need not be identical, and the Board need not treat Participants uniformly.

(d)Termination of Status.  The Board shall determine the effect of the disability, death, termination or other cessation of employment, authorized leave of absence or other change in the employment or other status of a Participant on any Award of the Participant and the extent to which, and the period during which, the Participant, or the Participant’s legal representative, conservator, guardian or Designated Beneficiary, may exercise rights under the Award.

(e)Withholding.  The Participant must satisfy all applicable federal, state, and local or other income and employment tax withholding obligations before the Company will deliver stock certificates or otherwise recognize ownership of Common Stock under an Award.  The Company may decide to satisfy the withholding obligations through additional withholding on salary or wages.  If the Company elects not to or cannot withhold from other compensation, the Participant must pay the Company the full amount, if any, required for withholding or have a broker tender to the Company cash equal to the withholding obligations.  Payment of withholding obligations is due before the Company will issue any shares on exercise, vesting or release from forfeiture of an Award or at the same time as payment of the exercise or purchase price, unless the Company determines otherwise.  If provided for in an Award or approved by the Board in its sole discretion, a Participant may satisfy such tax obligations in whole or in part by delivery (either by actual delivery or attestation) of shares of Common Stock, including shares retained from the Award creating the tax obligation, valued at their Fair Market Value.  Shares used to satisfy tax withholding requirements cannot be subject to any repurchase, forfeiture, unfulfilled vesting or other similar requirements.

(f)Amendment of Award.  Except as set forth in Section 5(g) and 6(e), the Board may amend, modify or terminate any outstanding Award, including but not limited to, substituting therefor another Award of the same or a different type, changing the date of exercise or realization, and converting an Incentive Stock Option to a Nonstatutory Stock Option.  The Participant’s consent to such action shall be required unless (i) the Board determines that the action, taking into account any related action, does not materially and adversely affect the Participant’s rights under this Plan or (ii) the change is permitted under Section 9. In addition, the Board may not take any other action that is considered a direct or indirect “repricing” for purposes of the stockholder approval rules of the applicable securities exchange or inter-dealer quotation system on which the Common Stock is listed, including any other action that is treated as a repricing under generally accepted accounting principles in the United States of America.

(g)Conditions on Delivery of Stock.  The Company will not be obligated to deliver any shares of Common Stock pursuant to this Plan or to remove restrictions from shares previously issued or delivered under this Plan

until (i) all conditions of the Award have been met or removed to the satisfaction of the Company, (ii) in the opinion of the Company’s counsel, all other legal matters in connection with the issuance and delivery of such shares have been satisfied, including any applicable securities laws and regulations and any applicable stock exchange or stock market rules and regulations, and (iii) the Participant has executed and delivered to the Company such representations or agreements as the Company may consider appropriate to satisfy the requirements of any applicable laws, rules or regulations.

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(h)Acceleration.  The Board may at any time provide that any Award shall become immediately exercisable in whole or in part, free of some or all restrictions or conditions, or otherwise realizable in whole or in part, as the case may be.

(i)Performance Awards.

(1)Awards.  Restricted Stock Awards and Other Stock-Based Awards under this Plan may be made subject to the achievement of performance measures pursuant to this Section 10(i) (“Performance Awards”).  Subject to Section 10(i)(4), no Performance Awards shall vest prior to the first anniversary of the date of grant.

(2)Performance Measures.  For any Award that is designed to be a Performance Award, the Committee may specify the degree of granting, vesting and/or payout that shall be subject to the achievement of one or moreobjective performance measures at, below, or above target measures, as the Committee may determine.  Such goals may reflect absolute entity or business unit performance or a relative comparison to the performance of a peer group of entities or other external measure of the selected performance criteria and may be absolute in their terms or measured against or in relationship to other companies comparably, similarly or otherwise situated.  Such performance measures: (i) may vary by Participant and may be different for different Awards; and (ii) may be particular to a Participant or the department, branch, line of business, subsidiary or other unit in which the Participant works and may cover such period as may be specified by the Committee.

(3)Other.  The Committee shall have the power to impose such other restrictions on Performance Awards as it may deem necessary or appropriate.

 

11.

Miscellaneous

11.Miscellaneous

(a)No Right To Employment or Other Status.  No person shall have any claim or right to be granted an Award by virtue of the adoption of this Plan, and the grant of an Award shall not be construed as giving a Participant the right to continued employment or any other relationship with the Company.  The Company expressly reserves the right at any time to dismiss or otherwise terminate its relationship with a Participant free from any liability or claim under this Plan, except as expressly provided in the applicable Award.

(b)No Rights As Stockholder.  Subject to the provisions of the applicable Award, no Participant or Designated Beneficiary shall have any rights as a stockholder with respect to any shares of Common Stock to be distributed with respect to an Award until becoming the record holder of such shares.

(c)Clawback.  Notwithstanding anything to the contrary in this Plan, the Company may recover from a Participant any compensation received from any Award (whether or not settled) or cause a Participant to forfeit any Award (whether or not vested) to the extent that the Committee or the Board determines that such forfeiture should occur in accordance with any so-called “clawback” or recoupment policy duly adopted by the Board and then in effect.

(d)Effective Date and Term of Plan.  This Plan shall become effective on the date this Plan is approved by the Company’s stockholders (the “Effective Date”).   No Awards shall be granted under this Plan after the expiration of ten (10) years from the Effective Date, but Awards previously granted may extend beyond that date.

Any increase in the maximum number of shares that may be issued under this Plan (other than an increase merely reflecting a change in the number of outstanding shares of the Company’s capital stock, such as a stock dividend or stock split) shall be considered the adoption of a new plan requiring stockholder approval under Section 422 of the Code, and any such stockholder approval shall automatically reset the Effective Date to the date of such approval and the term of this Plan shall then be extended thereby until ten (10) years from such date.

(e)Amendment of Plan.  The Board may amend, suspend or terminate this Plan or any portion thereof at any time provided that no amendment that would require stockholder approval under the rules of the NASDAQ Stock Market may be made effective unless and until the Company’s stockholders approve such amendment.  In addition, if at any time the approval of the Company’s stockholders is required as to any other modification or amendment under Section 422 of the Code or any successor provision with respect to Incentive Stock Options, the Board may not implement such modification or amendment without such approval.  Unless otherwise specified in the amendment, any amendment to this Plan adopted in accordance with this Section 11(e) shall apply to, and be binding on the holders of, all Awards outstanding under this Plan at the time the amendment is adopted, provided the Board determines that such amendment, taking into account any related action, does not materially and adversely affect the rights of Participants under this Plan.  No Award shall be made that is conditioned upon stockholder approval of any amendment to this Plan

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unless the Award provides that (i) it will terminate or be forfeited if stockholder approval of such amendment is not obtained within no more than 12 months from the date of grant and (ii) it may not be exercised or settled (or otherwise result in the issuance of Common Stock) prior to such stockholder approval.

(f)Authorization of Sub-Plans (including for Awards to non-U.S. Employees).  The Board may from time to time establish one or more sub-plans under this Plan for purposes of satisfying applicable securities, tax or other laws of various jurisdictions.  The Board shall establish such sub-plans by adopting supplements to this Plan containing (i) such limitations on the Board’s discretion under this Plan as the Board deems necessary or desirable or (ii) such additional terms and conditions not otherwise inconsistent with this Plan as the Board shall deem necessary or desirable.  All supplements adopted by the Board shall be deemed to be part of this Plan, but each supplement shall apply only to Participants within the affected jurisdiction and the Company shall not be required to provide copies of any supplement to Participants in any jurisdiction which is not the subject of such supplement.

(g)Compliance with Section 409A of the Code. Except as provided in individual Award certificates or agreements initially or by amendment, if and to the extent (i) any portion of any payment, compensation or other benefit provided to a Participant pursuant to this Plan in connection with his or her employment termination constitutes “nonqualified deferred compensation” within the meaning of Section 409A of the Code and (ii) the Participant is a specified employee as defined in Section 409A(a)(2)(B)(i) of the Code, in each case as determined by the Company in accordance with its procedures, by which determinations the Participant (through accepting the Award) agrees that he or she is bound, such portion of the payment, compensation or other benefit shall not be paid before the day that is six months plus one day after the date of “separation from service” (as determined under Section 409A of the Code) (the “New Payment Date”), except as Section 409A of the Code may then permit.  The aggregate of any payments that otherwise would have been paid to the Participant during the period between the date of separation from service and the New Payment Date shall be paid to the Participant in a lump sum on such New Payment Date, and any remaining payments will be paid on their original schedule.

The Company makes no representations or warranty and shall have no liability to the Participant or any other person if any provisions of or payments, compensation or other benefits under this Plan are determined to constitute nonqualified deferred compensation subject to Section 409A of the Code but do not to satisfy the conditions of that section.

(h)Limitations on Liability.  Notwithstanding any other provisions of this Plan, no individual acting as a director, officer, employee or agent of the Company will be liable to any Participant, former Participant, spouse, beneficiary, or any other person for any claim, loss, liability, or expense incurred in connection with this Plan,

nor will such individual be personally liable with respect to this Plan because of any contract or other instrument he or she executes in his or her capacity as a director, officer, employee or agent of the Company.  The Company will indemnify and hold harmless each director, officer, employee or agent of the Company to whom any duty or power relating to the administration or interpretation of this Plan has been or will be delegated, against any cost or expense (including attorneys’ fees) or liability (including any sum paid in settlement of a claim with the Board’s approval) arising out of any act or omission to act concerning this Plan unless arising out of such person’s own fraud or bad faith.

(i)Governing Law.  The provisions of this Plan and all Awards made hereunder shall be governed by and interpreted in accordance with the laws of the State of Delaware, excluding choice-of-law principles of the law of such state that would require the application of the laws of a jurisdiction other than the State of Delaware.

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Approved by Board on Nov. 17, 2018, and by stockholders on Feb. 28, 2019.

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ENANTA Pharmaceuticals ANNUAL MEETING OF ENANTA PHARMACEUTICALS, INC.

Date:

Thursday, February 28, 2019

Time:

4:30 P.M. (Eastern Time)

Place:

The Charles Hotel, 1 Bennett Street, Cambridge, MA 02138

Date: Tuesday March 2,2021 Time: 4:00 P.M. (Eastern Time) Place: Annual Meeting to be held Live via the internet. Please make your marks like this:visit www.proxydocs.com/ENTA  Use dark black pencil or pen only

The Board of Directors Recommends a VoteFORall director nominees listed for more details. To attend the virtual meeting and vote online during the annual meeting, you must register in proposal 1,FOR proposals 2, 4 and 5 and for1 year frequency in proposal 3.

1:

To elect two Class III directors to serve until the 2022 Annual Meeting of Stockholders or until their respective successors are elected and qualified.

Nominees:

01 Stephen Buckley, Jr.

02 Lesley Russell

Vote For

All Nominees

Withhold Vote From

All Nominees

Vote For

All Except

INSTRUCTIONS:To withhold authority to vote for any nominee, mark the “Vote For All Except” box and write the number(s) in the space provided to the right.

ForAgainstAbstain

2.

To approve the 2019 Equity Incentive Plan, which will replace the 2012 Equity Incentive Plan.
1 Year2 Years3 Years

Abstain

3.

To approve, on an advisory basis, the frequency of holding an advisory vote on the compensation paid to our named executive officers.
ForAgainstAbstain

4.

To approve, on an advisory basis, the compensation paid to our named executive officers, as disclosed in this proxy statement.
ForAgainstAbstain

5:

To ratify the appointment of PricewaterhouseCoopers LLP as Enanta’s independent registered public accounting firm for the 2019 fiscal year.

6:

To transact any other business that may properly come before the meeting or any adjournment of the meeting.

To attend the meeting and vote your sharesin person, please mark this box.
Authorized Signatures - This section must becompleted for your Instructions to be executed.

Please Sign HerePlease Date Above

Please Sign HerePlease Date Above

Please sign exactly as your name(s) appears on your stock certificate. If held in joint tenancy, all persons should sign. Trustees, administrators, etc., should include title and authority. Corporations should provide full name of corporation and title of authorized officer signing the proxy.

LOGO   Please separate carefully at the perforation and return just this portion in the envelope provided.  LOGO

LOGO

advance at www.proxydocs.com/ENTA prior to February 24,2021 at 5:00 pm Eastern Time. ENANTA Pharmaceuticals Annual Meeting of Enanta Pharmaceuticals, Inc.


to be held on Thursday, February 28, 2019

Tuesday March 2, 2021
for Holders as of January 4, 2019

Januaty 8,2021 This proxy is being solicited on behalf of the Board of Directors

VOTE BY:
              LOGO     INTERNET            LOGO     TELEPHONE

Go To

Call

www.proxypush.com/ENTA

      866-892-1702

Cast your vote online 24 hours a day/7 days a week.

OR

Use any touch-tone telephone toll-free 24 hours a day/7 days a week.

Have your Proxy Card/Voting Instructions Form ready.

LOGOMAIL


Have your Proxy Card/Voting Instruction Form ready.

Follow the simple recorded instructions.vm

View Meeting Documents.

          OR

Mark, sign and date your Proxy Card/Voting Instruction Form.

Detach your Proxy Card/Voting Instruction Form.

Return your Proxy Card/Voting Instruction Form in the

postage-paid envelope provided.

Please make your marks like this: |X| Use dark black pencil or pen only The Board of Directors Recommends a Vote FOR all director nominees listed -g in proposal 1, and FOR proposals 2,3 and 4. § 1: To elect two Class II directors to serve until the 2023 Annual Meeting of S' Stockholders or until their respective successors are elected and qualified, a Nominees: I INTERNET VOTE BY: ® TELEPHONE Go To Call www.proxypush.com/ENTA 866-892-1702 ■ Cast your vote online 24 hours a • Use any touch-tone telephone toll-free 24 hours a day/7 day/7 days a week. OR days a week. • Have your Proxy Card/Voting • Have your Proxy Card/Voting Instruction Form ready. Instructions Form ready. • Follow the simple recorded instructions.vm •View Meeting Documents. MAIL  01 Kristine Peterson 03 jz: 02 Terry Vance    Vote For Withhold Vote From Vote For O All Nominees All Nominees All Except o Q. □ □ □ c/> 1c INSTRUCTIONS: To withhold authority to  "t/> vote for any nominee, mark the “Vote For   All Except” box and write the number(s) In   the space provided to the right.   65  2. To approve an amendment to our 2019 Equity Incentive Plan. For Against Abstain □ □ □  To approve, on an advisory basis, the compensation paid to our named executive officers, as disclosed in the proxy statement. To ratify the appointment of PricewaterhouseCoopers LLP as Enanta’s independent registered public accounting firm for the 2021 fiscal year. To transact any other business that may properly come before the meeting or any adjournment of the meeting. Authorized Signatures - This section must be completed for your Instructions to be executed. □ □ □ For Against Abstain □ □ □ OR • Mark, sign and date your Proxy Card/Voting Instruction Form. Detach your Proxy Card/Voting Instruction Form. Return your Proxy Card/Voting Instruction Form in the postage-paid envelope provided. The undersigned hereby appoints Jay R. Luly, Paul J. Mellett and Nathaniel S. Gardiner, and each or any of them, as the true and lawful attorneys of the undersigned, with full power of substitution and revocation, and authorizes them, and each of them, to vote all the shares of common stock of Enanta Pharmaceuticals, Inc. which the undersigned is entitled to vote at said meeting and any adjournment thereof upon the matters specified and upon such other matters as may be properly brought before the meeting or any adjournment thereof, conferring authority upon such true and lawful attorneys to vote in their discretion on such other matters as may properly come before the meeting.

THE SHARES REPRESENTED BY THIS PROXY WILL BE VOTED AS DIRECTED OR, IF NO DIRECTION IS GIVEN, SHARES WILL BE VOTED FOR THE ELECTION OF THE DIRECTORS IN ITEM 1 AND FOR THE PROPOSALS IN ITEMS 2, 43 AND 5 AND FOR 1-YEAR FREQUENCY IN ITEM 3.4. THE PROXIES WILL VOTE IN THEIR DISCRETION ON ANY OTHER BUSINESS AS MAY PROPERLY COME BEFORE THE MEETING AND ANY ADJOURNMENT THEREOF. PROXY TABULATOR FOR  ENANTA PHARMACEUTICALS, INC. c/o MEDIANT COMMUNICATIONS P.O. BOX 8016 CARY, NC 27512-9903 Please Sign Here Please Sign Here Please Date Above Please Date Abovea Please sign exactly as your name(s) appears on your stock certificate. If held in joint tenancy, all persons should sign. Trustees, administrators, etc., should include title and authority. Corporations should provide full name of corporation and title of authorized officer signing the proxy.  

 

 

PROXY TABULATOR FOR

ENANTA PHARMACEUTICALS, INC.

c/o MEDIANT COMMUNICATIONS

P.O. BOX 8016

CARY, NC 27512-9903


 

EVENT #

CLIENT #

E NANTA Pharmaceuticals Proxy for Annual Meeting of Stockholders to be held
on Tuesday March 2,2021 This proxy is being solicited on behalf of the Board of Directors Please vote, date and sign this Proxy on the other side and return
it in the enclosed envelope. The Stockholder signing on the reverse side (the “undersigned”), having received the Annual Report and Proxy Statement, hereby appoint(s) Jay R. Luly, Paul J. Mellett and Nathaniel S. Gardiner, and each of them, Proxies of the undersigned (with full power of substitution) to attend the Annual Meeting of Enanta Pharmaceuticals, Inc. (the “Company”) to be held on Tuesday March 2, 2021, and all adjournments and postponements thereof (the “Meeting”), and to vote all shares of Common Stock of the Company that the undersigned would be entitled to vote, if personally present, in regard to all matters that may properly come before the Meeting. The undersigned hereby confer(s) upon the Proxies, and each of them, discretionary authority to consider and act upon such business, matters or proposals as may properly come before the Meeting. The Proxy, when properly executed, will be voted in the manner specified herein. If no specification is made, the Proxies intend to vote FOR all nominees for director in Proposal 1 and FOR proposals 2,3 and 4. 1
s Please separate carefully at the perforation and return just this portion in the envelope provided, "t